The juvenile hormone analogue (JHA) 6′, 7′,-epxy-3, 7′-dimethyl-undec-2′-enyl 6-ethyl-3-pyridyl ether at 10 ppm (v/v) applied to whole wheat grains was not toxic to adult insects, but effectively reduced the F1 generation of the lesser grain borer, Rhizopertha dominica (F.). However, topical applications of 4 ppm (v/v) of the JHA prevented normal metamorphosis of the larvae and pupae; all the test insects died due to morphogenetic abnormalities induced by treatment with the JHA.