The present paper introduces a tumormodel with two time scales, the time t during which the tumorgrows and the cycle time of individual cells. The model alsoincludes the effects of gene mutations on the population densityof the tumor cells. The model is formulated as a free boundaryproblem for a coupled system of elliptic, parabolic and hyperbolicequations within the tumor region, with nonlinear and nonlocalterms. Existence and uniqueness theorems are proved, andproperties of the free boundary are established.