We study the stability of the differential process of Rochberg and Weiss associated with an analytic family of Banach spaces obtained using the complex interpolation method for families. In the context of Köthe function spaces, we complete earlier results of Kalton (who showed that there is global bounded stability for pairs of Köthe spaces) by showing that there is global (bounded) stability for families of up to three Köthe spaces distributed in arcs on the unit circle while there is no (bounded) stability for families of four or more Köthe spaces. In the context of arbitrary pairs of Banach spaces, we present some local stability results and some global isometric stability results.