Aqueous extracts (5%) of the seeds Parkia clappertoniana (Jacq), Azadirachta indica A. Juss, and Piper guineense Schum and Thonn caused 90% mortalityof the worker caste with P. guineense, and 86% mortality with A. indica and P. clappertoniana respectively within 3 hr of topical application. At 24 hr, mortality of Macrotermes nigeriensis (Sjostedti) workers was 100% with the same concentration of each extract. Oral toxicity at 3 hr to the worker caste using cuttings of cassava, Manihotesculenta Crantz impregnated with each extract gave 65% mortality with Piper, and 45 and 29% with Azadirachta and Parkia, respectively. Mortalityby oral toxicity reached 100% in 12 hr with Piper, 95 and 69%, respectively with Azadirachta and Parkia. Increasing the concentrations of each extract to 15% did not significantly (P > 0.05) increase the toxicities of the extracts to the worker caste even at prolonged exposure periods.