Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-28T13:22:43.587Z Has data issue: false hasContentIssue false

Debate 26A - What is the Best Management Strategy for a Recurrent Granulosa Cell Tumor?

Surgery

from Section III - Ovarian Cancer

Published online by Cambridge University Press:  20 July 2023

By
Alice Bergamini ,
Luca Bocciolone  and
Gioriga Mangili
Edited by
Dennis S. Chi ,
Nisha Lakhi  and
Nicoletta Colombo
Dennis S. Chi
Affiliation:
Memorial Sloan-Kettering Cancer Center, New York
Nisha Lakhi
Affiliation:
Richmond University Medical Center, Staten Island
Nicoletta Colombo
Affiliation:
University of Milan-Bicocca
Get access

Summary

Among patients diagnosed with stage I granulosa cell tumors (GCTs) of the ovary, 25% will experience recurrent disease, after a median of four to six years from initial diagnosis [1]. GCTs are rare tumors and have a slow, indolent course, with recurrences registered even after several decades from initial diagnosis [2].

Type
Chapter
Information
50 Big Debates in Gynecologic Oncology , pp. 152 - 154
Publisher: Cambridge University Press
Print publication year: 2023

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Thrall, MM et al. Patterns of spread and recurrence of sex cord-stromal tumors of the ovary. Gynecol Oncol 2001;122:242–245.CrossRefGoogle Scholar
Hines, JF, et al. Recurrent granulosa cell tumor of the ovary 37 years after initial diagnosis: a case report and review of the literature. Gynecol Oncol 1996;60(3):484–488.CrossRefGoogle ScholarPubMed
Sun, HD, et al. A long-term follow-up study of 176 cases with adult type ovarian granulosa cell tumors. Gynecol Oncol 2012;124(2):244–249.CrossRefGoogle ScholarPubMed
Mangili, G, et al.Recurrent granulosa cell tumors (GCTs) of the ovary: a MITO-9 retrospective study. Gynecol Oncol 2013;130(1):38–42.CrossRefGoogle ScholarPubMed
Hölscher, G, et al. Improvement of survival in sex cord stromal tumors – an observational study with more than 25 years follow-up. Acta Obstet Gynecol Scand 2009;88:440e8.CrossRefGoogle ScholarPubMed
Fotopolou, C, et al. Adult granulosa cell tumors of the ovary: tumor dissemination pattern at primary and recurrent situation, surgical outcome. Gynecol Oncol 2010;119:285–290.CrossRefGoogle Scholar
Lee, YK, et al. Characteristics of recurrence in adult-type granulosa cell tumos. Int J Gynecol Cancer 2008;18:642–647.CrossRefGoogle Scholar
Abu-Rustum, NR, et al. Retroperitoneal nodal metastasis in primary and recurrent granulosa cell tumors of the ovary. Gynecol Oncol 2006;103:31.CrossRefGoogle ScholarPubMed
Wang, PH, et al. Outcome of patients with recurrent adult-type granulosa cell tumors – a Taiwanese Gynecologic Oncology Group study. Taiwan J Obstet Gynecol 2015;54(3):253–259.CrossRefGoogle ScholarPubMed
Zhao, D, et al. Characteristics and treatment results of recurrence in adult-type granulosa cell tumor of ovary. J Ovarian Res 2020;13(1):19.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×