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49B - Progesterone Levels Should Be Measured on the Day of hCG Administration

Against

from Section IX - Hormones and the Environment

Published online by Cambridge University Press:  25 November 2021

By
Alan Penzias
Edited by
Roy Homburg ,
Adam H. Balen  and
Robert F. Casper
Roy Homburg
Affiliation:
Homerton University Hospital, London
Adam H. Balen
Affiliation:
Leeds Centre for Reproductive Medicine
Robert F. Casper
Affiliation:
Mount Sinai Hospital, Toronto
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Summary

Measurement of serum progesterone level may be useful in a natural, unmedicated menstrual cycle to determine whether the hormonal events associated with ovulation have occurred. In pharmacologically managed fertility treatment cycles the role of a progesterone level is diminished significantly. Checking the progesterone level on the day of hCG administration rarely adds value to treatment, may be misleading and risks causing an unnecessary change in patient management.

Type
Chapter
Information
50 Big Debates in Reproductive Medicine , pp. 257 - 258
Publisher: Cambridge University Press
Print publication year: 2021

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References

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Racca, A, Santos-Ribeiro, S, De Munch, N, et al. Impact of late-follicular phase elevated serum progesterone on cumulative live birth rates: is there a deleterious effect on embryo quality? Hum Reprod. 2018;33:860–68.CrossRefGoogle Scholar
Humm, KC, Ibrahim, Y, Dodge, LE, et al. Does elevated serum progesterone on the day of human chorionic gonadotropin administration decrease live birth rates? J Reprod Med. 2012;57:9–12.Google Scholar
Ubaldi, F, Smitz, J, Wisanto, A, et al. Oocyte and embryo quality as well as pregnancy rate in intracytoplasmic sperm injection are not affected by high follicular phase serum progesterone. Hum Reprod. 1995;10:3091–6.CrossRefGoogle Scholar

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