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5 - CT in Esophageal Cancer

Published online by Cambridge University Press:  08 August 2009

By
Naama R. Bogot  and
Leslie Eisenbud Quint
Edited by
Sheila C. Rankin
Naama R. Bogot
Affiliation:
Department of Radiology, Hadassah Hebrew University, Medical Centre, Jerusalem, Israel; Lecturer, Department of Radiology, Division of Cardiothoracic Imaging, Division of Cardiothoracic Imaging, USA
Leslie Eisenbud Quint
Affiliation:
Professor of Radiology, Division of Cardiothoracic Imaging, University of Michigan Health System, USA
Sheila C. Rankin
Affiliation:
Guy's and St Thomas' Hospital
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Summary

Introduction

Cross-sectional imaging with computer tomography (CT) and magnetic resonance imaging (MRI) has no significant role in diagnosing esophageal cancer, although it is complementary to endoscopy, barium studies, endoscopic ultrasound (EUS), and positron emission tomography (PET) imaging in the staging of esophageal cancer. Accurate staging is necessary in order to prompt appropriate curative or palliative therapy. While CT and MRI are insensitive for delineating tumor invasion into and through the esophageal wall, these modalities play a role in estimating the esophageal tumor bulk, evaluating for local spread into adjacent structures, and diagnosing distant metastases, when present. Cross-sectional imaging also has an important role in the follow-up of esophageal cancer patients after treatment, to assess response to chemoradiotherapy and to evaluate recurrence after treatment.

Anatomy and staging

Knowledge of esophageal anatomy is important both for understanding how esophageal cancer spreads and for staging purposes. The esophageal wall consists of four layers: mucosa, submucosa, muscularis propria, and adventitia (Figure 5.1). There is no serosa to serve as a barrier between the esophagus and the surrounding structures; lack of a serosa facilitates tumor spread through the esophageal wall into adjacent structures. A rich plexus of lymphatics encircles the entire length of the esophagus, enabling lymphatic spread of tumor to mediastinal, cervical, and upper abdominal lymph nodes (Figure 5.2). An experimental study showed that dye injected into the esophageal wall at one level may drain to lymph nodes at all other levels of the esophagus in some patients and also frequently drains directly into the thoracic duct, potentially leading to hematogenous metastases.

Type
Chapter
Information
Carcinoma of the Esophagus , pp. 62 - 84
Publisher: Cambridge University Press
Print publication year: 2007

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  • CT in Esophageal Cancer
    • By Naama R. Bogot, Department of Radiology, Hadassah Hebrew University, Medical Centre, Jerusalem, Israel; Lecturer, Department of Radiology, Division of Cardiothoracic Imaging, Division of Cardiothoracic Imaging, USA, Leslie Eisenbud Quint, Professor of Radiology, Division of Cardiothoracic Imaging, University of Michigan Health System, USA
  • Edited by Sheila C. Rankin
  • Book: Carcinoma of the Esophagus
  • Online publication: 08 August 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511545443.007
Available formats
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  • CT in Esophageal Cancer
    • By Naama R. Bogot, Department of Radiology, Hadassah Hebrew University, Medical Centre, Jerusalem, Israel; Lecturer, Department of Radiology, Division of Cardiothoracic Imaging, Division of Cardiothoracic Imaging, USA, Leslie Eisenbud Quint, Professor of Radiology, Division of Cardiothoracic Imaging, University of Michigan Health System, USA
  • Edited by Sheila C. Rankin
  • Book: Carcinoma of the Esophagus
  • Online publication: 08 August 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511545443.007
Available formats
×

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To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • CT in Esophageal Cancer
    • By Naama R. Bogot, Department of Radiology, Hadassah Hebrew University, Medical Centre, Jerusalem, Israel; Lecturer, Department of Radiology, Division of Cardiothoracic Imaging, Division of Cardiothoracic Imaging, USA, Leslie Eisenbud Quint, Professor of Radiology, Division of Cardiothoracic Imaging, University of Michigan Health System, USA
  • Edited by Sheila C. Rankin
  • Book: Carcinoma of the Esophagus
  • Online publication: 08 August 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511545443.007
Available formats
×