Book contents
- Environmental Impacts on Reproductive Health and Fertility
- Environmental Impacts on Reproductive Health and Fertility
- Copyright page
- Contents
- Contributors
- Preface
- Acknowledgments
- 1. Introduction
- 2. Environmental contaminants and exposure
- 3. Development and maturation of the normal female reproductive system
- 4 Development and maturation of the normal male reproductive system
- 5 Modern genetics of reproductive biology
- 6. Mechanisms of endocrine disruption
- 7. Developmental exposures and implications for early and latent disease
- 8 Wildlife as sentinels of environmental impacts on reproductive health and fertility
- 9 Environmental contaminants and effects on timing and progression of human pubertal development
- 10 Environmental contaminants and impacts on healthy and successful pregnancies
- 11 Environmental contaminants and reproductive and fertility effects in the male
- 12. Environmental contaminants, female reproductive health and fertility
- 13 Environmental contaminants and related systems that have implications for reproduction
- 14 Environmental contaminants and cancers of the reproductive tract
- 15 Communicating with patients and the public about environmental exposures and reproductive risk
- 16 Interpreting science in the policy context
- 17 Conclusions – what does all this mean, and where are we going?
- Index
17 - Conclusions – what does all this mean, and where are we going?
Published online by Cambridge University Press: 23 February 2010
Book contents
- Environmental Impacts on Reproductive Health and Fertility
- Environmental Impacts on Reproductive Health and Fertility
- Copyright page
- Contents
- Contributors
- Preface
- Acknowledgments
- 1. Introduction
- 2. Environmental contaminants and exposure
- 3. Development and maturation of the normal female reproductive system
- 4 Development and maturation of the normal male reproductive system
- 5 Modern genetics of reproductive biology
- 6. Mechanisms of endocrine disruption
- 7. Developmental exposures and implications for early and latent disease
- 8 Wildlife as sentinels of environmental impacts on reproductive health and fertility
- 9 Environmental contaminants and effects on timing and progression of human pubertal development
- 10 Environmental contaminants and impacts on healthy and successful pregnancies
- 11 Environmental contaminants and reproductive and fertility effects in the male
- 12. Environmental contaminants, female reproductive health and fertility
- 13 Environmental contaminants and related systems that have implications for reproduction
- 14 Environmental contaminants and cancers of the reproductive tract
- 15 Communicating with patients and the public about environmental exposures and reproductive risk
- 16 Interpreting science in the policy context
- 17 Conclusions – what does all this mean, and where are we going?
- Index
Summary
Leaders in environmental health and science have summarized the most current information about environmental contaminants and exposures, and their relevance to reproductive health and reproductive disorders. Many chemicals that affect reproductive health are endocrine disruptors, which are mimetics or antagonists of naturally occurring steroid hormones, or chemicals that have the capacity to alter the metabolism, half-life, secretion, and excretion of endogenous hormones. Advances in health technologies to monitor biological actions of chemicals, along with advances in systems biology, including bioinformatics, computational technologies to quantify and characterize effects of thousands of chemicals on cellular functions, biochemical pathways and cellular components offer an opportunity to revolutionize toxicology testing. Regarding assessment of risk, the National Academy of Sciences (NAS) has recently published a summary of special analysis of science and decisions: advancing risk assessment that is particularly relevant to environmental risk assessment.
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- Information
- Publisher: Cambridge University PressPrint publication year: 2010