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Chapter 20 - Children and Adolescents

Published online by Cambridge University Press:  07 November 2024

By
Mark Lovell ,
Ashley Liew  and
Keir Jones
Edited by
David M. L. Branford ,
Satheesh K. Gangadharan ,
Mary Barrett  and
Regi T. Alexander
David M. L. Branford
Affiliation:
Independent Pharmacy Consultant
Satheesh K. Gangadharan
Affiliation:
Leicestershire Partnership NHS Trust
Mary Barrett
Affiliation:
Leicestershire Partnership NHS Trust
Regi T. Alexander
Affiliation:
Hertfordshire Partnership University NHS Foundation Trust
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Summary

There is an increasing trend of the prescribing of psychotropic medications for children. This chapter explores the various issues associated with medicating children with people with intellectual disability.

Keywords

ADHDautismbehaviourSTOMP-STAMPrisperidonearipiprazole
Type
Chapter
Information
The Frith Prescribing Guidelines for People with Intellectual Disability , pp. 297 - 308
Publisher: Cambridge University Press
Print publication year: 2024

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References

Key References and Guidelines

NICE Guideline (2015) – Challenging Behaviour and Learning Disabilities: Prevention and interventions for people with learning disabilities whose behaviour challenges. www.nice.org.uk/guidance/ng11.Google Scholar
NICE Guideline (2016) – Mental health problems in people with learning disabilities: prevention, assessment and management. www.nice.org.uk/guidance/ng54.Google Scholar
Totsika, V., Liew, A., Absoud, M., Adnams, C. & Emerson, E. (2022) Mental health problems in children with intellectual disability. The Lancet Child & Adolescent Health 6, 432–44. https://doi.org/10.1016/S2352-4642(22)00067-0.CrossRefGoogle ScholarPubMed
Siegel, M., McGuire, K., Veenstra-VanderWeele, J., et al. (2020) Practice parameter for the assessment and treatment of psychiatric disorders in children and adolescents with intellectual disability (intellectual developmental disorder). Journal of the American Academy of Child & Adolescent Psychiatry 59, 468–96. https://doi.org/10.1016/j.jaac.2019.11.018.Google ScholarPubMed
Allington-Smith, P. (2006) Mental health of children with learning disabilities. Advances in Psychiatric Treatment 12, 130–8. https://doi.org/10.1192/apt.12.2.130.CrossRefGoogle Scholar

References

Aman, M. G., De Smedt, G., Derivan, A., et al. 2002. Double-blind, placebo-controlled study of risperidone for the treatment of disruptive behaviors in children with subaverage intelligence. AJP 159, 1337–46. https://doi.org/10.1176/appi.ajp.159.8.1337.Google ScholarPubMed
Aman, M. G., Kern, R. A., McGhee, D. E., & Arnold, L. E., 1993. Fenfluramine and methylphenidate in children with mental retardation and ADHD: Clinical and side effects. Journal of the American Academy of Child & Adolescent Psychiatry 32, 851–9. https://doi.org/10.1097/00004583-199307000-00022.Google ScholarPubMed
Buckley, N., Glasson, E. J., Chen, W., et al. 2020. Prevalence estimates of mental health problems in children and adolescents with intellectual disability: A systematic review and meta-analysis. Aust N Z J Psychiatry 54, 970–84. https://doi.org/10.1177/0004867420924101.CrossRefGoogle ScholarPubMed
Einfeld, S. L., Ellis, L. A., & Emerson, E., 2011. Comorbidity of intellectual disability and mental disorder in children and adolescents: A systematic review. Journal of Intellectual & Developmental Disability 36, 137–43. https://doi.org/10.1080/13668250.2011.572548.CrossRefGoogle ScholarPubMed
Emerson, E., & Hatton, C., 2007. Mental health of children and adolescents with intellectual disabilities in Britain. British Journal of Psychiatry 191, 493–9. https://doi.org/10.1192/bjp.bp.107.038729.CrossRefGoogle ScholarPubMed
Fernández-Jaén, A., Fernández-Mayoralas, D.M., Calleja Pérez, B., Muñoz Jareño, N., & del Rosario Campos Díaz, M., 2010. Atomoxetine for attention deficit hyperactivity disorder in mental retardation. Pediatric Neurology 43, 341–7. https://doi.org/10.1016/j.pediatrneurol.2010.06.003.CrossRefGoogle ScholarPubMed
Findling, R. L., Aman, M. G., Eerdekens, M., et al. 2004. Long-term, open-label study of risperidone in children with severe disruptive behaviors and below-average IQ. AJP 161, 677–84. https://doi.org/10.1176/appi.ajp.161.4.677.Google ScholarPubMed
Handen, B. L., Feldman, H. M., Lurier, A., & Murray, P. J. H., 1999. Efficacy of methylphenidate among preschool children with developmental disabilities and ADHD. Journal of the American Academy of Child and Adolescent Psychiatry 38, 805–12.Google ScholarPubMed
Ichikawa, H., Mikami, K., Okada, T., et al. 2017. Aripiprazole in the treatment of irritability in children and adolescents with autism spectrum disorder in Japan: A randomized, double-blind, placebo-controlled study. Child Psychiatry Hum Dev 48, 796–806. https://doi.org/10.1007/s10578-016-0704-x.CrossRefGoogle ScholarPubMed
Simonoff, E., Taylor, E., Baird, G., et al. 2013. Randomized controlled double-blind trial of optimal dose methylphenidate in children and adolescents with severe attention deficit hyperactivity disorder and intellectual disability: Methylphenidate for hyperkinetic disorder in children with intellectual disability. Journal of Child Psychology and Psychiatry 54, 527–35. https://doi.org/10.1111/j.1469-7610.2012.02569.x.CrossRefGoogle Scholar

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