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8 - Genomics of Cardiometabolic Disorders in Sub-Saharan Africa

Published online by Cambridge University Press:  02 December 2019

By
Sally N. Adebamowo ,
Fasil Tekola-Ayele ,
Adebowale A. Adeyemo  and
Charles N. Rotimi
Edited by
Muntaser E. Ibrahim  and
Charles N. Rotimi
Muntaser E. Ibrahim
Affiliation:
University of Khartoum
Charles N. Rotimi
Affiliation:
National Human Genome Research Institute/NIH
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Summary

Cardiometabolic disorders including hypertension, diabetes, dyslipidemia, obesity, coronary heart disease (CHD), and stroke have been established as major contributors to the global burden of disease, disability, and mortality. Although cardiometabolic disorders were considered to be primarily prevalent in high-income countries (HICs), current indications identify their increasing public health impact in all regions of the world, particularly in lower middle income countries (LMICs). Between 2013 and 2100, the populations of 35 countries, most of them LMICs, could more than triple (United Nations 2013). Among them, the populations of Burundi, Malawi, Mali, Niger, Nigeria, Somalia, Uganda, United Republic of Tanzania, and Zambia are projected to increase at least five-fold by 2100 (United Nations 2013). The fast rate of population growth, increase in life expectancy, urbanization, and the shift from communicable to non-communicable diseases in these countries suggests an alarming trend of increase in cardiometabolic diseases in Africa in the near future.

Type
Chapter
Information
The Genetics of African Populations in Health and Disease , pp. 168 - 198
Publisher: Cambridge University Press
Print publication year: 2019

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