from Section 3 - Specific Neurological Disorders in Emergency Medicine
Published online by Cambridge University Press: 10 January 2024
The cranial vault in an adult is an enclosed space encased by the rigid skull. The Monro–Kellie doctrine proposed in the early nineteenth century states that the volume inside the cranium is fixed and normally filled with the brain, cerebral spinal fluid, and blood in a state of equilibrium. An increase in the volume of one of these constituents must be compensated by a decrease in another. Intracranial pressure (ICP) is the pressure inside the skull due to the volume within the cranium. Elevated ICP can be severely debilitating and even life-threatening. It is very important to quickly identify signs and symptoms of elevated ICP, diagnose the pathology, and promptly initiate treatment in the emergency setting to prevent irreparable brain damage, significant disability, or death.
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