from Section 3.7 - Infection and Immunity
Published online by Cambridge University Press: 27 July 2023
Key Learning Points
1. Malaria is caused by a protozoan parasite of the Plasmodium genus, transmitted by mosquitoes.
2. There are five species of Plasmodium that regularly infect humans; Plasmodium falciparum is responsible for the vast majority of malarial deaths.
3. Severe malaria is a medical emergency, with mortality from untreated disease (particularly cerebral malaria) approaching 100 per cent. Early diagnosis and prompt, effective treatment are essential.
4. Parenteral artesunate is the treatment of choice for all severe malaria.
5. It is important to remember there are many causes of critical illness in the returning traveller, with a wide number of differentials, including, but not limited to: enteric fever (typhoid and paratyphoid), hepatitis, dengue or other arboviruses, avian influenza and viral haemorrhagic fever.
To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Find out more about the Kindle Personal Document Service.
To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.
To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.