Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-26T18:07:42.191Z Has data issue: false hasContentIssue false

3.11.6 - Phosphate

from Section 3.11 - Metabolic Disorders

Published online by Cambridge University Press:  27 July 2023

By
Clare Morkane
Edited by
Ned Gilbert-Kawai ,
Debashish Dutta  and
Carl Waldmann
Ned Gilbert-Kawai
Affiliation:
The Royal Liverpool Hospital
Debashish Dutta
Affiliation:
Princess Alexandra Hospital NHS Trust, Harlow
Carl Waldmann
Affiliation:
Royal Berkshire Hospital, Reading
Get access

Summary

Key Learning Points

  1. 1. Phosphate and calcium are intimately related; both are under tight physiological control.

  2. 2. Phosphate plays a critical role in a number of processes, including energy metabolism, cellular signalling, bone mineralisation and membrane integrity.

  3. 3. Hypophosphataemia is a commonly encountered electrolyte abnormality in critically ill patients.

  4. 4. Disturbances in phosphate level are often multifactorial in aetiology.

  5. 5. Hypophosphataemia can result in respiratory failure and difficulty weaning from mechanical ventilation.

Keywords

phosphatehypophosphataemiahyperphosphataemia
Type
Chapter
Information
Intensive Care Medicine
The Essential Guide
 , pp. 375
Publisher: Cambridge University Press
Print publication year: 2021

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

References and Further Reading

Gaasbeek, A, Meinders, AE. Hypophosphatemia: an update on its etiology and treatment. Am J Med 2005;118:1094–101.CrossRefGoogle ScholarPubMed
Penido, MG, Alon, US. Phosphate homeostasis and its role in bone health. Pediatr Nephrol 2012;27:2039–48.CrossRefGoogle Scholar
Wadsworth, RL, Siddiqui, S. Phosphate homeostasis in critical care. BJA Educ 2016;16:305–9.CrossRefGoogle Scholar
Weisinger, JR, Bellorín-Font, E. Magnesium and phosphorus. Lancet 1998;352:391–6.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×