Skip to main content Accessibility help
×
Hostname: page-component-cd9895bd7-8ctnn Total loading time: 0 Render date: 2024-12-26T15:33:35.608Z Has data issue: false hasContentIssue false

Case 32 - Myasthenia Gravis with Muscle-Specific Kinase Antibodies (MuSK MG)

from Disorders of the Neuromuscular Junction

Published online by Cambridge University Press:  29 November 2024

Jessica E. Hoogendijk
Affiliation:
University Medical Center Utrecht
Marianne de Visser
Affiliation:
Amsterdam University Medical Center
Pieter A. van Doorn
Affiliation:
Erasmus MC, University Medical Center, Rotterdam
Erik H. Niks
Affiliation:
Leiden University Medical Center
Get access

Summary

Over a period of months, a 45-year-old woman noticed that she had difficulty raising her arms. She also reported double vision in the evening that, in retrospect, had been present for some years. Three years later, it became difficult to keep her head up without support, to chew, and to swallow, which sometimes worsened over a period of weeks.

Type
Chapter
Information
Neuromuscular Disease
A Case-Based Approach
, pp. 161 - 162
Publisher: Cambridge University Press
Print publication year: 2024

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Suggested Reading

Brauner, S, Eriksson-Dufva, A, Hietala, MA, et al. Comparison between rituximab treatment for new-onset generalized myasthenia gravis and refractory generalized myasthenia gravis. JAMA Neurol 2020;77:974981. doi: 10.1001/jamaneurol.2020.0851.CrossRefGoogle ScholarPubMed
Gilhus, NE. Myasthenia gravis can have consequences for pregnancy and the developing child. Front Neurol 2020 Jun 12;11:554. doi: 10.3389/fneur.2020.00554. PMID: 32595594; PMCID: PMC7304249.CrossRefGoogle ScholarPubMed
Cao, M, Koneczny, I, Vincent, A. Myasthenia gravis with antibodies against muscle specific kinase: an update on clinical features, pathophysiology and treatment. Front Mol Neurosci 2020;13:159. doi: 10.3389/fnmol.2020.00159CrossRefGoogle Scholar
Narayanaswami, P, Sanders, DB, Wolfe, G, et al. International consensus guidance for management of myasthenia gravis: 2020 update. Neurology 2021;96:114122. doi:10.1212/WNL.0000000000011124CrossRefGoogle ScholarPubMed
Verschuuren, JJ, Palace, J, Murai, H, et al. Advances and ongoing research in the treatment of autoimmune neuromuscular junction disorders. Lancet Neurol 2022;21(2):189202. doi: 10.1016/S1474-4422(21)00463-4. Erratum in: Lancet Neurol. 2022 Mar;21(3):e3. PMID: 35065041.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×