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Chapter 26 - Late Effects of Chemoradiotherapy on Fertility and Pregnancy

from Section 9 - Malignant Conditions

Published online by Cambridge University Press:  01 February 2018

Sue Pavord
Affiliation:
University of Oxford
Beverley Hunt
Affiliation:
King's College London
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Publisher: Cambridge University Press
Print publication year: 2018

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References

Meirow, D, Dor, J, Kaufman, A et al. Cortical fibrosis and blood-vessels damage in human ovaries exposed to chemotherapy. Potential mechanisms of ovarian injury. Human Reproduction 2007; 22: 16261633.Google Scholar
Tilly, JL. Pharmacological protection of female infertility. In Tulandi, T, Gosden, R (eds) Preservation of Fertility. London:Taylor and Francis; 2004: 6575.Google Scholar
Kalich-Philosoph, L, Roness, H, Carmely, A et al. Cyclophosphamide triggers follicle activation and ‘burnout’; AS101 prevents follicle loss and preserves fertility. Science Translational Medicine 2013; 5: 185ra62CrossRefGoogle ScholarPubMed
Peigne, M, Decanter, C. Serum AMH level as a marker of acute and long-term effects of chemotherapy on the ovarian follicular content: a systematic review. Reproductive Biology and Endocrinology 2014; 12: 26.Google Scholar
Critchley, HO, Wallace, WH, Shalet, SM et al. Abdominal irradiation in childhood: the potential for pregnancy. British Journal of Obstetrics and Gynecology 1992; 97: 804810.Google Scholar
Wallace, WHB, Thomson, AB, Kelsey, TW. The radiosensitivity of the human oocyte. Human Reproduction 2003; 18: 117121.Google Scholar
Littley, MD, Shalet, SM, Beardwell, CG et al. Hypopituitarism following external radiotherapy for pituitary tumours in adults. Quaterley Journal of Medicine 1989; 70: 145160.Google Scholar
Green, DM, Nolan, VG, Kawashima, MS et al. Decreased fertility among female childhood cancer survivors who received 22-27 G hypothalamic/pituitary irradiation: a report from the childhood cancer survivor study. Fertility and Sterility 2011; 95: 19221927.Google Scholar
Sudour, H, Chastagner, P, Claude, L, et al. Fertility and pregnancy outcome after abdominal irradiation that included or excluded the pelvis in childhood tumor survivors. International Journal of Radiation Oncology Biology Physics 2010; 76: 867873.CrossRefGoogle ScholarPubMed
The, T, Stern, C, Chander, S, Hickey, M. The impact of uterine radiation on subsequent fertility and pregnancy outcomes. BioMed Research International 2014; Article ID 482968.Google Scholar
Sanders, JE, Buckner, CD, Amos, D et al. Ovarian function following marrow transplantation for aplastic anemia or leukemia. Journal of Clinical Oncology 1988; 6: 813818.CrossRefGoogle ScholarPubMed
Holm, K, Nysom, K, Brocks, V et al. Ultrasound B-mode changes in the uterus and ovaries and Doppler changes in the uterus after total body irradiation and allogeneic bone marrow transplantation. Bone Marrow Transplantation 1999; 23: 259263.Google Scholar
Meirow, D. Reproduction post-chemotherapy in young cancer patients. Molecular Cell Endocrinology 2000; 169: 123131.Google Scholar
Koyama, H, Wada, T, Nishizawa, Y et al. Cyclophosphamide-induced ovarian failure and its therapeutic significance in patients with breast cancer. Cancer 1977; 39: 14031409.Google Scholar
Sanders, JE, Hawley, J, Levy, W et al. Pregnancies following high-dose cyclophosphamide with or without high-dose busulfan or total-body irradiation and bone marrow transplantation. Blood 1996; 87: 30453052.Google Scholar
Salooja, N, Szydlo, RM, Socie, G et al. Pregnancy outcomes after peripheral blood or bone marrow transplantation: a retrospective study. Lancet 2001; 358: 271276.Google Scholar
Callis, L, Nieto, J, Vila, A, Rende, J. Chlorambucil treatment in minimal lesion nephrotic syndrome: a reappraisal of its gonadal toxicity. Journal of Pediatrics 1980; 97: 653656.Google Scholar
Freckman, HA, Fry, HL, Mendez, FL et al. Chlorambucil–prednisolone therapy for disseminated breast carcinoma. Journal of the American Medical Society 1964; 189: 2326.Google Scholar
Chemaitilly, W, Mertens, AC, Mitby, P et al. Acute ovarian failure in the Childhood Cancer Survivor Study. Journal of Clinical Endocrinology and Metabolism 2006; 91: 17231728.Google Scholar
Pye, S, Cortes, J, Ault, P et al. The effects of imatinib on pregnancy outcome. Blood 2008; 111: 55055508.Google Scholar
Christopoulos, C, Dimakopoulou, V, Rotas, E. Primary ovarian insufficiency associated with imatinib therapy. New England Journal of Medicine 2008; 358: 10791080.Google Scholar
Meirow, D, Dor, J. Epidemiology and infertility in cancer patients. In Tulandi, T, Gosden, R (eds) Preservation of Fertility. London:Taylor and Francis; 2004: 2138.Google Scholar
Chakravarty, E, Murray, E, Kelman, A et al. Pregnancy outcomes after maternal exposure to rituximab. Blood 2011; 117: 14991506.Google Scholar
Dann, EJ, Epelbaum, R, Avivi, I et al. Fertility and ovarian function are preserved in women treated with an intensified regimen of cyclophosphamide, adriamycin, vincristine and prednisone (Mega-CHOP) for non-Hodgkin lymphoma. Human Reproduction 2005; 20; 22472249.Google Scholar
Meirow, D. Reproduction post-chemotherapy in young cancer patients. Molecular Cell Endocrinology 2000; 169: 123131.Google Scholar
Steffens, M, Beauloye, V, Brichard, B et al. Endocrine and metabolic disorders in young adult survivors of childhood acute lymphoblastic leukemia (ALL) or non-Hodgkin lymphoma (NHL). Clinical Endocrinology 2008; 69: 819827.Google Scholar
Huakvik, UKH, Dieset, I, Bjoro, T, Holte, H, Fossa, SD. Treatment-related premature ovarian failure as a long-term complication after Hodgkin’s lymphoma. Annals of Oncology 2006; 17: 14281433.CrossRefGoogle Scholar
Cabañas-Perianes, V, Macizo, M, Salido, E et al. Management of multiple myeloma during pregnancy: a case report and review. Hematological Oncology 2016; 34(2): 108114.Google Scholar
Green, DM, Whitton, JA, Stovall, M et al. Pregnancy outcomes in female survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. American Journal of Obstetrics and Gynecology 2002; 187: 10701080.Google Scholar
Winther, JW, Olsen, JH, Wu, H et al. Genetic disease in the children of Danish surviors of childhood and adolescent cancer. Journal of Clinical Oncology 2012; 30: 2733.CrossRefGoogle Scholar
Signorello, LB, Mulvihill, JJ, Green, DM et al. Congenital anomalies in the children of cancer survivors: a report from the childhood cancer survivor study. Journal of Clinical Oncology 2012; 30: 239245.Google Scholar
Bachanova, V, Connors, JM. Hodkgin lymphoma in pregnancy. Current Hematologic Malignancy Reports 2013; 8: 211217.Google Scholar
Ali, S, Jones, GL, Culligan, DJ et al. Guidelines for the management of acute myelod leukemia in pregnancy. British Journal of Haematology 2015; 170: 487495.Google Scholar
Eyre, TA, Lau, IJ, Mackillop, L, Collins, GP. Classical Hodgkins lymphoma and pregnancy. British Journal of Haematology 2015; 69: 613630.Google Scholar
Royal College of Physicians, Royal College of Radiologists and RCOG. The Effects of Cancer Treatment on Reproductive Function. Guidance on Management. London: RCP; 2007.Google Scholar
NICE. NICE Clinical Guideline 156. Fertility: Assessment and Treatment for People with Fertility Problems; 2013. https://www.nice.org.ukGoogle Scholar
The Ethics Committee of the American Society for Reproductive Medicine. Fertility preservation and reproduction in patients facing gonadotoxic therapies: a committee opinion. Fertility and Sterility 2013; 100: 12241231.Google Scholar
Loren, AW, Mangu, PB, Beck, LN et al. Fertility preservation for patients with cancer: American Society of Clinical Oncology Clinical Practice Guideline Update. Journal of Clinical Oncology 2013; 31: 25002510.Google Scholar
Cakmak, H, Katz, A, Cedars, MI, Rosen, MP. Effective method for emergency fertility preservation: random-start controlled ovarian stimulation. Fertility and Sterility 2013; 100: 16731680.CrossRefGoogle ScholarPubMed
Kuang, Y, Hong, Q, Chen, Q et al. Luteal-phase ovarian stimulation is feasible for producing competent oocytes in women undergoing in vitro fertilization/intracytoplasmic sperm injection treatment, with optimal pregnancy outcomes in frozen-thawed embryo transfer cycles. Fertility and Sterility 2014; 101: 105111.Google Scholar
Donnez, J, Dolmans, M, Pellicer, A et al. Restoration of ovarian activity and pregnancy after transplantation of cryopreserved ovarian tissue: a review of 60 cases of reimplantation. Fertility and Sterility 2013; 99: 15031513.Google Scholar
Dolmans, M, Marinescu, C, Saussoy, P et al. Reimplantation of cryopreserved ovarian tissue from patients with acute lymphoblastic leukemia is potentially unsafe. Blood 2010; 116: 29082914.Google Scholar
Rosendahl, M, Greve, T, Anderson, CY. The safety of transplanting cryopreserved ovarian tissue in cancer patients: a review of the literature. Journal of Assisted Reproduction and Genetics 2012; 30: 1124.Google Scholar
Lockwood, GM. Whose embryos are they anyway? Clinical Ethics 2007; 2: 5658.Google Scholar
Meirow, D, Dor, J. Epidemiology and infertility in cancer patients. In Tulandi, T, Gosden, R (eds) Preservation of Fertility. London:Taylor and Francis; 2004: 31.Google Scholar

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