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Chapter 43 - Ulcerative Colitis in Pregnancy

from Section 7 - Hepato-Renal and Gastrointestinal Conditions in Pregnancy

Published online by Cambridge University Press:  23 February 2023

By
Talat Bessissow ,
Amira El-Messidi  and
Cynthia H. Seow
Edited by
Amira El-Messidi  and
Alan D. Cameron
Amira El-Messidi
Affiliation:
McGill University, Montréal
Alan D. Cameron
Affiliation:
University of Glasgow
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Summary

A 30-year-old nulligravida with ulcerative colitis (UC) is referred by her primary care provider to your hospital center’s high-risk obstetrics unit for preconceptional counseling.

Keywords

Inflammatory bowel disease, ulcerative colitis, pregnancyPreconception counselingFertilityPerinatal risks, complications, maternal-fetal morbidity, adverse outcomeInvestigations, serum, stool, endoscopy, sigmoidoscopyPharmacology, therapeutics, treatment, mesalamine, tofacitinib, sulfasalazineGenetic risksAntenatal disease flare, managementObstetric deliveryContraception
Type
Chapter
Information
OSCEs in Obstetrics and Maternal-Fetal Medicine
An Evidence-Based Approach
 , pp. 553 - 562
Publisher: Cambridge University Press
Print publication year: 2023

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References

Suggested Readings

Bressler, B, Marshall, JK, Bernstein, CN, et al. Clinical practice guidelines for the medical management of nonhospitalized ulcerative colitis: the Toronto consensus. Gastroenterology. 2015;148(5):1035–1058.CrossRefGoogle ScholarPubMed
De Lima, A, Zelinkova, Z, Mulders, AG, et al. Preconception care reduces relapse of inflammatory bowel disease during pregnancy. Clin Gastroenterol Hepatol. 2016; 14:1285–1292.CrossRefGoogle ScholarPubMed
Magro, F, Gionchetti, P, Eliakim, R, et al. Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, diagnosis, extra-intestinal manifestations, pregnancy, cancer surveillance, surgery, and ileo-anal pouch disorders. J Crohns Colitis. 2017;11(6):649–670.CrossRefGoogle ScholarPubMed
Mahadevan, U, Robinson, C, Bernasko, N, et al. Inflammatory bowel disease in pregnancy clinical care pathway: a report from the American Gastroenterological Association IBD Parenthood Project Working Group. Am J Obstet Gynecol. 2019;220(4):308–323.Google Scholar
Nielsen, OH, Gubatan, JM, Juhl, CB, et al. Biologics for inflammatory bowel disease and their safety in pregnancy: a systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2020;S1542–3565(20):31281–31287.Google Scholar
Nguyen, GC, Seow, CH, Maxwell, C, et al. The Toronto Consensus Statements for the management of inflammatory bowel disease in pregnancy. Gastroenterology. 2016;150(3):734–757.Google Scholar
Picardo, S, Seow, CH. A pharmacological approach to managing inflammatory bowel disease during conception, pregnancy and breastfeeding: biologic and oral small molecule therapy. Drugs. 2019;79(10):1053–1063.CrossRefGoogle ScholarPubMed
Singh, S, Picardo, S, Seow, CH. Management of inflammatory bowel diseases in special populations: obese, old, or obstetric. Clin Gastroenterol Hepatol. 2020;18(6):1367–1380.CrossRefGoogle ScholarPubMed
Tandon, P, Leung, K, Yusuf, A, et al. Noninvasive methods for assessing inflammatory bowel disease activity in pregnancy: a systematic review. J Clin Gastroenterol. 2019; 53(8):574–581.CrossRefGoogle ScholarPubMed
van der Woude, CJ, Ardizzone, S, Bengtson, MB, et al. The second European evidence-based consensus on reproduction and pregnancy in inflammatory bowel disease. J Crohns Colitis. 2015;9(2):107–124.CrossRefGoogle ScholarPubMed

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