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Chapter 2.6 - Varicella-Zoster Virus-Related: Cytomegalovirus (CMV) and Herpes Infections

from 2 - Infectious and Postinfectious Vasculitis

Published online by Cambridge University Press:  06 October 2022

Anita Arsovska
By
Asma Akbar Ladak  and
Mohammad Wasay
Edited by
Derya Uluduz
Anita Arsovska
Affiliation:
University of Ss Cyril and Methodius
Derya Uluduz
Affiliation:
Istanbul Üniversitesi
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Summary

We present the case of a 36-year old male who presented with generalized tonic-clonic seizures and history of diffuse vesicular rash. In the ER, he was drowsy and disoriented with right hemiparesis. Investigations revealed IgG varicella antibodies in the CSF along with elevated homocysteine levels. MRV revealed extensive CVST in superficial sagittal sinus, right transverse sinus and superficial veins. He was treated with IV acyclovir, adequate hydration and was started on levetiracetam. He was put on low molecular weight heparin and continued on anticoagulation for 3 months. Follow up MRI showed recanalization of venous sinuses with no lesions. CVST secondary to VZV is a rare occurrence. We propose a diagnostic and treatment algorithm with our case

Keywords

Varicella zoster meningoencephalitisskin lesionsthrombotic complicationshomocysteineadequate hydration
Type
Chapter
Information
Rare Causes of Stroke
A Handbook
 , pp. 137 - 140
Publisher: Cambridge University Press
Print publication year: 2022

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References

Gilden, D, Cohrs, RJ, Mahalingam, R, Nagel, MA. Varicella zoster virus vasculopathies: diverse clinical manifestations, laboratory features, pathogenesis, and treatment. Lancet Neurol. 2009;8(8): 731–740.CrossRefGoogle ScholarPubMed
Patel, U, Ranjan, R, Agrawal, C, Patel, N. Primary varicella zoster infection presented with cerebral venous sinus thrombosis in adult. Int J Health Sci Res. 2015;5: 568–572.Google Scholar
Siddiqi, SA, Nishat, S, Kanwar, D, et al. Cerebral venous sinus thrombosis: Association with primary varicella zoster virus infection. J Stroke Cerebrovasc Dis. 2012;21(8): 917.e1–917.e4.Google Scholar
Khan, R, Yasmeen, A, Pandey, AK, Al Saffar, K, Narayanan, SR. Cerebral venous thrombosis and acute pulmonary embolism following varicella infection. Eur J Case Rep Intern Med. 2019;6(10): 001171.Google ScholarPubMed
Gayathri, K, Ramalingam, P, Santhakumar, R, et al. Cerebral sinus venous thrombosis as a rare complication of primary varicella zoster virus infection. J Assoc Physicians India. 2016;64(7): 74–76.Google ScholarPubMed
Sudhaker, B, Dnyaneshwar, MP, Jaidip, CR, Rao, SM. Cerebral venous sinus thrombosis (CVST) secondary to varicella induced hypercoagulable state in an adult. Intern Med Inside. 2014;2: 1.Google Scholar

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