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Focal segmental glomerulosclerosis in patients after Fontan operation: is this a Fontan-associated renal disease?

Published online by Cambridge University Press:  15 September 2021

Takashi Furuta Open the ORCID record for Takashi Furuta [Opens in a new window] ,
Jun Muneuchi Open the ORCID record for Jun Muneuchi [Opens in a new window] ,
Yuichiro Sugitani  and
Miwa Yoshino
Takashi Furuta
Affiliation:
Department of Pediatrics, Kyushu Hospital, Japan Community Healthcare Organization, Kitakyushu, Japan
Jun Muneuchi*
Affiliation:
Department of Pediatrics, Kyushu Hospital, Japan Community Healthcare Organization, Kitakyushu, Japan
Yuichiro Sugitani
Affiliation:
Department of Pediatrics, Kyushu Hospital, Japan Community Healthcare Organization, Kitakyushu, Japan
Miwa Yoshino
Affiliation:
Department of Pediatrics, Kyushu Hospital, Japan Community Healthcare Organization, Kitakyushu, Japan
*
Author for correspondence: Jun Muneuchi, MD, Department of Pediatrics, Kyushu Hospital Japan Community Healthcare Organization, 1-8-2, Kishionura, Yahatanishi-ku, Kitakyushu, Fukuoka 806-8507, Japan. Tel: +81 93 641 5111; Fax: +81 93 642 1868. E-mail: jmune@msn.com
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Abstract

Despite acceptable survival for Fontan operation, there are concerns about late complications affecting the major organs. We herein present two cases of adults after Fontan operation who developed focal segmental glomerulosclerosis. These cases suggest that focal segmental glomerulosclerosis is owing to haemodynamic incompetence associated with Fontan operation, including congestion, hypoxia, and hyperviscosity, which may be called Fontan-associated renal disease.

Keywords

CHDFontan operationfocal segmental glomerulosclerosismesangial proliferative glomerulonephritis
Type
Brief Report
Information
Cardiology in the Young , Volume 32 , Issue 5 , May 2022 , pp. 837 - 839
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Copyright
© The Author(s), 2021. Published by Cambridge University Press

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