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The role and efficacy of routine high-sensitivity troponin T screening in paediatric COVID-19

Part of: Echocardiography

Published online by Cambridge University Press:  06 January 2022

Mehmet G. Ramoğlu Open the ORCID record for Mehmet G. Ramoğlu [Opens in a new window] ,
Selen Karagözlü Open the ORCID record for Selen Karagözlü [Opens in a new window] ,
Özlem Bayram Open the ORCID record for Özlem Bayram [Opens in a new window] ,
Jeyhun Bakhtiyarzada Open the ORCID record for Jeyhun Bakhtiyarzada [Opens in a new window] ,
Alperen Aydın Open the ORCID record for Alperen Aydın [Opens in a new window] ,
Göksel Vatansever Open the ORCID record for Göksel Vatansever [Opens in a new window] ,
Halil Özdemir Open the ORCID record for Halil Özdemir [Opens in a new window] ,
Deniz Tekin Open the ORCID record for Deniz Tekin [Opens in a new window] ,
Tayfun Uçar Open the ORCID record for Tayfun Uçar [Opens in a new window]  and
Ergin Çiftçi Open the ORCID record for Ergin Çiftçi [Opens in a new window]
...Show all authors
Mehmet G. Ramoğlu
Affiliation:
Department of Pediatric Cardiology, Ankara University, School of Medicine, Ankara, Turkey
Selen Karagözlü
Affiliation:
Department of Pediatric Cardiology, Ankara University, School of Medicine, Ankara, Turkey
Özlem Bayram
Affiliation:
Department of Pediatric Cardiology, Ankara University, School of Medicine, Ankara, Turkey
Jeyhun Bakhtiyarzada
Affiliation:
Department of Pediatric Cardiology, Ankara University, School of Medicine, Ankara, Turkey
Alperen Aydın
Affiliation:
Department of Pediatric Cardiology, Ankara University, School of Medicine, Ankara, Turkey
Göksel Vatansever
Affiliation:
Department of Pediatric Emergency Medicine, Ankara University, School of Medicine, Ankara, Turkey
Halil Özdemir
Affiliation:
Department of Pediatric Infectious Diseases, Ankara University, School of Medicine, Ankara, Turkey
Deniz Tekin
Affiliation:
Department of Pediatric Emergency Medicine, Ankara University, School of Medicine, Ankara, Turkey
Tayfun Uçar
Affiliation:
Department of Pediatric Cardiology, Ankara University, School of Medicine, Ankara, Turkey
Ergin Çiftçi
Affiliation:
Department of Pediatric Infectious Diseases, Ankara University, School of Medicine, Ankara, Turkey
Ercan Tutar*
Affiliation:
Department of Pediatric Cardiology, Ankara University, School of Medicine, Ankara, Turkey
*
Author for correspondence: Prof Dr E. Tutar, Ankara Üniversitesi Tıp Fakültesi Hastanesi, Tıp Fakültesi Caddesi, Cebeci/Çankaya, Ankara 06590, Türkiye. Tel: +905323451201; Fax: +903123106371. E-mail: ercantutar@gmail.com
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Abstract

Objective:

We aimed to evaluate the efficacy and role of high-sensitivity troponin T in children with a confirmed SARS-CoV-2 infection and also the correlation of troponin T levels with symptoms, and echocardiographic findings were analysed.

Methods:

Two hundred and fourteen patients with a confirmed SARS-CoV-2 infection between the dates of 28 March and 15 August 2020 were enrolled in this retrospective single-centre study. Patients with comorbidities and diagnosed as multisystem inflammatory syndrome in children were excluded. Demographic data, clinical and laboratory parameters were evaluated. The patients were classified and compared according to the troponin positivity. The correlation of troponin T with symptoms and echocardiographic findings was analysed.

Results:

The most common symptoms in the whole study group were fever (53.3%) and cough (24.8%). Troponin T levels were elevated in 15 (7%) patients. The most common symptom in patients with troponin positivity was also fever (73.3%). Troponin T positivity was significantly higher in patients under the age of 12 months and troponin T levels were negatively correlated with age. C-reactive protein levels were elevated in 77 (36%) of the patients in the whole group and 7 (46.7%) of 15 patients with troponin positivity. C-reactive protein levels were similar between groups.

Conclusion:

Routine troponin screening does not yield much information in previously healthy paediatric COVID-19 patients without any sign of myocardial dysfunction. Elevated troponin levels may be observed but it is mostly a sign of myocardial injury without detectable myocardial dysfunction in this group of patients.

Keywords

COVID-19C-reactive proteinpaediatricmyocardial dysfunctiontroponin T
Type
Original Article
Information
Cardiology in the Young , Volume 32 , Issue 3 , March 2022 , pp. 472 - 476
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Copyright
© The Author(s), 2022. Published by Cambridge University Press

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Footnotes

*

The online version of this article has been updated since original publication. A notice detailing the change has also been published

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