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Modelos de prescripción de antidepresivos en Europa: Resultados del estudio de los Factores que Influyen en la Investigación de los Criterios de Valoración de la Depresión (FINDER)

Published online by Cambridge University Press:  01 May 2008

Michael Bauer ,
Brigitta U. Monz ,
Angel L. Montejo ,
Deborah Quail ,
Nicolas Dantcheve ,
Koen Demyttenaere ,
Ana García-Cebrián ,
Luigi Grassi ,
David G.S. Perahia  and
Catherine Reed
...Show all authors
Michael Bauer
Affiliation:
Departamento de Psiquiatría y Psicoterapia, Hospital Universitario Carl Gustav Carus, Technische Universitat Dresde, Fetscherstrabe 74, D 01307Dresde, Alemania
Brigitta U. Monz
Affiliation:
Boeliringer Ingelheim GmbH, D 55216 Ingelheim, Alemania
Angel L. Montejo
Affiliation:
Hospital Universitario de Salamanca, Avda. Comuneros 27, Salamanca37003, España
Deborah Quail
Affiliation:
Eli Lilly and Company, Centro de Investigación Lilly, Wood Manor, Sunninhill Road, Windlesham, SurreyGU20 6PH, Reino Unido
Nicolas Dantcheve
Affiliation:
Unidad de Psiquiatría, Hôtel-Dieu, 1 Place du Parvis Notre Dame, 75004 París, Francia
Koen Demyttenaere
Affiliation:
Universitair Ziekenhuis Gasthuisberg Herestraat 49, 3000 Leuven, Bélgica
Ana García-Cebrián
Affiliation:
Sección de Psiquiatría, Universidad de Ferrara, Corso Giovecca 203, 44100 Ferrara, Italia
Luigi Grassi
Affiliation:
Hospital Gordon, Bloomburg Street, LondresSW1V 2RH, Reino Unido
David G.S. Perahia
Affiliation:
Sección de Salud Mental de Atención Primaria, Departamento de Investigación de la Población y Servicios Sociales, Instituto de Psiquiatría, Parque De Crespigny, Denmark HUI, LondresSE5 8AF, Reino Unido
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Resumen

Los modelos de prescripción de antidepresivos y los factores que influyen en la elección del antidepresivo para el tratamiento de la depresión se estudiaron en el estudio de los Factores que Influyen en la Investigación de los Criterios de Valoración de la Depresión (FINDER), un estudio prospectivo de observación realizado en 12 países europeos con 3.468 adultos sobre el comienzo de la medicación antidepresiva en el primer episodio de depresión o en un nuevo episodio de depresión recurrente. Los inhibidores selectivos de la recaptación de serotonina (ISRS) son los antidepresivos más prescritos más frecuentemente (63,3% de los pacientes), seguidos de los inhibidores de la recaptación de serotonina-noradrenalina (IRSN, 13,6%), pero hubo una variación considerable entre los distintos países. Debemos destacar que se prescribieron antidepresivos tricíclicos y tetracíclicos (ATC) al 26,5% de los pacientes en Alemania. La elección del antidepresivo prescrito estaba bajo una influencia muy fuerte del uso anterior de antidepresivos, que se asoció considerablemente con la prescripción de un ISRS (CP 0,64; IC 95% 0,54, 0,76), un IRSN (CP 1,49; 1C 95% 1,18, 1,88) o una combinación de antidepresivos (CP 2,78; IC 95% 1,96, 3,96). Los factores del médico (edad, sexo, especialidad) y de los pacientes (gravedad de la depresión, edad, educación, tabaquismo, número de enfermedades físicas y síndromes funcionales actuales) se asociaron con la eleccción del antidepresivo inicial en algunos casos. Para concluir, la prescripción de antidepresivos varía en función del país, y el tipo de antidepresivo escogido está bajo la influencia de factores relacionados con el médico y con el paciente.

Keywords

AntidepresivosDepresiónEuropaFINDERPatrones de prescripción
Type
Artículo original
Information
European Psychiatry (Ed. Española) , Volume 15 , Issue 4 , May 2008 , pp. 167 - 175
Copyright
Copyright © European Psychiatric Association 2008

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