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2346 – Cocaine-induced Psychosis And Impulsivity In Cocaine-dependent Patients

Published online by Cambridge University Press:  15 April 2020

C. Roncero ,
L. Grau-López ,
C. Daigre ,
L. Rodriguez-Cintas ,
L. Miquel ,
N. Martínez-Luna ,
C. Barral ,
D. Bachiller ,
A. Egido  and
J. Alvarós
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C. Roncero
Affiliation:
Outpatient Drug Clinic Vall Hebron, Psychiatry Department, Hospital Vall Hebron-ASPB, Barcelona, Spain Psychiatry Department, Universidad Autónoma de Barcelona, Barcelona, Spain
L. Grau-López
Affiliation:
Outpatient Drug Clinic Vall Hebron, Psychiatry Department, Hospital Vall Hebron-ASPB, Barcelona, Spain
C. Daigre
Affiliation:
Outpatient Drug Clinic Vall Hebron, Psychiatry Department, Hospital Vall Hebron-ASPB, Barcelona, Spain
L. Rodriguez-Cintas
Affiliation:
Outpatient Drug Clinic Vall Hebron, Psychiatry Department, Hospital Vall Hebron-ASPB, Barcelona, Spain
L. Miquel
Affiliation:
Outpatient Drug Clinic Vall Hebron, Psychiatry Department, Hospital Vall Hebron-ASPB, Barcelona, Spain
N. Martínez-Luna
Affiliation:
Outpatient Drug Clinic Vall Hebron, Psychiatry Department, Hospital Vall Hebron-ASPB, Barcelona, Spain
C. Barral
Affiliation:
Outpatient Drug Clinic Vall Hebron, Psychiatry Department, Hospital Vall Hebron-ASPB, Barcelona, Spain
D. Bachiller
Affiliation:
Outpatient Drug Clinic Vall Hebron, Psychiatry Department, Hospital Vall Hebron-ASPB, Barcelona, Spain
A. Egido
Affiliation:
Outpatient Drug Clinic Vall Hebron, Psychiatry Department, Hospital Vall Hebron-ASPB, Barcelona, Spain
J. Alvarós
Affiliation:
Outpatient Drug Clinic Vall Hebron, Psychiatry Department, Hospital Vall Hebron-ASPB, Barcelona, Spain
C. Miguel
Affiliation:
Psychiatry Department, Universidad Autónoma de Barcelona, Barcelona, Spain Psychiatry Department, Hospital Vall Hebron, Barcelona, Spain

Abstract

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Introduction

Cocaine induced psychosis (CIP) is common but not developed in all cases. Many risk factors have been linked with CIP. A lifetime diagnosis of ADHD has been associated with the categorical presence of CIP.

Objectives

The objective of this study is to determinate the relationship between impulsivity and impulsivity-realetd disorders (BPD, BN and ADHD) and CIP.

Aims

We study the presence of psychotic symptoms using a clinical interview for psychotic symptoms in a large sample of cocaine-dependent patients. Patients suffering from schizophrenia or bipolar disorders were excluded. Finally we included 287 patients in the study.

Methods

A structured interview about psychotic symptoms were systematically conducted. The Structured Clinical Interview for DSM IV Axis I and Axis II disorders were used in order to identify the comorbidity. CAADID-II (Conners’ Adult ADHD Diagnostic Interview for DSM-IV) were used in order to identify ADHD comorbidity. Barrat impulsivity scale were used for evaluate impulsivity.

Results

BIS total were 63.78. We identify a significant association between CIP and BIS cognitive subscale p < 0.003 and BIS total p < 0.021. We also identify a significant association between CIP and adult ADHD in cocaine-dependent patients p < .0.002. We fail to identify association between CIP and BPD and BN.

Conclusions

CIP is related with BIS cognitive subscale and BIS total scores, and with ADHD comorbidity in cocaine-dependent patients. As well these findings could be useful for a clinical approach to the risks of psychotic states in cocaine-dependent patients.

Type
Abstract
Information
European Psychiatry , Volume 28 , Issue S1: Abstracts of the 21th European Congress of Psychiatry , 2013 , 28-E1475
Copyright
Copyright © European Psychiatric Association 2012
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