Hostname: page-component-cd9895bd7-p9bg8 Total loading time: 0 Render date: 2024-12-28T06:19:08.749Z Has data issue: false hasContentIssue false

Isolation of a novel cancer cachectic factor

Published online by Cambridge University Press:  28 February 2007

Michael J. Tisdale
Affiliation:
Pharmaceutical Sciences Institute, Aston University, Birmingham, B4 7ET
Rights & Permissions [Opens in a new window]

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Symposium on ‘New perspectives in the anorexia-cachexia syndrome’
Copyright
Copyright © The Nutrition Society 1997

References

REFERENCES

Bandyopadhyay, G. K., Imagawa, W., Wallace, D. R. & Nandi, S. (1988). Proliferative effects of insulin and epidermal growth factor on mouse mammary epithelial cells in primary culture. Enhancement by hydroxyeicosatetraenoic acids and synergism with prostaglandin E2. Journal of Biological Chemistry 263, 75677573.CrossRefGoogle ScholarPubMed
Beck, S. A., Groundwater, P., Barton, C. & Tisdale, M. J. (1990 a). Alterations in serum lipolytic activity of cancer patients with response to therapy. British Journal of Cancer 62, 822825.CrossRefGoogle ScholarPubMed
Beck, S. A., Mulligan, H. D. & Tisdale, M. J. (1990 b). Lipolytic factors associated with murine and human cancer cachexia. Journal of the National Cancer Institute 82, 19221926.CrossRefGoogle ScholarPubMed
Beck, S. A. & Tisdale, M. J. (1987). Production of lipolytic and proteolytic factors by a murine tumor-producing cachexia in the host. Cancer Research 47, 59195923.Google ScholarPubMed
Beck, S. A. & Tisdale, M. J. (1991). Lipid mobilising factors specifically associated with cancer cachexia. British Journal of Cancer 63, 846850.CrossRefGoogle ScholarPubMed
Belizario, J. E., Katz, M. & Raw, C. I. (1991). Bioactivity of skeletal muscle proteolysis-inducing factors in the plasma proteins from cancer patients with weight loss. British Journal of Cancer 63, 705710.CrossRefGoogle ScholarPubMed
Beutler, B., Greenwald, D., Hulmes, J. D., Chang, M., Pan, Y.-C. E., Mathison, J., Ulevitch, R. & Cerami, A. (1985). Identity of tumour necrosis factor and the macrophage-secreted factor cachectin. Nature 316, 552554.CrossRefGoogle ScholarPubMed
Bibby, M. C., Double, J. A., Ali, S. A., Fearon, K. C. H., Brennan, R. A. & Tisdale, M. J. (1987). Characterization of a transplantable adenocarcinoma of the mouse colon producing cachexia in recipient animals. Journal of the National Cancer Institute 78, 539546.Google ScholarPubMed
Cohn, S. H., Gartenhaus, W. & Sawitsky, A. (1981). Compartmental body composition of cancer patients with measurement of total body nitrogen, potassium and water. Metabolism 30, 222229.CrossRefGoogle ScholarPubMed
Costa, G. (1977). Cachexia, the metabolic component of neoplastic disease. Cancer Research 37, 23272335.Google Scholar
Costa, G. & Holland, J. F. (1966). Effects of Krebs-2 carcinoma on the lipid metabolism of male Swiss mice. Cancer Research 22, 10811083.Google Scholar
Costa, G., Lane, W. W., Vincint, R. G., Siebold, J. A., Aragon, M. & Bewley, P. T. (1980). Weight loss and cachexia in lung cancer. Nutrition and Cancer 2, 98103.CrossRefGoogle Scholar
Demetrakopoulos, G. E. V. & Brennan, M. F. (1982). Tumoricidal potential of nutritional manipulation. Cancer Research 42, Suppl., 756s761s.Google Scholar
De Wys, W. (1985). Management of cancer cachexia. Seminars in Oncology 12, 452460.Google ScholarPubMed
Evans, W. K., Makuch, R., Clamon, G. H., Feld, K., Weiner, R. S., Moran, E., Blum, R., Shepherd, F. E., Jeejeebhoy, K. N. & De Wys, W. D. (1985). Limited impact of total parenteral nutrition on nutritional status during treatment for small cell lung cancer. Cancer Research 45, 33473353.Google ScholarPubMed
Fearon, K. C. H., McMillan, D. C., Preston, T., Winstanley, P., Cruickshank, A. M. & Shenkin, A. (1991). Elevated circulating interleukin-6 is associated with an acute phase response but reduced fixed hepatic protein synthesis in patients with cancer. Annals of Surgery 213, 2631.CrossRefGoogle ScholarPubMed
Flores, E. A., Bistrian, B. R., Pomposelli, J. J., Dinarello, C. A., Blackburn, G. L. & Istfan, N. (1989). Infusion of tumor necrosis factor/cachectin promotes muscle catabolism in the rat. Journal of Clinical Investigation 83, 16141622.CrossRefGoogle ScholarPubMed
Garcia-Martinez, C., Lopez-Soriano, F. J. & Argiles, J. M. (1994). Interleukin-6 does not activate protein breakdown in rat skeletal muscle. Cancer Letters 76, 14.CrossRefGoogle Scholar
Glasgow, W. C. & Eling, T. E. (1990). Epidermal growth factor stimulates linoleic acid metabolism in BALB/c 3T3 fibroblasts. Molecular Pharmacology 38, 503510.Google ScholarPubMed
Goldberg, A., Kettelhut, K., Fagan, J. & Baracos, V. (1988). Activation of protein breakdown and prostaglandin E2 production in rat skeletal muscle fever is signaled by a macrophage product distinct from interleukin-1 or other known monokines. Journal of Clinical Investigation 81, 13781383.CrossRefGoogle ScholarPubMed
Grosvenor, M., Bulcavage, L. & Chlebowski, R. T. (1989). Symptoms potentially influencing weight loss in a cancer population. Cancer 63, 330335.3.0.CO;2-U>CrossRefGoogle Scholar
Groundwater, P., Beck, S. A., Barton, C., Adamson, C., Ferrier, I. N. & Tisdale, M. J. (1990). Alteration of serum and urinary lipolytic activity with weight loss in cachectic cancer patients. British Journal of Cancer 62, 816821.CrossRefGoogle ScholarPubMed
Kitada, S., Hays, E. F. & Mead, J. F. (1980). A lipid mobilizing factor in serum of tumour-bearing mice. Lipids 15, 168174.CrossRefGoogle Scholar
Loprinzi, C. L., Schaid, D. J., Dose, A. M., Burnham, N. L. & Jensen, M. D. (1993 b). Body composition changes in patients who gain weight while receiving megestrol acetate. Journal of Clinical Oncology 11, 152157.CrossRefGoogle ScholarPubMed
McDevitt, T. M., Todorov, P. T., Beck, S. A., Khan, S. H. & Tisdale, M. J. (1995). Purification and characterization of a lipid-mobilizing factor associated with cachexia-inducing tumors in mice and humans. Cancer Research 55, 14581463.Google ScholarPubMed
McMillan, D. C., Simpson, J. M., Preston, T., Watson, W., Fearon, K. C. H., Shenkin, A., Burns, H. J. G. & Mcardle, C. S. (1994). Effect of megestrol acetate on weight loss, body composition and blood screen of gastrointestinal cancer patients. Clinical Nutrition 13, 6975.CrossRefGoogle ScholarPubMed
Mahony, S. M., Beck, S. A. & Tisdale, M. J. (1988). Comparison of weight loss induced by recombinant tumour necrosis factor with that produced by a cachexia-inducing tumour. British Journal of Cancer 57, 385389.CrossRefGoogle ScholarPubMed
Masuno, H., Yamaskai, N. & Okuda, H. (1981). Purification and characterization of a lipolytic factor (toxohormone-L) from cell free fluid of ascites Sarcoma 180. Cancer Research 41, 284288.Google ScholarPubMed
Masuno, H., Yoshimura, H., Ogawa, N. & Okuda, H. (1984). Isolation of a lipolytic factor (toxohormone-L) from ascites fluid of patients with hepatoma and its effect on feeding behaviour. European Journal of Cancer and Clinical Oncology 20, 11771185.CrossRefGoogle Scholar
Oversen, L., Allingstrup, L., Hannibal, J., Mortensen, E. L. & Hansen, O. P. (1993). Effect of dietary counseling on food intake, body weight, response rate, survival and quality of life in cancer patients undergoing chemotherapy. A prospective, randomized study. Journal of Clinical Oncology 11, 20432048.CrossRefGoogle Scholar
Pfizer, L. I. & Regan, J. D. (1972). Basis for the serine requirement in leukemic and normal human leukocytes. Reduced levels of the enzymes in the phosphorylated pathway. Journal of the National Cancer Institute 48, 18971900.Google Scholar
Sauer, L. A. & Dauchy, R. T. (1987 a). Blood nutrient concentrations and tumor growth in vivo in rats: relationships during the onset of an acute fast. Cancer Research 47, 10651068.Google ScholarPubMed
Sauer, L. A. & Dauchy, R. T. (1987 b). Stimulation of tumor growth in adult rats in vivo during acute streptozotocin-induced diabetes. Cancer Research 47, 17561761.Google ScholarPubMed
Scagliotti, G. V., Gatti, E., Ferrari, G., Multi, L. & Pozzi, E. (1995). TNF-α determination in serum and pleural effusion in patients with lung cancer. International Journal of Oncology 6, 147151.Google ScholarPubMed
Smith, K. L. & Tisdale, M. J. (1993). Mechanism of muscle protein degradation in cancer cachexia. British Journal of Cancer 68, 314318.CrossRefGoogle ScholarPubMed
Socher, S. H., Martinez, D., Craig, J. B., Kuhn, J. G. & Oliff, A. (1988). Tumour necrosis factor not detectable in patients with clinical cancer cachexia. Journal of the National Cancer Institute 80, 595598.CrossRefGoogle Scholar
Tang, D. G., Chen, Y. O. & Honn, K. V. (1996). Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis. Proceedings of the National Academy of Sciences USA 93, 52415246.CrossRefGoogle ScholarPubMed
Taylor, D. D., Gercel-Taylor, C., Jenio, L. G. & Devereux, D. (1992). Identification of a human tumor-derived lipolysis-promoting factor. Cancer Research 52, 829834.Google ScholarPubMed
Thompson, M. P., Cooper, S. T., Parry, B. R. & Tuckey, J. A. (1993). Increased expression of the mRNA for the hormone-sensitive lipase in adipose tissue of cancer patients. Biochimica et Biophysica Acta 1180, 236242.CrossRefGoogle ScholarPubMed
Tisdale, M. J. (1980). Effect of methionine replacement by homocysteine on the growth of cells. Cell Biology International Report 4, 563567.CrossRefGoogle ScholarPubMed
Tisdale, M. J. & Beck, S. A. (1991). Inhibition of tumour-induced lipolysis in vitro and cachexia and tumour growth in vivo by eicosapentaenoic acid. Biochemical Pharmacology 41, 103107.CrossRefGoogle ScholarPubMed
Todorov, P., Cariuk, P., McDevitt, T., Coles, B., Fearon, K. & Tisdale, M. (1996 a). Characterization of a cancer cachectic factor. Nature 379, 739742.CrossRefGoogle ScholarPubMed
Todorov, P. T., McDevitt, T. M., Cariuk, P., Coles, B., Deacon, M. & Tisdale, M. J. (1996 b). Induction of muscle protein degradation and weight loss by a tumour product. Cancer Research 56, 12561261.Google ScholarPubMed
Uren, J. R. & Lazarus, H. (1979). L-Cyst(e)ine requirements of malignant cells and progress towards depletion therapy. Cancer Treatment Reports 63, 10731079.Google Scholar
Wigmore, S. J., Ross, J. A., Falconer, J. S., Plester, C. E., Tisdale, M. J., Carter, D. C. & Fearon, K. C. H. (1996). The effect of polyunsaturated fatty acids on the progress of cachexia in patients with pancreatic cancer. Nutrition 12, S27S30.CrossRefGoogle ScholarPubMed