We solve several multi-parameter families of binomial Thue equations of arbitrary degree; for example, we solve the equation
$${{5}^{u}}{{x}^{n}}-{{2}^{r}}{{3}^{5}}{{y}^{n}}=\pm 1,$$
in non-zero integers $x,y$ and positive integers $u,r,s$ and $n\ge 3$. Our approach uses several Frey curves simultaneously, Galois representations and level-lowering, new lower bounds for linear forms in 3 logarithms due to Mignotte and a famous theorem of Bennett on binomial Thue equations.