We evaluated herbicide treatments for control of umbrella dracaena, locally invasive in central Florida. Biannual treatments of imazapyr (3.2 and 6.4 g ai L−1), metsulfuron (0.08 and 0.16 g ai L−1), and imazapyr (0.8 g ai L−1) plus glyphosate (19.9 g ai L−1) reduced cover to < 3% at 12 mo, but no treatment eliminated the plant. In contrast, a single treatment on individual potted plants in greenhouse trials was highly effective with ≥ 98% necrosis/chlorosis at 6 mo and no regrowth at 9 mo posttreatment for most treatments. Management of umbrella dracaena will require more than two herbicide treatments with imazapyr, metsulfuron, glyphosate, or a combination of these herbicides if eradication is to be achieved. Because it is currently problematic and localized in one specific area in about 40 ha, it should be a high management priority before it spreads throughout Florida and possibly other states.