The purpose of this paper is to analyse the significance of the human element in accidents involving Greek-flagged ships, during 1993–2006, worldwide. In this context, the human element as a general factor of accident initiation and most importantly its constituent components, in the form of specific onboard duties (functions) and/or off-board (mainly ashore) entities, were presented and analysed. It was found that 57·1% of all accidents were attributed to the human element, whereas 75·8% of the latter were detected onboard and 80·4% of the onboard human-induced accidents were linked to errors and violations of the ship's master. Furthermore, since the timeframe examined covers the implementation of the ISM Code, the current analysis was aimed at producing valuable information with regard to its effectiveness upon Greek shipping. In this respect, a 12·2% reduction of human-caused accidents has been found during the post-ISM period. Finally, the association between specific accident types and human element components was examined utilising the technique of correspondence analysis and it was found that groundings and collisions were closely related to the ship's Master, whereas mechanical failures and fires were associated with the engine officers, and cargo shifts and flooding with bridge officers.