This contribution analyses the EU’s new data acts. Interoperability is a common denominator of the EU’s new data acts. This paper demonstrates that the new data acts provide various approaches or concepts of collaborative governance to regulate interoperability. Although the EU’s new data acts are far from a uniform governance concept, we detected certain institutional arrangements organising the collaboration between private self-regulatory bodies, other private stakeholders and public bodies to lay down rules for interoperability.

The personalised oncology paradigm remains challenging to deliver despite technological advances in genomics-based identification of actionable variants combined with the increasing focus of drug development on these specific targets. To ensure we continue to build concerted momentum to improve outcomes across all cancer types, financial, technological and operational barriers need to be addressed. For example, complete integration and certification of the ‘molecular tumour board’ into ‘standard of care’ ensures a unified clinical decision pathway that both counteracts fragmentation and is the cornerstone of evidence-based delivery inside and outside of a research setting. Generally, integrated delivery has been restricted to specific (common) cancer types either within major cancer centres or small regional networks. Here, we focus on solutions in real-world integration of genomics, pathology, surgery, oncological treatments, data from clinical source systems and analysis of whole-body imaging as digital data that can facilitate cost-effectiveness analysis, clinical trial recruitment, and outcome assessment. This urgent imperative for cancer also extends across the early diagnosis and adjuvant treatment interventions, individualised cancer vaccines, immune cell therapies, personalised synthetic lethal therapeutics and cancer screening and prevention. Oncology care systems worldwide require proactive step-changes in solutions that include inter-operative digital working that can solve patient centred challenges to ensure inclusive, quality, sustainable, fair and cost-effective adoption and efficient delivery. Here we highlight workforce, technical, clinical, regulatory and economic challenges that prevent the implementation of precision oncology at scale, and offer a systematic roadmap of integrated solutions for standard of care based on minimal essential digital tools. These include unified decision support tools, quality control, data flows within an ethical and legal data framework, training and certification, monitoring and feedback. Bridging the technical, operational, regulatory and economic gaps demands the joint actions from public and industry stakeholders across national and global boundaries.

Within the last decade, online sustainability knowledge-action platforms have proliferated. We surveyed 198 sustainability-oriented sites and conducted a review of 41 knowledge-action platforms, which we define as digital tools that advance sustainability through organized activities and knowledge dissemination. We analyzed platform structure and functionality through a systematic coding process based on key issues identified in three bodies of literature: (a) the emergence of digital platforms, (b) the localization of the sustainable development goals (SDGs), and (c) the importance of multi-level governance to sustainability action. While online collaborative tools offer an array of resources, our analysis indicates that they struggle to provide context-sensitivity and higher-level analysis of the trade-offs and synergies between sustainability actions. SDG localization adds another layer of complexity where multi-level governance, actor, and institutional priorities may generate tensions as well as opportunities for intra- and cross-sectoral alignment. On the basis of our analysis, we advocate for the development of integrative open-source and dynamic global online data management tools that would enable the monitoring of progress and facilitate peer-to-peer exchange of ideas and experience among local government, community, and business stakeholders. We argue that by showcasing and exemplifying local actions, an integrative platform that leverages existing content from multiple extant platforms through effective data interoperability can provide additional functionality and significantly empower local actors to accelerate local to global actions, while also complex system change.

No matter how good a smart device may be, it remains useless outside the context of a digital ecosystem. Internet of Things (IoT) environments are possible as long as services and products can interconnect smoothly and exchange data in real time. Therefore, interoperability ranks high in global policy agendas, with the promise of bringing an end to network effects slanted in favour of ecosystem orchestrators. However, recent regulatory initiatives introducing interoperability obligations risk falling short of their intent or even risk generating unintended consequences in the absence of a coherent approach to standardisation. Against this backdrop, focusing on the UK Open Banking experience, this article makes a proposal for workable interoperability in IoT ecosystems aimed at ensuring market contestability without undermining incentives to innovate.

Today, technological developments are ever-growing yet fragmented. Alongside inconsistent digital approaches and attitudes across city administrations, such developments have made it difficult to reap the benefits of city digital twins. Bringing together experiences from five research projects, this paper discusses these digital twins based on two digital integration methodologies—systems and semantic integration. We revisit the nature of the underlying technologies, and their implications for interoperability and compatibility in the context of planning processes and smart urbanism. Semantic approaches present a new opportunity for bidirectional data flows that can inform both governance processes and technological systems to co-create, cross-pollinate, and support optimal outcomes. Building on this opportunity, we suggest that considering the technological dimension as a new addition to the trifecta of economic, environmental, and social sustainability goals that guide planning processes, can aid governments to address this conundrum of fragmentation, interoperability, and compatibility.

While many Latin American countries have a tradition of receiving migrants, including the countries selected as case studies, there are no institutionalized mechanisms for the integration and settlement of migrants. The objective of this article is to explore how to improve migration data collection and management in a region that does not have many migration integration policies in place. I assess the state of migration data collection and management in three case studies: the city of Cucuta in Colombia, the North Huetar Region in Costa Rica, and the city of Monterrey in Mexico. The three countries publish data exclusively at the national level, rather than the local or municipal. Despite all case studies having a variety of administrative data, mainly in the form of entries and exits by nationality, these data are not enough to properly identify the sociodemographic characteristics of migrant populations in a country, and much less in specific cities. I make recommendations divided into three main themes to improve migration data in Latin America.

This article explores the role of interoperability in the development of digital public services in Europe, analyzing the effects of an European Union (EU)-level initiative (the European interoperability framework, EIF) and the development of e-Government services on how citizens interact online with public administrations. The EIF is a common EU framework providing guidance on public sector interoperability. EU countries are not mandated to follow the EIF, but they are encouraged to take up its guidance in their respective national interoperability frameworks (NIFs). Against this background, this article tests two hypotheses: (a) the introduction of NIFs facilitates the online interaction between citizens and public administrations and (b) better e-Government services encourage citizens to interact online with public administrations. Both hypotheses are confirmed by a panel data analysis covering 26 European countries over the period 2012–2019. The analysis relies on a dummy variable reflecting the adoption of NIFs, built by carefully examining official documents of the countries in the scope of the analysis. Based on the empirical results, this article puts forward two main policy recommendations. First, efforts to improve e-Government services across Europe should be intensified in order to support the overarching digital agenda of the EU and increase benefits for European citizens. Second, interoperability should become a central element when designing new digital public services. Therefore, the European Commission could foster a common approach to interoperability of digital public services across the EU by strengthening the governance of interoperability initiatives and encouraging the adoption of specific interoperability requirements.

This paper introduces a dynamic knowledge-graph approach for digital twins and illustrates how this approach is by design naturally suited to realizing the vision of a Universal Digital Twin. The dynamic knowledge graph is implemented using technologies from the Semantic Web. It is composed of concepts and instances that are defined using ontologies, and of computational agents that operate on both the concepts and instances to update the dynamic knowledge graph. By construction, it is distributed, supports cross-domain interoperability, and ensures that data are connected, portable, discoverable, and queryable via a uniform interface. The knowledge graph includes the notions of a “base world” that describes the real world and that is maintained by agents that incorporate real-time data, and of “parallel worlds” that support the intelligent exploration of alternative designs without affecting the base world. Use cases are presented that demonstrate the ability of the dynamic knowledge graph to host geospatial and chemical data, control chemistry experiments, perform cross-domain simulations, and perform scenario analysis. The questions of how to make intelligent suggestions for alternative scenarios and how to ensure alignment between the scenarios considered by the knowledge graph and the goals of society are considered. Work to extend the dynamic knowledge graph to develop a digital twin of the UK to support the decarbonization of the energy system is discussed. Important directions for future research are highlighted.