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Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL): a familial cause of depression and headache
Killian O'Rourke, Niall Crumlish, Darra Murphy, John Stack, Brian Murray
Journal:

Irish Journal of Psychological Medicine / Volume 27 / Issue 4 / December 2010

Published online by Cambridge University Press:

13 June 2014, pp. 215-216

Print publication:

December 2010
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A 31 year-old man with a history of a depressive episode presented with acute severe ‘thunderclap’ headache. Magnetic resonance imaging (MRI) revealed abnormalities typical of cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL), which was subsequently confirmed by genetic analysis. The psychiatric features of this genetic cause of depression and headache are discussed.

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Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL): a familial cause of depression and headache