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Phobias, strong fears related to particular situations, are the most common anxiety problems. People often find a way to live with them in normal life, often by avoiding situations that trigger the fear. Pregnancy and the postnatal period makes this very difficult in the case of two particular phobias, fear of blood, injections and injury (BII) , and fear of vomiting. These situations are impossible to avoid completely at this time and can therefore be very distressing. Fear of vomiting is often related to early memories of this, and keeps going in the present by avoidance and taking particular precautions that keep the anxiety going. This chapter will help you understand and work through these factors to tackle your fears. BII is unique in triggering a fainting response and probably has a large genetic component rather than being learned. We describe proven techniques to apply during exposure exercises to counteract the fainting response triggered in BII, which are known to have a long-lasting effect. Getting on top of these fears will help you manage and enjoy pregnancy and the postnatal year.
The virtual environment with realistically rendered fear-inducing stimuli is enough to conduct VR exposure therapy (VRE), although the total control over the virtual environment also enables presentation of stimuli, contexts, and tasks not possible in in vivo exposure therapy (i.e. flight etc.)30 randomized controlled trials revealing high efficacy and effect sizes comparable of VRE-CBT to in vivo exposure therapy. Aerophobia is a very frequent limitation and affect 25% of the population and 30% of the subjects who fly make habitual use of anxiolytics.
Objectives
The aims of this study is to show that conducting VR exposure in CBT for simple phobia (flight phobia) is effective and is an efficacious treatment for fear and anxiety,Vs other treatments.
Methods
Participants (n = 39; age between 19 and 60 years) in the active arms received individual CBT VR exposure for six sessions and outcome was assessed with questionnaires: MSPS;Rathus Assertiveness Scale (RAS); HAM-A; QMAV; QSAV – (Flying fear); QoL INDEX and a behaviour avoidance test (really take the plane). Wilcoxon tests was using for the statistical analysis.
Results
36 subjects managed to take the plane at the end of treatment and the results obtained showed a significant difference between “before treatment (T0) and after (T1)” with the exception of the Rathus test. All the SF-36 scales show a significant difference between “before-after”. 3 subjects was dropped out
Conclusions
Using VR can be advantageous over standard CBT as a potential solution for treatment avoidance and as an efficient, cost-effective and practical medium of exposure.
This study examined factors influencing parent willingness to use D-Cycloserine (DCS) for treating child anxiety. N = 222 parents were given information about using DCS to treat anxiety. They were then asked to rate their willingness to allow their child to take DCS/antibiotics for mild anxiety, severe anxiety, or an infection. The associations between willingness to use DCS and parental trait anxiety, demographics, as well as specific concerns regarding the medication, were examined. Parents could also provide written responses regarding their attitudes to DCS, which were analysed for themes. Parents reported concerns regarding potential side-effects from DCS. More severe anxiety was associated with more willingness to consent; however, parents were more willing to use antibiotics to treat an infection than DCS to treat their child's anxiety. The degree of perceived benefit from DCS was most strongly associated with parents’ willingness to use it. Overall, parents expressed mixed views, reporting they would consider using DCS to treat their child; however, they had significant concerns about it. Results suggest providing parents with information explaining how DCS works, its risks and potential benefits may increase its acceptability.
This study aims to (i) estimate the prevalence of blood-injection-injury phobia (BIIP) diagnosed as present at any time during the life prior to the interview, with or without another Specific Phobia diagnosed as present during the 12 months prior to the interview, (ii) characterize types and frequencies of co-occurring fears, (iii) evaluate the association with chronic medical conditions and lifetime psychiatric comorbidity, and (iv) explore medical service use associations in a nationally representative sample of older adults.
Methods:
A sample of 8,205 older adults, aged 65 years or older, was derived from Wave 1 of the National Epidemiological Survey on Alcohol and Related Conditions (NESARC).
Results:
The weighted lifetime prevalence of BIIP with and without 12-month Specific Phobia was 0.6% (95% CI: 0.4–0.8) and 4.2% (95% CI: 3.7–4.8), respectively, and these two groups ranked similarly in terms of sociodemographic, health, and psychiatric characteristics. BIIP most frequently co-occurred with other lifetime fears, and was positively associated with hypertension and lifetime history of anxiety and personality disorders after controlling for sociodemographic and psychiatric confounders.
Conclusions:
Our findings suggest that lifetime BIIP may bear mental and physical health significance in older adults.
Hypothalamic-pituitary-adrenal axis functioning, with cortisol as its major output hormone, has been presumed to play a key role in the development of psychopathology. Predicting affective disorders from diurnal cortisol levels has been inconclusive, whereas the predictive value of stress-induced cortisol concentrations has not been studied before. The aim of this study was to predict mental disorders over a 3-year follow-up from awakening and stress-induced cortisol concentrations.
Method
Data were used from 561 TRAILS (TRacking Adolescents’ Individual Lives Survey) participants, a prospective cohort study of Dutch adolescents. Saliva samples were collected at awakening and half an hour later and during a social stress test at age 16. Mental disorders were assessed 3 years later with the Composite International Diagnostic Interview (CIDI).
Results
A lower cortisol awakening response (CAR) marginally significantly predicted new disorders [odds ratio (OR) 0.77, p = 0.06]. A flat recovery slope predicted disorders with a first onset after the experimental session (OR 1.27, p = 0.04). Recovery revealed smaller, non-significant ORs when predicting new onset affective or anxiety disorders, major depressive disorder, or dependence disorders in three separate models, corrected for all other new onsets.
Conclusions
Our results suggest that delayed recovery and possibly reduced CAR are indicators of a more general risk status and may be part of a common pathway to psychopathology. Delayed recovery suggests that individuals at risk for mental disorders perceived the social stress test as less controllable and less predictable.
Background: People with anxiety disorders occasionally report fears about losing control of basic bodily functions in public. These anxieties often occur in the absence of physical disorder and have previously been recognized as “obsessive” anxieties reflecting a preoccupation with loss of bowel/bladder control. Motivated by our observations of the non-trivial occurrence of such anxieties in our clinical practice we sought to fill a gap in the current understanding of “bowel/bladder-control anxieties”. Method: Eligible participants completed an internet survey. Results: Bowel/bladder-control anxieties (n = 140) tended to emerge in the mid to late 20s and were associated with high levels of avoidance and functional impairment. There was a high prevalence of panic attacks (78%); these were especially prevalent among those with bowel-control anxiety. Of those with panic attacks, 62% indicated that their main concern was being incontinent during a panic attack. Significantly, a proportion of respondents (~16%) reported actually being incontinent during a panic attack. Seventy percent of participants reported intrusive imagery related to loss of bowel/bladder control. Intrusion-related distress was correlated with agoraphobic avoidance and general role impairment. Some differences were noted between those with predominantly bowel-, predominantly bladder- and those with both bowel and bladder-control anxieties. Conclusion: This preliminary characterization indicates that even in a non-treatment seeking community sample, bowel/bladder-control anxieties are associated with high levels of distress and impairment. Further careful characterization of these anxieties will clarify their phenomenology and help us develop or modify treatment protocols in a way that takes account of any special characteristics of such viscerally-centred phobic syndromes.
Sleep benefits memory consolidation. Here, we tested the beneficial effect of sleep on memory consolidation following exposure psychotherapy of phobic anxiety.
Method
A total of 40 individuals afflicted with spider phobia according to DSM-IV underwent a one-session virtual reality exposure treatment and either slept for 90 min or stayed awake afterwards.
Results
Sleep following exposure therapy compared with wakefulness led to better reductions in self-reported fear (p = 0.045, d = 0.47) and catastrophic spider-related cognitions (p = 0.026, d = 0.53) during approaching a live spider, both tested after 1 week. Both reductions were associated with greater percentages of stage 2 sleep.
Conclusions
Our results indicate that sleep following successful psychotherapy, such as exposure therapy, improves therapeutic effectiveness, possibly by strengthening new non-fearful memory traces established during therapy. These findings offer an important non-invasive alternative to recent attempts to facilitate therapeutic memory extinction and consolidation processes with pharmacological or behavioral interventions.
A 35-year-old Middle Eastern woman, experiencing moderate depression compounded by animal phobia was referred to an Improving Access to Psychological Therapies (IAPT) service. Shared understandings were gradually developed using written functional analyses translated in session. Activity scheduling was integrated with graded exposure to increase access to positive reinforcement. Questionnaires and subjective data indicated a reduction in phobic avoidance and functioning increased. Despite the complexity of working as a triad, a positive therapeutic relationship was achieved with increased mutual cultural understanding. Indirect communication led to difficulties maintaining guided discovery and focus. There is limited evidence to support CBT when delivered through an interpreter. IAPT recommendations suggest staff reflect the community; the North East has one of the lowest foreign-born populations in the UK indicating that IAPT services may be ill prepared to work with ethnic minorities. Learning points for the therapist were: maintain simplicity, take time to formulate incorporation of cultural difference, and use transcultural interventions. The interpreter brought advantages; providing means of communication and understanding of cultural differences. Disadvantages were the potential for bias or lost information, increased time and complexity of delivering therapy. This case indicates a deficit in high intensity training and lack of literature to support therapists.
Background: Distressing visual hallucinations (VH) are frequently present in schizophrenia. Despite their prevalence, limited research exists regarding effective clinical interventions. Cognitive models of VH state that distress results from threat appraisals of the hallucination. Method: This individual case study describes the use of a graded exposure approach following the discovery of phobic anxiety associated with visual hallucinatory content. Treatment involved 20 sessions of individual cognitive behaviour therapy (CBT), of which 12 sessions focused on graded exposure. Results: A reduction in frequency of visions and associated distress was reported and these changes were maintained at a 3-month follow-up. Conclusions: The findings are consistent with the cognitive model of VH. Through exposure to the hallucinatory content, the client re-appraised her VH as non-threatening, and her fear of them reduced. This reduction in anxiety led to a decrease in the occurrence of the VH.
Co-morbidity of mood and anxiety disorders is common and often associated with greater illness severity. This study investigates clinical correlates and familiality of four anxiety disorders in a large sample of bipolar disorder (BP) and major depressive disorder (MDD) pedigrees.
Method
The sample comprised 566 BP families with 1416 affected subjects and 675 MDD families with 1726 affected subjects. Clinical characteristics and familiality of panic disorder, social phobia, specific phobia and obsessive-compulsive disorder (OCD) were examined in BP and MDD pedigrees with multivariate modeling using generalized estimating equations.
Results
Co-morbidity between mood and anxiety disorders was associated with several markers of clinical severity, including earlier age of onset, greater number of depressive episodes and higher prevalence of attempted suicide, when compared with mood disorder without co-morbid anxiety. Familial aggregation was found with co-morbid panic and OCD in both BP and MDD pedigrees. Specific phobia showed familial aggregation in both MDD and BP families, although the findings in BP were just short of statistical significance after adjusting for other anxiety co-morbidities. We found no evidence for familiality of social phobia.
Conclusions
Our findings suggest that co-morbidity of MDD and BP with specific anxiety disorders (OCD, panic disorder and specific phobia) is at least partly due to familial factors, which may be of relevance to both phenotypic and genetic studies of co-morbidity.
To explore the genetic and environmental factors underlying the co-occurrence of lifetime diagnoses of DSM-IV phobia.
Method
Female twins (n=1430) from the population-based Norwegian Institute of Public Health Twin Panel were assessed at personal interview for DSM-IV lifetime specific phobia, social phobia and agoraphobia. Comorbidity between the phobias were assessed by odds ratios (ORs) and polychoric correlations and multivariate twin models were fitted in Mx.
Results
Phenotypic correlations of lifetime phobia diagnoses ranged from 0.55 (agoraphobia and social phobia, OR 10.95) to 0.06 (animal phobia and social phobia, OR 1.21). In the best fitting twin model, which did not include shared environmental factors, heritability estimates for the phobias ranged from 0.43 to 0.63. Comorbidity between the phobias was accounted for by two common liability factors. The first loaded principally on animal phobia and did not influence the complex phobias (agoraphobia and social phobia). The second liability factor strongly influenced the complex phobias, but also loaded weak to moderate on all the other phobias. Blood phobia was mainly influenced by a specific genetic factor, which accounted for 51% of the total and 81% of the genetic variance.
Conclusions
Phobias are highly co-morbid and heritable. Our results suggest that the co-morbidity between phobias is best explained by two distinct liability factors rather than a single factor, as has been assumed in most previous multivariate twin analyses. One of these factors was specific to the simple phobias, while the other was more general. Blood phobia was mainly influenced by disorder specific genetic factors.
Common fears change over development. Genetic and environmental risk factors for fears are partly shared across fears and partly fear-specific. The nature of the changes in common and fear-specific genetic and environmental risk factors over time is unknown.
Method
Self-reported fears were obtained at ages 13–14, 16–17 and 19–20 from 2404 twins in the Swedish Twin Study of Child and Adolescent Development. A multivariate longitudinal twin analysis was conducted with Mx.
Results
Eighteen individual items formed four fear factors: animal, blood-injury, situational, and social. The best-fit model had no quantitative or qualitative sex effects or shared environmental effects, but included a strong common factor with a stable cross-time structure with highest loadings on situational and lowest loadings on social fears. New common and fear-specific genetic risk factors emerged over development. With increasing age, genetic effects declined in overall importance and became more fear-specific. Cross-time continuity in specific genetic effects was highest for animal and lowest for social fears. Social fears had a ‘burst’ of specific genetic effects in late adolescence. Individual-specific environmental factors impacted both on the general fear factor and on specific fears. Compared to genetic effects, the impact of the unique environment was more time-specific.
Conclusions
Genetic and environmental risk factors for individual fears are partly mediated through a common fear factor and are partly fear-specific in their effect. The developmental pattern of these risk factors is complex and dynamic with new common and specific genetic effects arising in late adolescence and early adulthood.
Evaluations of computer-guided CBT (CCBT) suggest that this is a promising approach to closing the gap between the demand for, and the supply of, CBT. However, additional studies are required that are conducted by researchers independent of the programme developers, and include a wider range of participants. This independent study examined the viability of CCBT for panic and phobic anxiety in an unselected sample of referrals in remote and rural areas of Scotland. Outcome was assessed by a wide range of outcome measures, completed before and after treatment, and at 4-month follow-up. Participants experienced few difficulties in using the programme, and GPs and participants regarded CCBT as acceptable and useful. Major improvements were obtained, with several large effect sizes, which remained at follow-up. It was concluded that computer-guided CBT can play a useful part in delivering CBT services in rural areas; and that self-help CBT may be the only treatment option available to some sufferers.
The present study was designed to test the hypothesis that blood fearful and nonfearful individuals would be differentiated by their pattern of recall of schematic and non-schematic prose material. Blood fearful (n=36) and nonfearful (n=40) individuals were presented with five prose passages describing harm or injury. Nine sentences in each passage described events representative of the schema content of most individuals, whereas six sentences in each passage described events that are not representative of typical schema content. Participants read passages that either described themselves experiencing the situations or described themselves witnessing others in the situations and completed a free recall task in both immediate (i.e. 2 minutes) and delayed (i.e. one week) recall conditions. Results did not replicate studies from the cognitive psychology literature on which this study was based. Instead, participants who read passages describing themselves in these situations recalled the gist of the material more accurately than participants who read passages in which they witnessed another individual in the situation. Blood fearful participants recalled the affective tone of neutral passages less accurately than nonfearful participants. Results suggest that activation of schema content has little influence on memory performance, although assessing the affective tone of recalled material detected subtle differences in memory performance between fearful and nonfearful groups.
A. Öhman and J.J.F. Soares (1994) demonstrated
that masked presentation of phobic pictures produces increased
skin conductance responses (SCRs) in phobic subjects. A.
Öhman (1993) explained this phenomenon in terms of
a hypothetical “feature detector” that identifies
physical characteristics of stimuli and activates the arousal
system without involving significance evaluation or consciousness.
By exposing spider phobics to spider words, general threat
words, and neutral words instead of pictures, this explanation
was tested. Words were presented both masked and unmasked
while electrodermal activity was measured. Under unmasked
conditions, SCRs were largest for spider words followed
by general threat words, then neutral words. When masked,
the difference between spider words and general threat
words disappeared but SCRs remained significantly smaller
for neutral words. It is concluded that activation of the
arousal system by masked threat cues does not necessarily
depend on their perceptual characteristics.
The discriminant validity of children's and parents' ratings of the child's fear on the Revised
Fear Survey Schedule for Children (FSSC-R; Ollendick, 1983) was examined using a clinic
sample of children who met DSM criteria for phobic disorders (N=120). Discriminant
function analyses and item analyses were conducted to determine if children meeting
diagnostic criteria for a primary disorder of social phobia, simple phobia of the dark/sleeping
alone, simple phobia of animals, or a simple phobia of shots/doctors could be differentiated
on the basis of FSSC-R subscale scores and items. Results of the discriminant function
analyses indicated that the child-completed as well as the parent-completed FSSC-Rs were
similarly useful in differentiating the specific types of phobias. Results of the item analyses
indicated that child-completed FSSC-R items could discriminate among the different simple
phobias but not social phobia and that parent-completed FSSC-R items could discriminate
not only the different simple phobias but also social phobia. Results are discussed in terms
of the utility of the FSSC-R in the assessment of clinically significant fears in children with
phobic disorders and the relative utility of child and parent ratings in the assessment of
childhood fears.
The temporal course of startle reflex modulation
and autonomic response patterns to fear-relevant and fear-irrelevant
pictures in subjects with high and low levels of animal
fear was investigated. Thirty-eight high-fear and 48 low-fear
volunteers viewed photos of snakes and spiders and pictures
of neutral and pleasant content. The slides were presented
for 6 s or for only 150 ms, depending on the group. Acoustic
startle probes were presented at five different times after
slide onset. Relative potentiation of the startle responses
started 300 ms after onset of snake/spider pictures in
fearful subjects. This fear-potentiated startle effect
was maintained for the later probe times and was identical
in the 150-ms condition. Fear-relevant pictures also prompted
a sympathetically dominated autonomic response profile
in fearful persons. These data support the idea that fear
can be activated very rapidly, requiring only minimal stimulus
input.
Doll phobia is a rare phobia that has only been reported twice in the literature, both times in male patients. The following case is the first to be described in a female patient. The characteristics of the dolls that caused most fear in all three cases are compared and the possibility that this indicates a similar genesis of the phobia that could be explored by psychodynamic psychotherapy is discussed. A Hellenic derivation of doll phobia for future use is suggested.
Cette étude rétrospective a été entreprise chez 35 patients ambulatoires répondant aux diagnostics DSM III de troubles panique ou d’agoraphobie avec attaques de panique (AP), dans le but de mettre en évidence la chronologie d’apparition de différents symptômes d’anxiété chez ce type de patients. Dans plus de 90% des cas, la survenue d’AP précède ou inaugure l'apparition des symptômes permettant de porter les diagnostics mentionnés précédemment; comme cela est rapporté dans la littérature, ces AP paraissent survenir le plus souvent au décours d’une période de difficultés personnelles de natures diverses considérées comme «stressantes» par les patients con-cernés. D'autre part, chez 30% des patients répondant au diagnostic d’agoraphobie avec AP, on relève l'existence d’antécédents phobiques préexistant à l'apparition des premières crises d’angoisse-panique; l'existence de tels antécédents n'est relevée que chez 8% des patients répondant au diagnostic de troubles panique. L'hypothèse selon laquelle une prédisposition phobique favoriserait le développement de l'agoraphobie chez des patients présentant des AP répétées mériterait d’être confirmée par des enquêtes rétrospectives plus systématiques sur des échantillons cliniques plus larges.
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