Imazethapyr applied to the soil at 0, 35, 53, 70, 87, 105, and 140 g ai/ha followed by (fb) early-postemergence (EPOST) or late-postemergence (LPOST) applications at 140, 105, 87, 70, 53, 35, and 0 g ai/ha, respectively, was evaluated for weed control, crop tolerance, and grain yield in imidazolinone-tolerant rice. In drill- and water-seeded rice, imazethapyr effectively controlled barnyardgrass 91 to 97% with a soil fb EPOST or LPOST application except when applied at 105 fb 35 g/ha EPOST at 49 d after late-postemergence treatment. Rice yields were 5,920 and 3,920 kg/ ha in the drill-seeded study with a single application of imazethapyr at 140 g/ha EPOST in 2000 and 2001, respectively. These yields were greater than or equal to those from treatments with two imazethapyr applications.