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This chapter covers the basic principles, concepts, and tools governing the operation of the equipment and systems described in Chapter 3. The operation of those systems in off-design conditions, steady as well as unsteady (transient), are described using basic formulae and charts.
Detection of transients such as supernovae (SNe) and kilonovae (KNe) in early phase has recently become important for understanding the progenitor properties and multi-messenger astronomy. Predicting which galaxy has the higher probability of hosting the transient events would help detect the early phase of the events and get information on their progenitors. The SN and KN rates are known to be a function of star formation rate (SFR) and stellar mass of the host galaxy. The SFR of a galaxy can be estimated from ultraviolet (UV) luminosity. However, the UV magnitudes have been derived carefully only for a limited number of nearby galaxies. Here, we introduce GALEX galaxy catalog of all-sky UV brightness of low redshift galaxies. To do so, we derive the UV photometry of galaxies in the GLADE catalog using the GALEX AIS images, supplemented by GALEX NGS and MIS data. From the near-UV (NUV) and far-UV (FUV) magnitudes, we calculate the SFRs of the galaxies, which will further be useful for estimating the SN and KN rate. The results are compared with previous GALEX UV catalog of galaxies. There will be an updated catalog based on this catalog for calculating KN rate of the galaxies in the future work.
Acute kidney injury is a common complication following the Norwood operation. Most neonatal studies report acute kidney injury peaking within the first 48 hours after cardiac surgery. The aim of this study was to evaluate if persistent acute kidney injury (>48 postoperative hours) after the Norwood operation was associated with clinically relevant outcomes.
Methods:
Two-centre retrospective study among neonates undergoing the Norwood operation. Acute kidney injury was initially identified as developing within the first 48 hours after cardiac surgery and stratified into transient (≤48 hours) and persistent (>48 hours) using the neonatal modification of the Kidney Disease: Improving Global Outcomes serum creatinine criteria. Severe was defined as stage ≥2. Primary and secondary outcomes were mortality and duration of ventilation and hospital length of stay.
Results:
One hundred sixty-eight patients were included. Transient and persistent acute kidney injuries occurred in 24 and 17%, respectively. Cardiopulmonary bypass and aortic cross clamp duration, and incidence of cardiac arrest were greater among those with persistent kidney injury. Mortality was four times higher (41 versus 12%, p < 0.001) and mechanical ventilation duration 50 hours longer in persistent acute kidney injury patients (158 versus 107 hours; p < 0.001). In multivariable analysis, persistent acute kidney injury was not associated with mortality, duration of ventilation or length of stay. Severe persistent acute kidney injury was associated with a 59% increase in expected ventilation duration (aIRR:1.59, 95% CI:1.16, 2.18; p = 0.004).
Conclusions:
Future large studies are needed to determine if risk factors and outcomes change by delineating acute kidney injury into discrete timing phenotypes.
Socioeconomic difficulties affect the cognitive and emotional development of children. However, the focus of prior studies has largely been on poverty and material hardship. This study expands on the existing literature by examining the impact of familial transient financial difficulties during infancy on long-term cognitive and behavioral outcomes.
Methods
The National Longitudinal Surveys of Youth (79) were used to assess the association between a transient drop in family income by 50% or more (called transient income decline or TID) during the first 3 years of life and later-life Peabody Individual Achievement Math and Reading scores and behavior problem index (BPI) scores (N = 8272–17 348; median assessment age = 9 years). A subsample of matched siblings (N = 2049–4238) was examined to tease out maternal and intra-familial effects.
Results
Exposure to TID predicted increased total and externalizing BPI scores (std. coefficients of 0.10 and 0.09, respectively, p < 0.01) in the overall sample. Among matched siblings, exposure to TID predicted increased total, externalizing, and internalizing BPI scores (std. coefficients of 0.27, 0.25, and 0.23, respectively, p < 0.01).
Conclusion
Familial transient financial difficulties can have long-lasting behavioral effects for infants. The study identifies an early risk factor and at-risk children, thus providing insight into developing early intervention measures for infants to avoid long-term behavioral problems.
We show analogs of the classical arcsine theorem for the occupation time of a random walk in (−∞,0) in the case of a small positive drift. To study the asymptotic behavior of the total time spent in (−∞,0) we consider parametrized classes of random walks, where the convergence of the parameter to 0 implies the convergence of the drift to 0. We begin with shift families, generated by a centered random walk by adding to each step a shift constant a>0 and then letting a tend to 0. Then we study families of associated distributions. In all cases we arrive at the same limiting distribution, which is the distribution of the time spent below 0 of a standard Brownian motion with drift 1. For shift families this is explained by a functional limit theorem. Using fluctuation-theoretic formulae we derive the generating function of the occupation time in closed form, which provides an alternative approach. We also present a new form of the first arcsine law for the Brownian motion with drift.
Recent advancement of inorganic dissolvable electronics nucleates around a realization that single-crystal silicon nanomembrane undergoes hydrolysis in biologically relevant conditions. The silicon-based high-performance dissolvable electronic devices are initially conceived for biomedical implants that function for a programmed timeframe followed by a complete dissolution to eliminate the need for recollection. The technology developed for biomedicine also presents unique opportunities in security devices that physically destruct and in environmentally benign electronics that dissolve without a trace to reduce electronic wastes. The new class of devices with this emerging technology complements the existing efforts in organic biodegradable devices. Compatible with state-of-the-art fabrication facilities for commercial microelectronics, the technology has a huge potential for future commercialization. This mini review will first discuss the relevant materials for the inorganic dissolvable electronics and then present the demonstrated applications in functional devices, followed by a perspective for the future developments.
A heated triangular cylinder is suddenly cooled in a constant temperature bath. The transient heat conduction problem is transformed to the Helmholtz equation related to the vibration of membranes. Using the membrane analogy, exact analytic solutions for the transient heat conduction problem for three triangular cross sections are found.
This study applies the numerical inversion of Laplace transform methods to study the piezoelectric dynamic fracture problem, recalculating Chen and Karihaloo's [1] analysis on the transient response of a impermeable crack subjected to anti-plane mechanical and in-plane electric impacts. Three numerical methods were adopted for calculating the dynamic stress intensity factor: Durbin method, Zhao method 1, and Zhao method 2. The results obtained were more accurate than the results in Chen and Karihaloo's [1] study. Through the calculation, this study presents a better range of parameters for the above three methods, and compares the advantages and disadvantages of each method in detail.
In this paper, a newly developed second order temporally and spatially accurate finite difference scheme for biharmonic semi linear equations has been employed in simulating the time evolution of viscous flows past an impulsively started circular cylinder for Reynolds number (Re) up to 9,500. The robustness of the scheme and the effectiveness of the formulation can be gauged by the fact that it very accurately captures complex flow structures such as the von Kármán vortex street through streakline simulation and the α and β-phenomena in the range 3,000≤Re≤9,500 among others. The main focus here is the application of the technique which enables the use of the discretized version of a single semi linear biharmonic equation in order to efficiently simulate different fluid structures associated with flows around a bluff body. We compare our results, both qualitatively and quantitatively, with established numerical and more so with experimental results. Excellent comparison is obtained in all the cases.
A transient ischaemic attack (TIA) is a strong predictor of future stroke. Stroke is the most common cause of mortality in the United Kingdom. Management of risk factors can reduce the possibility of future strokes; however, these are often difficult to achieve optimally. Current evidence suggests that beliefs about causal attributions, severity and perceived risk of stroke may influence uptake of secondary prevention activities amongst this patient group.
Aim
To explore the illness beliefs of patients about TIAs and future risk of stroke, and to determine whether these beliefs determine secondary stroke prevention activities.
Method
A qualitative study comprising face-to-face, semi-structured interviews conducted in the homes of participants. Sampling was purposive and drawn from a single North London General Practice. A thematic framework analysis method was followed.
Findings
Eleven participants took part in the study (aged 46–86 years, three female participants and eight male participants). Time since diagnosis ranged from 2 to 25 years. There was a commonly held belief that TIAs are ‘short-lived events’ associated with full recovery, whereas strokes always lead to permanent ‘disability’. Only those who believed their TIAs to be ‘serious’ undertook activities to prevent further recurrence. Concordance with medication was the most popular prevention activity.
Conclusion
The traditional medical definition of TIA and stroke do not reflect the views of patients who have had TIAs. One's perception of the severity of the initial TIA event and the risk of future stroke episodes may influence the uptake of secondary stroke prevention activities. Post TIA stroke prevention interventions should include tailored discussions focussing on the importance of the acute event and its implications for long-term health and future stroke risk.
Five lagged cells were recognized by extracellular recording in the lateral geniculate nucleus of an awake, behaving macaque monkey. Previous reports of lagged cells were all in the anesthetized cat. Both parvocellular and magnocellular lagged cells were observed. Response timing was distributed continuously across the population, and both sustained and transient responses were seen in the magnocellular subpopulation. Cortex thus receives signals with a wide range of timing, which can mediate direction selectivity across multiple dimensions.
Rapid estimates of hospital capacity after an event that may cause a disaster can assist disaster-relief efforts. Due to the dynamics of hospitals, following such an event, it is necessary to accurately model the behavior of the system. A transient modeling approach using simulation and exponential functions is presented, along with its applications in an earthquake situation. The parameters of the exponential model are regressed using outputs from designed simulation experiments. The developed model is capable of representing transient, patient waiting times during a disaster. Most importantly, the modeling approach allows real-time capacity estimation of hospitals of various sizes and capabilities. Further, this research is an analysis of the effects of priority-based routing of patients within the hospital and the effects on patient waiting times determined using various patient mixes. The model guides the patients based on the severity of injuries and queues the patients requiring critical care depending on their remaining survivability time. The model also accounts the impact of prehospital transport time on patient waiting time.
La contribution de l'aérodynamique pour le développement durable et sécuritaire dans l'automobile est présentée et argumentée à partir de travaux de recherche destinés à contrôler les écoulements pour réduire la consommation et améliorer la stabilité dynamique. Les résultats révèlent la complexité des phénomènes physiques et des problématiques à résoudre pour pouvoir agir sur les mécanismes d'apparition, de développement, d'interaction et de stabilité des structures tridimensionnelles décollées instationnaires. Cette complexité confirme la nécessité de développer des coopérations afin d'améliorer la compréhension des phénomènes physiques et rechercher des solutions qui permettent de contrôler des écoulements décollés associés ou non à des configurations transitoires.
For a Markov chain in n = 2, drift vectors (conditional expected jumps) on the interior and the boundaries distinguish between recurrence and transience. The result of this paper is that the analogous proposition in the n = 3 case fails.
We investigate some properties of spherical means on the universal covering space of a compact Riemannian manifold. If the fundamental group is amenable then the greatest lower bounds of the spectrum of spherical Laplacians are equal to zero. If the fundamental group is nontransient so are geodesic random walks. We also give an isoperimetric inequality for spherical means.
Criteria are established for a discrete-time Markov process {Xn}n≧0 in Rd to have strictly positive, respectively zero, probability of escaping to infinity. These criteria are mainly in terms of the mean displacement vectors μ(y) = E{Xn+1|Xn = y} – y, and are essentially such that they force a deterministic process w.p.1 to move off to infinity, respectively to return to a compact set infinitely often. As an application we determine of most two-dimensional birth and death processes with rates linearly dependent on the population, whether they can escape to infinity or not.
A generalized queueing system with (N + 2) types of triplets (delay, service time, probability of joining the queue) and with uniformly bounded sojourn times is considered. An expression for the generating function of the Laplace-Stieltjes transforms of the waiting time distributions is derived analytically, in a case where some of the random variables defining the model have a rational Laplace-Stieltjes transform.
The standard Kl/Km/1 queueing system with uniformly bounded sojourn times is considered in particular.
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