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5 results

  • Inflammatory myofibroblastic tumour of the tonsil: case report and literature review

  • J C Magill, M S Ferguson, C R Butler, A Sandison, W E Grant
  • Journal:
    The Journal of Laryngology & Otology / Volume 124 / Issue 10 / October 2010
    Published online by Cambridge University Press:
    16 February 2010, pp. 1123-1125
    Print publication:
    October 2010
  • Objective:

    We present the first reported case in the English language literature of an inflammatory myofibroblastic tumour of the right tonsil in a young, pregnant woman, and we report a management strategy for this enigmatic entity.

    Case report:

    A 28-year-old, pregnant woman presented with a 10-day history of odynophagia despite a course of antibiotics. Examination revealed a grade II, erythematous right tonsil with ulceration on the upper pole. A biopsy was arranged, and initial evaluation was suggestive of spindle cell carcinoma. However, this diagnosis was reviewed after immunohistochemical staining confirmed an inflammatory myofibroblastic tumour. Subsequent complete excision was undertaken using CO2 laser.

    Conclusion:

    Clinically, inflammatory myofibroblastic tumour of the tonsil is known to be locally aggressive and can present in a manner not dissimilar to a high grade carcinoma of the tonsil. As a result, the recommended treatment is complete local excision with careful follow up.

  • Lichen sclerosis et atrophicus masquerading as tonsillar squamous cell carcinoma

  • O Ajayi, J C Stephens, S Karim, N Daly
  • Journal:
    The Journal of Laryngology & Otology / Volume 123 / Issue 2 / February 2009
    Published online by Cambridge University Press:
    23 December 2008, e10
    Print publication:
    February 2009
  • Objective:

    We report a case of a 70-year-old man of Asian origin with lichen sclerosus et atrophicus affecting the tonsil, which presented as a painful, enlarging, exophytic lesion mimicking squamous cell carcinoma.

    Method:

    We present a case report and a review of the world literature regarding lichen sclerosus et atrophicus.

    Results:

    Lichen sclerosus is a chronic, benign, inflammatory dermatosis of the skin and mucous membranes which mostly affects the female genitalia, presenting as white plaques with epidermal atrophy. The cause is unknown, although a number of aetiologies have been proposed. The prevalence is unknown. Women have been reported to be affected six to 10 times more than men, and the condition has no known racial preference.

    Conclusion:

    Our patient illustrates a rare case of the condition lichen sclerosus et atrophicus; to our knowledge, this case represents the first report of tonsillar involvement of the condition. The case presented a diagnostic challenge.

  • The blastic variant of mantle cell lymphoma arising in Waldeyer's tonsillar ring

  • Nadine S. Ives Aguilera, M. Uusafr, Bruce M. Wenig, Susan L. Abbondanzo
  • Journal:
    The Journal of Laryngology & Otology / Volume 112 / Issue 10 / October 1998
    Published online by Cambridge University Press:
    29 June 2007, pp. 991-994
    Print publication:
    October 1998

  • We present three cases of blastic mantle cell lymphoma with an unusual initial manifestation in Waldeyer's ring with methods for differentiating it from other blastic neoplasms of the head and neck. All cases presented with a feeling of fullness inthe area of the mass. Morphologically, the tumours were blastic with a high mitotic rate (three to nine per high power field). All were B-cell phenotype with coexpression of CD43. In all cases cyclin Dl and bcl-2 were positive and CD23 negative. Blastic mantle cell lymphoma occurring in Waldeyer's tonsillar ring may be mistaken for other high grade haematopoietic neoplasms. Immunohistochemistry and awareness of this type of lymphoma arehelpful in differentiating it from other neoplasms.