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Multiple reviews have examined the impact of nutritional interventions in patients with burn injuries; however, discrepancies among results cast doubt about their validity. We implemented this review to assess the impact of various nutritional interventions in adult patients with burn injuries. We conducted a thorough search of PubMed, Scopus and Web of Science databases until 1 August 2024, to identify relevant meta-analyses of intervention trials, examining the impact of nutritional interventions on burn patients. We adopted the random-effect models to determine the pooled effect sizes while employing the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) to examine evidence certainty. Thirty-three original intervention trials from eleven meta-analyses were entered in our review. Early enteral nutrition could substantially reduce overall mortality (relative risk (RR): 0·36, 95 % CI: 0·19, 0·68, GRADE = moderate certainty), hospital stay (mean difference (MD): −15·3, 95 % CI: −20·4, −10·2, GRADE = moderate certainty) and sepsis risk (RR: 0·23, 95 % CI: 0·11, 0·45, GRADE = moderate certainty). Glutamine showed a notable decrease in the length of hospital stay (MD: −6·23, 95 % CI: −9·53, −2·94, GRADE = low certainty). However, other nutritional interventions, including combined immunonutrition, branched-chain amino acids, fish oil, ornithine α-ketoglutarate and trace elements, did not significantly affect the assessed clinical outcomes. Early enteral nutrition might impose a beneficial effect on mortality, hospital stay length and incidence of sepsis with moderate evidence. Lower length of hospital stay was also seen in burn patients supplemented with glutamine, although the evidence was weak.
The chapter presents an overview of the procedural arrangements adopted at the international criminal jurisdictions, namely the UN ad hoc tribunals for the former Yugoslavia and Rwanda and the International Criminal Court (ICC), covering the main milestones from the initiation of the investigation to trial phase to appeals against the judgment and sentence and review. Before delving into the trajectories of an criminal case before international criminal courts and tribunals, the chapter highlights the origins of international criminal procedure in the common law (Anglo-American, or ‘adversarial’) and civil law (Continental, or ‘inquisitorial’) approaches, resulting in its legal nature as a hybrid scheme where the balance between the domestic influences varies by tribunal and over time due to reforms pursued by judge-legislators (ICTY and ICTR) or by states and, to a lesser extent, judges (ICC). The chapter reviews the role and functions of the main actors in international criminal proceedings, including repeat or professional players (judges, prosecutors, and defence) and other participants such as victims and witnesses and states and international organisations. It also highlights the normative importance of human rights to international criminal process and the imperative of complying with the principles of public, fair and expeditious proceedings.
This chapter discusses some of the existing beliefs about juror decision-making and the jury process at three distinct phases of a trial: before the trial, during the trial, and at the trial’s conclusion. Before the trial, there are beliefs surrounding the jury process, including jury duty, jury size, and jury selection (i.e. voir dire). During the trial, there are common beliefs surrounding courtroom factors that influence jury decision-making, including attitudes, beliefs, and expectations regarding attorneys, expert witnesses, confession evidence, and emotion-evoking evidence. Finally, at the end of trial, there is the existing belief that juries make extreme and unpredictable decisions in civil and criminal court. This chapter uses current research and empirical evidence within law and behavioral sciences to examine these myths, showing support for some of these beliefs, while also showing that others are simply myths about jury decision-making. Finally, the chapter discusses future research to address such myths.
This conclusion summarises how realistic trials and realistic systematic reviews offer a method by which evaluation and evidence synthesis can become more useful by becoming more scientific and moving beyond being a form of sophisticated descriptive monitoring of ‘what works’. Evaluation can become more scientific both by continuing to use the most scientifically rigorous methods, as well as by being focused on the testing and refining of scientific theory. Critical realism and realist evaluation approaches offer a useful framework for constructing such theory because they offer the most plausible account of how causality operates in the complex social world. We hope that, by making these arguments, we have persuaded readers that trials and systematic reviews need to be reoriented and reformed rather than thrown away altogether. The incorporation of realist enquiry methods into randomised trials and systematic reviews offers us the best hope of evaluation and evidence synthesis that generate evidence which is both more scientific and more useful.
The trial of Alice Kyteler in Kilkenny, Ireland, in 1324 took place as the result of charges made against this business woman by members of her own family. Richard Ledrede, bishop of Ossory, was keen to obtain her condemnation for demonic association, on the charges listed in this excerpt from the account of her trial which include sacrifices and the boiling of disgusting potions.
Oral witness is also the basis for the account of what Margery Baxter, charged with heresy at Norwich in 1428, has said and done. Her friends and neighbours are called to witness against her, and through their words we learn not only of the shocking things she has said which confirm her contempt for the Church, but details of the women’s lives.
The unprecedented COVID-19 pandemic has caused restrictive measures to be established in many sectors including the legal and judicial sector; an example is the use of electronic litigation systems and video-conferencing facilities for trials. With the implementation of changes in the legal and judicial sector to adapt to restrictions arising from the pandemic, there is the question of whether the current rules governing civil-court proceedings are designed to accommodate these changes. This article seeks to explore the measures taken by courts in response to the pandemic with a focus on Asia, notably Singapore. The article will outline the legal basis for the use of live video links for the purpose of witness evidence-taking under Singapore law and the possible implications will be reviewed taking Singapore’s civil proceedings as an example in comparison with other jurisdictions.
Negative symptoms are core symptoms of schizophrenia which are common throughout the course of the illness. We outline their functional impact, before reviewing the latest research and guidelines on their assessment and treatment. Finally, we discuss conceptual issues related to measurement of negative symptoms and approaches to address these.
Judicial law-making has frequently been likened to arts and crafts of various sorts, from minting coins to writing novels. While considering these analogies and how they demonstrate the reality of the law’s fabricating processes, the deeper aim of this chapter is to challenge the assumption that facts and truths established in law courts are ‘found’ and ‘discovered’. It is only by acknowledging that legal facts and legal truths are made by judicial crafts that we will come to appreciate the merits of those crafts and to discern the attributes of truth-making in courts that set the standard by which to judge the quality of truth claims in other contexts.
In jurisdictions with two or more tiers of criminal courts, some defendants can choose the type of trial court to be tried in. This may involve a trade-off between the probability of acquittal/conviction and the estimated severity of sentence if convicted. For instance, in England and Wales, the lower courts have a higher conviction rate but limited sentencing powers, whereas the higher courts have a higher acquittal rate but greater sentencing powers. We examined 255 offenders’ choice of trial court type using a hypothetical scenario where innocence and guilt was manipulated. Participants’ choices were better predicted by a lexicographic than utility maximization model. A greater proportion of “guilty” participants chose the lower court compared to their “innocent” counterparts, and estimated sentence length was more important to the former than latter group. The present findings provide further support for heuristic decision-making in the criminal justice domain, and have implications for legal policy-making.
An emotive, haunting story of a community torn apart, the Essex witch accusations and trial of 1581-2 are, taken together, one of the pivotal instances of that malign and destructive wave of misogynistic persecution which periodically broke over early modern England. Yet, for all their importance in the overall study of witchcraft, the so-called witches of St Osyth have largely been overlooked by scholars. Marion Gibson now sets right that neglect. Using fresh archival sources – and investigating not just the village itself, but also its neighbouring Elizabethan hamlets and habitations – the author offers revelatory new insights into the sixteen women and one man accused of sorcery while asking wider, provocative questions about the way history is recollected and interpreted. Combining landscape detective work, a reconstruction of lost spaces and authoritative readings of newly identified key documents, Gibson skilfully unlocks the poignant personal histories of those denied the chance to speak for themselves.
This chapter explores the trial of the St Osyth witches and the witches from surrounding communities, and follows them to their judgement and - in some cases - their deaths. It examines the creation of the news pamphlet that recounted the story of the witch trial, and suggests an author for that famous account, showing how it shaped the story of the St Osyth witches that has been handed down to modern readers.
An emotive, haunting story of a community torn apart, the Essex witch accusations and trial of 1581-2 are, taken together, one of the pivotal instances of that malign and destructive wave of misogynistic persecution which periodically broke over early modern England. Yet, for all their importance in the overall study of witchcraft, the so-called witches of St Osyth have largely been overlooked by scholars. Marion Gibson now sets right that neglect. Using fresh archival sources – and investigating not just the village itself, but also its neighbouring Elizabethan hamlets and habitations – the author offers revelatory new insights into the sixteen women and one man accused of sorcery while asking wider, provocative questions about the way history is recollected and interpreted. Combining landscape detective work, a reconstruction of lost spaces and authoritative readings of crucial documents, Gibson skilfully unlocks the poignant personal histories of those denied the chance to speak for themselves.
This paper examines the position taken and the discourse on the right of silence in Singapore. By position, I mean what the law is and how it got there. By discourse, I mean how officials talk when they go about defending legislative amendments or praising the current law. Does the experience in Singapore reveal a distinctly Asian perspective to the right of silence? The study of Singapore will be used as a springboard for theoretical reflections on the right in general. I hope to illustrate or instantiate this general point: while evidential reasoning is primarily theoretical; it is legally regulated by rules that are often shaped by practical – including political and ethical – considerations.
The rioting and looting after Henry Hunt’s great reform meeting on Spa Fields on 3 December 1816 marked a turning point in Thistlewood’s career. Its failure led to his attempt to flee to America, to his capture, and in June 1817 to the aborted treason trial of Watson, Preston, Thistlewood, and Hooper. This collapsed once it was shown to be based on the evidence of the spy John Castle.Henceforth Thistlewood was a marked man on the extremist edges of London radicalism.
Chapter 2 examines the largely overlooked writings of nineteenth-century clinicians, scientists, lawyers, and jurists who actually called for a third sex to be added alongside the ranks of “male” and “female” because, quite plainly, there were individuals for whom no “true sex” could be identified. The inflexibility of the Napoleonic Code, which required that all infants be sexed as either male or female at birth, was challenged by doctors and legal forensics experts who believed either that the Code was out of step with scientific progress, or that it did not do enough to protect citizens from “hermaphrodites.” In sensationalized court cases that riveted domestic and international audiences – both scientific and lay – doctors and jurists struggled to reconcile cases of “doubtful sex” with scientific evidence, social welfare, and the Code itself. Intersex people came into conflict with the law from the moment of their birth. Jurisconsults enthusiastically contradicted one another about the veracity of sex determinations, while influential men labored to revise laws regarding birth certificates, marriage, divorce, and inheritance. Ultimately, the only party remaining silent on “hermaphrodism” was the Code itself, ensuring that a legal blind spot only increased the visibility of those it tried not to see.
In the eighteenth century, the Massachusetts House criminalized speech, and the general sessions courts prosecuted it, for being impolite as well as ungodly. Politeness became a core element of social order and elite white masculine identity. This study identified more than 1,600 criminal speech prosecutions in the records of justices and courts. These include any document that specified verbal threats or abuse; profane cursing or swearing; verbal noise; lying; false reports; defamatory speech; or perjury. Criminal procedure was simple and discretionary, and required widespread community participation in order to effectively prosecute impolite speech. Such prosecutions helped to define elite identity and status around matrices of sensibility, civility, and credibility. Sensibility was a moral and genteel quality not manifested by those prosecuted for noisy or abusive speech. Civility connoted pleasurable sociability that was undermined by contempt, cursing, and defamation. Credibility was the gentlemanly reputation for truthfulness, destroyed by lying, perjury, false news, and mumpers (pretended gentlemen). The Revolution replaced this regime with one based on respectability.
This chapter concerns civil litigation trials. Trials are actually one of the least common means of civil dispute resolution. In addition to the significant portion of civil disputes which are resolved without any recourse to litigation, the overwhelming majority of civil litigation cases which are commenced never make it to trial. Most cases for which litigation proceedings commence are resolved by ADR1 or summary disposition.2 This is because trials are one of the most expensive aspects of litigation, so it is natural for civil disputants and courts to avoid trials wherever possible in the interests of efficiency. However, a full trial is the only way civil disputants are able to put their entire case, with all the evidence, before an independent decision-maker applying full due process and fully exercising their right to be heard. Accordingly, the decision by parties to pursue the trial process is an example of the key civil dispute resolution theme of balancing efficiency against due process.
Consent is the issue at the heart of Chapter 3. Peine forte et dure was necessary simply because the English court system required a defendant’s consent before he might be submitted to trial by jury. Without his consent, justices could not proceed to trial. This chapter asks why did English justices see consent as vital, especially when other Europeans did not? It explains that consent was a traditional part of English legal culture, signaled by a defendant’s choice of proofs (compurgation, ordeals, battle). In choosing a method of proof, an accused felon recognized the court’s authority in the matter, and consented to abide by its decision. With the transition from proofs to trial (by jury) that began under Henry II and coalesced with Lateran IV’s abandonment of the ordeal, a defendant’s rights were whittled away. These changes took place against the backdrop of the twelfth-century legal revolution that championed a defendant’s natural rights to legal protection. Thus, while the English may have protested the loss of choice through silence, justices needed a solution that respected both English heritage and a defendant’s rights. That solution was peine forte et dure.
To assess the effect of individual compared to clinic-level feedback on guideline-concordant care for 3 acute respiratory tract infections (ARTIs) among family medicine clinicians caring for pediatric patients.
Design:
Cluster randomized controlled trial with a 22-month baseline, 26-month intervention period, and 12-month postintervention period.
Setting and participants:
In total, 26 family medicine practices (39 clinics) caring for pediatric patients in Virginia, North Carolina, and South Carolina were selected based upon performance on guideline-concordance for 3 ARTIs, stratified by practice size. These were randomly allocated to a control group (17 clinics in 13 practices) or to an intervention group (22 clinics in 13 practices).
Interventions:
All clinicians received an education session and baseline then monthly clinic-level rates for guideline-concordant antibiotic prescribing for ARTIs: upper respiratory tract infection (URI), acute bacterial sinusitis (ABS), and acute otitis media (AOM). For the intervention group only, individual clinician performance was provided.
Results:
Both intervention and control groups demonstrated improvement from baseline, but the intervention group had significantly greater improvement compared with the control group: URI (odds ratio [OR], 1.62; 95% confidence interval [CI], 1.37–1.92; P < 0.01); ABS (OR, 1.45; 95% CI, 1.11–1.88; P < 0.01); and AOM (OR, 1.59; 95% CI, 1.24–2.03; P < 0.01). The intervention group also showed significantly greater reduction in broad-spectrum antibiotic prescribing percentage (BSAP%): odds ratio 0.80, 95% CI 0.74-0.87, P < 0.01. During the postintervention year, gains were maintained in the intervention group for each ARTI and for URI and AOM in the control group.
Conclusions:
Monthly individual peer feedback is superior to clinic-level only feedback in family medicine clinics for 3 pediatric ARTIs and for BSAP% reduction.
Trial registration:
ClinicalTrials.gov identifier: NCT04588376, Improving Antibiotic Prescribing for Pediatric Respiratory Infection by Family Physicians with Peer Comparison.