Field experiments were conducted in 1991 and 1992 to evaluate corn tolerance to nicosulfuron following in-furrow or surface-band applications of seven soil-applied insecticides. The organophosphate insecticides evaluated included terbufos (15G and 20CR formulations), phorate, chlorpyrifos, fonofos, and DPX-43898, as well as the synthetic pyrethroid tefluthrin. Potential for a nicosulfuron/ insecticide interaction to injure corn was ranked as follows: terbufos 15G = phorate > terbufos 20CR > fonofos. Chlorpyrifos, DPX-43898, or tefluthrin followed by nicosulfuron caused no significant corn injury. Corn injury and yield reduction were greater in corn treated in-furrow compared with surface-band. Soil moisture at nicosulfuron application was more influential in causing corn injury and loss of yield than growth stage of corn at nicosulfuron application.