Introduction: Practice guidelines discourage routine imaging for low back pain and recommend selective use when serious underlying conditions are suspected. Evidence about prevalence of serious pathologies and accuracy of red flags for decision-making is limited. We describe rates of serious low back pathology, assess the accuracy of three red flags and model the utility of combining administratively available red flags to reduce imaging. Methods: A seven-year retrospective study of patients presenting with low back pain to four emergency departments in Nova Scotia, Canada. Patient characteristics were available from administrative data. We test sensitivity, specificity, positive and negative predictive values, and likelihood ratios of individual and combinations of red flags. We use decision curve analyses to assess the clinical utility of three red flags to inform imaging. Results: We included data from 38,714 patients presenting with low back pain. Serious low back pathology was diagnosed in 1196(3.09%): 847 (2.19%) were vertebral fractures, 184 (0.48%) unstable fracture, 262 (0.68%) cancer, 57 (0.15%) cauda equina syndrome, and 30 (0.08%) spinal infection. Value of combining three red flags (age>65, female sex, and trauma) was found: positive likelihood ratios of 4.36 and 9.74 for vertebral fracture and unstable fracture, respectively. Imaging for low back pain could be reduced by 28 per 100 patients using a model that incorporates sex, age >65, and trauma. Conclusion: Serious low back pathology is extremely rare in patients presenting with low back pain. Combinations of red flags readily available in emergency departments have the potential to reduce unnecessary imaging tests.

Introduction: Carotid artery stenosis (CAS) is a common cause of stroke. Patients with severe, symptomatic CAS can have their subsequent stroke risk reduced by carotid endarterectomy or stenting when completed soon after a TIA or non-disabling stroke. Patients presenting to a peripheral ED with TIA/stroke, may require transfer to another hospital for imaging to rule-out CAS. The purpose of this study was to determine the test characteristics of carotid artery POCUS in detecting greater than 50% stenosis in patients presenting with TIA/stroke. Methods: We conducted a prospective cohort study on a convenience sample of adult patients presenting to a tertiary care academic ED with TIA/stroke between June and October 2017. Carotid POCUS was performed by a trained medical student or a trained emergency physician. Our outcome measure, CAS >50% was determined by the final radiology report of CTA imaging by a trained radiologist, blinded to our study. A blinded POCUS expert reviewed the carotid POCUS scans. We calculated the sensitivity and specificity for CAS >50% using carotid POCUS versus the gold standard of CTA. Results: We enrolled 75 patients of which 5 did not meet inclusion criteria. The mean age was 70.4 years, 57% were male. 16% were diagnosed with greater than 50% CAS. 47% were stroke codes and 37% were admitted to hospital. Carotid POCUS had a sensitivity and specificity of 72% (46%-99%) and 88% (80%-96%) respectively. There were three false negatives of which two were exactly 50% ICA stenosis on CTA and the other was 100% occlusion of the distal ICA. Kappa coefficient for inter-rater reliability between standard and expert interpretation was 0.68 for moderate agreement. The scan took a mean time of 6.2 minutes to complete. Conclusion: Carotid POCUS has moderate correlation with CTA for detection of CAS greater than 50%. Carotid POCUS identified all the critical 70-99% stenosis lesions that would need urgent surgery. Further research is needed to confirm these findings.

Introduction: Our objective is to investigate predictors of adverse patient reported outcomes during the 10 days after an index emergency department (ED) encounter for ureteral colic. Methods: This prospective two-city patient experience survey enrolled ED patients with confirmed 2-10 mm ureteric stones. Researchers telephoned consenting patients 10 days post-ED visit and assessed quality of life (QoL) using survey items from the VR-12 Health Outcome Survey. We used five survey items and three other variables to derive a composite measure of patient adverse experience (AE). The association between patient characteristics, symptoms and perceptions of care with outcome was determined using multiple logistic regression. Results: Of 224 patients studied (68% male, mean age 52 years) 154 (68.8%) indicated that one or more of the following AEs occurred during their 10day followup interval: 103 (46%) reported that the impact of pain on their life was >4/10; 87 (39%) described poor or fair health status; 83 (37%) required >7days for return of normal function; 66 (27.7%) had >2 severe pain episodes per day; 62 (27.7%) required ED revisit or hospitalization; 47 (21%) found usual activities were limited most or all the time; 45 (20%) required >2 opioid doses/day; and 24 (10.7%) lost >7 work days. A composite measure derived from 3 survey items (days to normal, pain impact, health status) captured 92% of patients with adverse experiences. On multivariable logistic regression modeling, the strongest predictors of adverse (composite) outcome were male sex (adjusted OR=0.44; CI, 0.22-0.85), (excellent) quality of physician answers (OR=0.40; CI,0.2-0.77), proximal or mid-ureteric stone (OR=1.9; CI, 1.1-3.5), arrival pain severity (OR=1.18 per unit increase; CI,1.01-1.4), and perceived physician skill (OR=0.81; CI, 0.65-1.0). Patient age, stone size, pain duration, nausea, discharge pain and perceived ED care quality were not independent predictors of 10-day adverse patient experience in multivariate models. Conclusion: Patient sex, quality of physician communication, patient sex, arrival pain severity, and proximal stone location are highly associated with 10-day patient reported AE.

Introduction: Pulse check by manual palpation (MP) is an unreliable skill even in the hands of healthcare professionals. In the context of cardiac arrest, this may translate into inappropriate chest compressions when a pulse is present, or conversely omitting chest compressions when one is absent. To date, no study has assessed the utility of B-mode ultrasound (US) for the detection of a carotid pulse. The primary objective of this study is to assess the time required to detect a carotid pulse in live subjects using US compared to the standard MP method. Methods: This is a prospective randomized controlled cross-over non-inferiority trial. Health care professionals from various backgrounds were invited to participate. They attended a 15 minute focused US workshop on identification of the carotid pulse. Following a washout period, they were randomized to detect a pulse in live subjects either by MP first or by US first. Both pulse check methods were timed for each participant on 2 different subjects. The primary outcome measure was time to carotid pulse detection in seconds. Secondary outcome measures included comfort levels of carotid pulse detection measured on a 100mm visual analog scale (VAS), and rates of prolonged pulse checks (greater than 5 or 10 seconds) for each technique. Mean pulse detection times were compared using Students t-test. The study was powered to determine whether US was not slower than MP by greater than 2 seconds. Results: A total of 93 participants completed the study. Time to detect pulse was 4.2 (SD=3.4) seconds by US compared with 4.7 (SD=6.5) seconds by MP (P=0.43). Seventeen (18%) participants took >5 seconds to identify the carotid pulse using US compared to 19 (20%) by MP (P=0.74). Eight (9%) candidates took >10 seconds to identify the pulse using US compared to 9 (10%) by MP (P=0.81). Prior to training, participants had a higher comfort level using MP than US pulse checks (67 vs 26 mm, P<0.001). Following the study, participants reported higher comfort levels using US than MP (88 vs 78 mm, P<0.001). Conclusion: Carotid pulse detection in live subjects was not slower using US as compared to MP in this study. A brief teaching session was sufficient to improve confidence of carotid pulse identification even in those with little to no previous US training. The preliminary results from this study provide the groundwork for larger studies to evaluate this pulse check method for patients in actual cardiac arrest.

Introduction: Point-of-Care Ultrasound (POCUS) is rapidly being integrated into Pediatric Emergency Medicine (PEM), and image interpretation is an important component of this skill. Currently, PEM physicians often rely on case-by-case exposure and feedback by a POCUS expert physician to learn this skill; however, this may not be efficient, reliable or feasible. Thus, there is a pressing need to develop effective POCUS image interpretation learning and assessment tools. We developed an on-line learning platform that allowed for the deliberate practice of images in four POCUS applications [soft tissue, lung, cardiac and Focused Assessment Sonography for Trauma (FAST)], and determined the quantity of participant skill acquisition by deriving performance metrics and learning curves. Methods: This was a prospective cross-sectional study administered via an on-line learning and measurement platform. Images were acquired from a pediatric emergency department and each POCUS application contained 100 still/video images. Final diagnosis of each image was determined via the consensus of three PEM POCUS experts. PEM fellow and attending study participants were recruited from the USA and Canada and were required to complete the cases of at least one application. We aimed to enroll 200 participants who had to complete a minimum of 100 cases which, based on prior work, would provide sufficient raters for item analyses and comparisons between PEM attendings and fellows. To derive reference standard performance metrics and to validate image interpretations, a unique set of five PEM POCUS experts completed each application. Results: We enrolled 225 PEM physicians, 74 fellows and 151 attendings. For all applications, the Cohens d effect size was large at 0.87, and there was no difference between PEM attendings and fellows with respect to summary performance metrics (accuracy, p= 0.29; sensitivity, p=0.13; specificity, p=0.92). Final accuracy soft tissue, lung, cardiac, and FAST for all participants was 86.4%, 89.6%, 81.6%, 88.0%, respectively, and the corresponding accuracy of PEM POCUS experts for each application was 96.0%, 96.0%, 90.0%, and 93.0%. Learning curves show maximal learning gains (inflection point) up until 65 cases for soft tissue, 70 for FAST, 75 for lung, and 85 for cardiac. Conclusion: Deliberate practice of POCUS image interpretation was effective for ensuring broad domain coverage and predictable skill improvement. Specifically, there was a large learning effect after 100 case interpretations, and 65-85 case interpretations were needed to reach an accuracy threshold of approximately 85%.

Introduction: In high-income countries, vomiting often impedes oral rehydration therapy, leading to intravenous rehydration fluid administration to children with acute gastroenteritis. Ondansetron administration reduces vomiting and intravenous fluid administration in this population. We evaluated whether ondansetron is similarly effective when employed in Pakistan. Methods: In this 2-hospital, double-blind, placebo-controlled, emergency department-based, randomized trial, we recruited children aged 0·5 to 5·0 years, without dehydration, who had diarrhea and 1 episode of vomiting within 4 hours of arrival. Patients were randomly assigned (1:1), via an internet-based randomization service, using a stratified, variable block randomization scheme, to receive a single dose of oral ondansetron or placebo. The primary endpoint was intravenous rehydration (administration of 20 ml/kg over 4 hours of an isotonic fluid) within 72 hours of randomization. All randomized children were analysed. Results: From July 3, 2014, to January 12, 2017, 626 children were randomized. Intravenous rehydration was provided to 10.8% (34/314) and 10.3% (27/312) of children administered placebo and ondansetron, respectively (OR: 0.946; 95% CI: 0.564, 1.587; P=0.834). A regression model fitted with treatment group and adjusted for antiemetic administration and vomiting frequency in the preceding 24 hours, yielded similar results; OR=0.952; 95% CI: 0.570, 1.589; P=0.850. There was no evidence of interaction between treatment group and age (P=0.974), 3 diarrheal stools in the preceding 24 hours (P=0.983) or 3 vomits in the preceding 24 hours (P=0.554). During the 4-hour study observation period, 24.0% (75/314) and 19.6% (61/312) of children in the placebo and ondansetron groups vomited, respectively; OR: 0.774; 95%CI: 0.528, 1.133; P=0.187. Conclusion: Ondansetron administration did not significantly reduce intravenous rehydration use, suggesting that in children without dehydration, ondansetron administration does not significantly alter the disease course and should not be administered to this group of children.

Introduction: Correctly identifying pathology in pre-pubertal females is a high-stakes physical examination skill. Currently, learning this skill relies heavily on case-by-case exposure, which is variable, limited and often results in suboptimal skill. Thus, there is a need to develop and evaluate learning platforms that simulate the presentation and diagnosis of this important clinical task. We developed an on-line learning and assessment platform that allowed the deliberate practice of 158 pre-pubertal female genital image interpretations . We examined the quantity of skill acquisition by deriving performance metrics and learning curves. Methods: This was a prospective cross-sectional study administered via an on-line learning and assessment platform. Colposcopic images were acquired from a child abuse clinic. Two child abuse experts interpreted images to determine case solutions and 40% of cases had medical or traumatic pathology. Further, to validate image interpretations, a unique set of five child abuse and pediatric gynaecology experts reviewed the cases. Study participants were recruited from the USA and Canada and were required to complete all 158 cases. For each image, learners designated cases as normal or abnormal and if abnormal indicated the abnormal area on the image. The primary outcome was the change in accuracy, sensitivity and specificity. Results: We enrolled 107 participants, 26 medical students, 31 pediatric residents, 24 pediatric emergency fellows, and 26 pediatric emergency attendings. For all participants, the change in accuracy was +9.6% for accuracy (<0.001), +1.4% for sensitivity (p=0.6) and +15.7% (p<0.001) for specificity. The final score for accuracy, sensitivity and specificity was 79.5%, 66.1%, and 87.8%, respectively. There was no difference between learner types with respect to summary performance metrics (accuracy, p=0.15; sensitivity, p=0.44; specificity, p=0.54). Learning curves show maximal learning gains (inflection point) up until 100 cases. Conclusion: Deliberate practice of pre-pubertal female image interpretation was effective for ensuring predictable skill improvement for normal cases but was less effective for abnormal cases. Future research could examine how to refine the education tool to better serve diagnostic skill of abnormal cases.

Introduction: The diagnosis of Salter-Harris Type 1 fractures in the Emergency Department (ED) is primarily clinical, as radiographs are usually unrevealing. We hypothesize that bilateral asymmetry of the growth plate, detected using bedside ultrasound (US), could improve the accuracy of this diagnosis in the ED. This study seeks to determine growth plate size according to age, and to establish normal variation in bilateral symmetry of growth plate cartilage, for the ulna, radius, tibia, and fibula, using bedside US in normal healthy children. Methods: This prospective observational study was conducted in a convenience sample of children ages 0-17 during planned visits to an elementary school, high school, and an outpatient pediatric clinic. A sample size of 177 was determined with a linear regression model using previously published data on the subject. The study was approved by the hospital and universitys ethics board. After a medical questionnaire with a research nurse, the participants underwent ultrasound evaluation of bilateral ulnae, radii, fibulae, and tibiae, to obtain still images of the physes from two orthogonal views. The evaluations were performed by 3 medical residents, 1 medical student, and by the supervising emergency physician. All ultrasonographers were EDE1 certified and specifically trained for growth plate imagery. The still images were evaluated ulteriorly and measurements taken of the physeal cartilage. Ten percent of the patients had their images re-evaluated by the supervising physician to determine inter-rater reliability. Results: A total of 227 patients were recruited. The median age was 8 years old with an interquartile range of (3;14). Mean growth plate size by age was determined, confirming decreasing growth plate size with advancing age for all articulations. The percentage of absolute difference between right and left, for all growth plates together, was a mean of 17% with a 95% CI of 16-19%. The overall inter-rater reliability was excellent at 0.84. Conclusion: This study establishes a reproducible technique of measuring growth plates with ultrasound. We suspect that increased asymmetry at the growth plate, beyond this established normal variation, may signify a physis widening or hematoma consistent with a Salter-Harris Type 1 fracture; this will be evaluated in a second study.

Introduction: The opioid crisis in North America has led to more rigorous prescribing guidelines in various practice settings. Recent studies suggest that the Emergency Department is an environment with increased opioid prescribing, leading to increased rates of long-term use and dependence in opioid naive patients. Prior reviews of international opioid prescribing guidelines have demonstrated overall congruence of practice recommendations, although these are focused on primary care prescribers. The goal of this study was to review international opioid prescribing guidelines for recommendations relevant to emergency department practitioners. Methods: The search strategies of prior congruence studies were reproduced, updated and supplemented by electronic database and specialty organization searches. Only the most recent iteration of a published guideline was included, unless it was a limited update of a prior more comprehensive guideline, in which case both were assessed. Prescribing guidelines were included if they represented national practice statements, national or international specialty organizations generating guidelines. Sub-national or regional guidelines were excluded due to local practice bias tendency. Included guidelines were independently reviewed for evidence evaluation and recommendation formulation frameworks, relevance of recommendations for emergency medicine (EM) practice (and supporting levels of evidence), inclusion of EM authors (and corresponding conflict of interest statements), and involvement of EM-relevant stakeholders in reviewing guideline publications. Results: Sixteen international and specialty organization guidelines were included in the review. Evidence evaluation and recommendation formulation frameworks were incompletely reported (12/16), and used a multitude of evaluation processes when reported. Two guidelines included EM-relevant recommendations based on weak evidence. Three guidelines included EM authors, one of which reported a conflict of interest. None of the included guidelines were reviewed by EM-relevant stakeholder organizations prior to publication. Conclusion: International and specialty organization opioid prescribing guidelines virtually ignore relevant recommendations for EM practice, and any supporting evidence is weak. Emergency practitioners are nearly absent from authorship groups, and are excluded from external review of draft documents prior to final publication. This study reinforces the urgent need for EM organizations to create guidance documents around opioid prescribing for their own practitioners, and involving appropriate EM stakeholders.

Introduction: The Canadian Institute for Health Information reports the rate of child and youth emergency department (ED) visits for mental health complaints increased by 50% between 2007 and 2015. Improving care for these patients is a major priority of Alberta Health Services (AHS). As part of a multi-phased approach to improving care, the Emergency and the Addiction and Mental Health Strategic Clinical Networks (SCNs) surveyed youth who had presented to an ED for mental health or substance use concerns and their families/caregivers. Methods: The online survey contained closed- and open-ended questions on reasons for ED visits, expectations about and experiences during their visits, and areas for improvement. An ethics approved survey was conducted for 4 weeks. Participants were recruited across the province using an extensive array of social media platforms. For each survey, we randomly selected a sample of open-ended responses to thematically analyze to the point of informational redundancy. Results: The Youth survey received 992 responses and the Family survey received 553. A small number of overarching themes emerged. For both surveys, the major themes were 1) Wait times and access: participants were disappointed with lengthy wait times and services in the community. Youth said this made them question their decision to seek help and left them feeling hopeless. 2) Care provider training: participants were unhappy with the quality of care provided (e.g., lack of compassion, minimizing symptoms). They felt better training would improve care and attitudes towards mental health patients. 3) Environment: participants were uncomfortable with the lack of privacy for discussing sensitive topics; youth also requested items such as pens/paper and phone chargers to make the stay more comfortable and provide distractions. An additional theme emerged in the Youth survey regarding family involvement; participants wanted to decide how much/what information is shared with their families. Youth noted they were less likely to be honest with family present. Communication and navigation were mentioned frequently in the Family survey; participants noted the complexity of the mental health care system and felt frustrated by the lack of information to help them access additional resources. Conclusion: There are a number of areas in need of improvement to provide high-quality, patient-centred care to youth with mental health or substance use concerns that present to the Emergency Department. Phase II of this project will involve a review of the themes and determine priorities and strategies to address the themes that could be implemented into the workflow.

Introduction: Inadequate pain management in children is ubiquitous in the emergency department (ED). As the current national opioid crisis has highlighted, physicians are caught between balancing pain management and the risk of long term opioid dependence. This study aimed to describe pediatric emergency physicians (PEPs) willingness to prescribe opioids to children in the ED and at discharge. Methods: A unique survey tool was created using published methodology guidelines. Information regarding practices, knowledge, attitudes, perceived barriers, facilitators and demographics were collected. The survey was distributed to all physician members of Pediatric Emergency Research Canada (PERC), using a modified Dillmans Tailored Design method, from October to December 2017. Results: The response rate was 49.7% (124/242); 53% (57/107) were female, mean age was 43.6 years (+/− 8.7), and 58% (72/124) had pediatric emergency subspecialty training. The most common first line ED pain medication was ibuprofen for mild, moderate and severe musculoskeletal injury (MSK-I)-related pain (94.4% (117/124), 89.5% (111/124), and 62.9% (78/124), respectively). For moderate and severe MSK-I, intranasal fentanyl was the most common opioid for first (35.5% (44/124) and 61.3% (76/124), respectively) and second line pain management (41.1% (51/124) and 20.2% (25/124), respectively). 74.8% (89/119) of PEPs reported that an opioid protocol would be helpful, specifically for morphine, fentanyl, and hydromorphone. Using a 0-100 scale, physicians minimally worried about physical dependence (13.3 +/−19.3), addiction (16.6 +/−19.8), and diversion of opioids (32.8+/−26.4) when prescribing short-term opioids to children. They reported that the current opioid crisis minimally influenced their willingness to prescribe opioids (30.0 +/−26.2). Physicians reported rarely (36%; 45/125) or never (28%; 35/125) completing a screening risk assessment prior to prescribing opioids. Conclusion: Ibuprofen remains the most common medication recommended for MSK-I pain in the ED and at discharge. Intranasal fentanyl was the top opioid for all pain intensities. PEPs are minimally concerned regarding dependence, addiction, and the current opioid crisis when prescribing short-term opioids to children. There is an urgent need for robust evidence regarding the dependence and addiction risk for children receiving short term opioids in order to create knowledge translation tools for ED physicians. Opioid specific protocols for both in the ED and at discharge would likely improve physician comfort in responsible and adequate pain management for children.

Introduction: Accurate identification of children with a concussion by emergency department (ED) physicians is important to initiate appropriate anticipatory guidance and management. In children meeting international criteria for concussion, we aimed to determine the proportion who were provided this diagnosis by the ED physician and which variables were associated with a physician-diagnosed concussion. We also compared persistent symptoms in concussion cases versus those with alternative diagnoses. Methods: This was a planned secondary analysis of a prospective, multicenter cohort study. Participants were children aged 5 through 17 years and met Zurich/Berlin International Consensus Statement criteria for concussion. The primary outcome was the proportion of study participants who were assigned a diagnosis of concussion by the treating ED physician. Based on available evidence, between 50% and 90% of children meeting international concussion criteria are also diagnosed by an ED physician as having a concussion. Assuming a worst case scenario that 50% of physicians would diagnose concussion, our anticipated study sample size of 2946 would be accompanied by a +2% margin of error at the 95% confidence level for the primary outcome. Results: Among the 2946 eligible children, 2340 [79.4% (95% CI 78.0, 80.8)] were diagnosed with a concussion by an ED physician. Twelve variables were associated with this ED diagnosis, five of which had an odds ratio (OR) > 1.5: older age (13-17 vs 5-7 years, OR=2.9), longer time to presentation (>16 vs. <16 hours, OR=2.1), nausea (OR=1.7), sport mechanism (OR=1.7), and amnesia (OR=1.6). In those with physician-diagnosed concussion versus no concussion, the frequency of persistent symptoms was 62.5% vs. 38.8% (p<0.0001) at one week, 46.3% vs. 25.8% (p<0.0001) at two weeks and 33.0% vs. 23.0% (p<0.0001) at four weeks. Conclusion: Most children meeting international criteria for concussion were provided this diagnosis by the ED physician. There were five variables which increased the odds of this diagnosis by at least 1.5-fold. Relative to international criteria, the more selective assignment of concussion by ED physicians was associated with a greater frequency of persistent concussion symptoms. Nevertheless, many patients with alternative diagnoses exhibited persistent concussive symptoms at all time points. Clinicians should therefore weigh the benefits and risks of strictly applying the Zurich/Berlin international criteria versus individual discretion.

Introduction: Intravenous (IV) cannulation is commonly performed in emergency departments (ED), often causing substantial pain and distress. Distraction has been shown to reduce child-reported pain, but there is currently little published about the effects of using iPad technology as a distraction tool. Our primary objective was to compare the reduction of pain and distress using iPad distraction (games, movies, books of the child’s choice) in addition to standard care, versus standard care alone. Methods: This randomized clinical trial, conducted at the Stollery Childrens Hospital ED, recruited children between ages 6 to 11 years requiring IV cannulation. Study arm assignment was performed using REDCaps randomization feature. Due to the nature of the intervention, blinding was not possible for the children, parents or research and ED staff, but the data analyst was blinded to intervention assignment until completion of analysis. Pain, distress, and parental anxiety were measured using the Faces Pain Scale-Revised, the Observed Scale of Behavioural Distress-Revised, and the State Trait Anxiety Inventory, respectively. The pain scores and observed behavioural distress scores were compared using the Mann-Whitney U test. Other co-variates were analyzed using a linear regression analysis. Results: A total of 85 children were enrolled, with 42 receiving iPad distraction and 43 standard care, of which 40 (95%) and 35 (81%) children received topical anesthesia, respectively (p=0.09). There were 40 girls (47.1%) with a mean age of 8.32 +/− 1.61 years. The pain scores during IV cannulation (p=0.35) and the change in pain score during the procedure compared to baseline (p=0.79) were not significantly different between the groups, nor were the observed distress scores during IV cannulation (p=0.09), or the change in observed distress during the procedure compared to baseline (p=0.44). A regression analysis showed children in both groups had greater total behavioural stress if it was their first ED visit (p=0.01), had prior hospitalization experience (p=0.04) or were admitted to hospital during this visit (p=0.007). A previous ED visit, however, was predictive of a greater increase in parental anxiety from baseline (p=0.02). When parents were asked whether they would use the same methods to manage pain for their child, parents of the iPad group were more likely to say yes than were parents of the standard care group (p=0.03). Conclusion: iPad distraction during IV cannulation in school-aged children was not found to decrease pain or distress more than standard care alone, but parents preferred its use. The effects of iPad distraction may have been over-shadowed by potent topical anesthetic effect. Future directions include exploring iPad distraction for other age groups, and studying novel technology such as virtual reality and interactive humanoid robots.

Introduction: Bronchiolitis is a viral respiratory infection and the most common reason for hospitalization of infants. Despite evidence that few interventions are beneficial in patients with bronchiolitis, other studies would have shown that a significant proportion of patients undergo various forms of low value care. This objective of this project was to 1. establish baseline management of bronchiolitis in the Calgary Zone, and 2. deliver audit and feedback (A&F) reports to pediatric emergency physicians (PEP) to identify opportunities and strategies for practice improvement. Methods: This retrospective cohort study included all patients 12 months old that presented to a Calgary emergency department or urgent care center with a diagnosis of bronchiolitis from April 1, 2013 to March 31, 2017. Using data from various electronic health data sources, we captured age, vital signs, CTAS, common therapeutic interventions (bronchodilators, steroids, antibiotics) and investigations (chest x-ray (CXR), viral studies, antibiotics). Results were stratified by site and by admission status. Descriptive statistics were used to report baseline characteristics and interventions. Interhospital ranges (IHR) were provided to compare different hospitals in the zone. For the A&F component of the project, consenting PEP received a report of both their individual and peer comparator data and an in-person multi-disciplinary facilitated feedback session. Results: We included 4023 patients from all 6 sites (range from 28 to 3316 patients). Admission rates were 21.7% (IHR 0-29%). Mean age was 5.4 months old. Bronchodilator use was 27.0% (IHR 21-41%). 22.0% of patients received a CXR (IHR 0-57%) and 30.3% had viral studies done (IHR range 0.8-33%). PEP had higher usage of viral studies (30% vs 5.7%), whereas non-PEP had higher CXR usage (46.2% vs 23.4%). 41 of 66 PEP consented to receive their individual A&F reports (62%). In the facilitated feedback session PEP 1. identified two areas (bronchodilators and viral studies) where improvements could be made and 2. discussed specific strategies to decrease practice variation and minimize low value care including development of a multi-disciplinary care pathway, alignment with in-patient management, education and repeated A&F reports. Conclusion: Significant variability exists in management of patients with bronchiolitis across different hospitals in our zone. A facilitated feedback session identified areas for improvement and multi-disciplinary strategies to reduced low value care for patients with bronchiolitis. Future phases of this project include repeated data in 6 months and implementation of a provincial care pathway for the management of bronchiolitis.

Introduction: In children, acute otitis media (AOM) pain is undertreated. We sought to determine if video discharge instructions were associated with improved symptomatology, functional outcomes, and knowledge compared to a paper handout. Methods: We conducted a randomized controlled superiority trial comparing video discharge instructions (Easy Sketch Pro3TM) on management of pain to a paper handout detailing the same. We included caregivers of children 6 months to 5 years presenting to the emergency department (ED) with a clinical diagnosis of AOM. The primary outcome was symptomatology using the Acute Otitis Media Severity of Symptom (AOM SOS) score between 48 and 72 hours. The 7-item self-report AOM-SOS is scored from 0 to 13 with a higher score indicating more symptomatology. Secondary outcomes included knowledge gain using a 10-item survey, days of daycare/school/work missed, and recidivism. Assuming a minimal clinically important AOM-SOS difference of 2, 90% power, and 5% alpha, 60 individuals/group was needed. Results: 219 caregivers were randomized and 149 completed the 72-hour follow-up (72 paper and 77 video). The median (IQR) AOM-SOS score in the video group (adjusted for pre-intervention AOM-SOS, analgesic and antibiotic use) was significantly lower than paper [8 (7,11) versus 10 (7,13), respectively, p=0.004]. There were no significant differences between video and paper in the mean (SD) knowledge score [9.2 (1.3) versus 8.8 (1.8) correct answers, respectively, p=0.07], mean (SD) number that returned to a health provider [8/77 versus 10/72, respectively, p=0.49), mean (SD) number of daycare/schooldays missed [1.2 (1.5) versus 1.1 (2.1), respectively, p=0.62], and mean (SD) number of workdays missed by caregiver [0.5 (1) versus 0.8 (2), respectively, p=0.05]. Conclusion: Video discharge instructions are associated with less symptomatology compared to a paper handout, are effective for caregiver education in the ED, and should be used routinely.

Introduction: Substance and opioid misuse are growing public health concerns in Canada. Substance use disorders affect 21.6% of Canadians and accounted for $267 million in healthcare costs in 2011. Opioid misuse is a current public health crisis. The extent of the rise in substance and opioid misuse-related Emergency Department (ED) visits in Canada and the demographic groups in which the rise is concentrated have not been elaborated. Alberta has one of the most complete provincial ED visit records and provides an important understanding of national trends. The objective of this study was to evaluate trends in substance and opioid misuse-related ED visits in Alberta from 2010/11 to 2014/5 within demographic cross-sections of the population using administrative ED visit data from the National Ambulatory Care Reporting System (NACRS). Methods: All visits made by adult patients (18 years old) to any of more than 100 Albertan EDs for a substance misuse-related presentation between 2010/11 and 2014/15 were analyzed. Visits were classified as being related to substance or opioid misuse if the primary and/or secondary visit diagnoses were among an a priori determined group of ICD-10 codes. Annual substance misuse-related visits were compared as visits per 100,000 adult population in Alberta to standardize for population growth. Linear regression was used to assess whether ED visits increased significantly over time. A cross-sectional time-series analysis was employed to examine trends within subgroups defined by sex and age categories (18-29, 30-39, 40-49, 50-59, and 60 years) over a 60-month period. Results: 149,719 substance misuse-related visits were made by 65,089 patients and 8768 opioid misuse-related visits were made by 5763 patients. From 2010/11 to 2014/15, substance misuse-related ED visits in Alberta increased by 38% from 811 to 1119 visits per 100,000 population. Opioid misuse-related ED visits increased significantly (64%) from 44 to 72 per 100,000 population. Conversely, total ED visits per 100,000 population did not increase significantly. Substance and opioid misuse-related visits rose more in non-rural than rural areas. Cross-sectional time-series analysis showed that the greatest increase in substance and opioid misuse-related ED visits occurred in males and in the 18-29 year age category, in which visit increases for opioid misuse appeared exponential. Conclusion: Substance and opioid misuse-related ED visits increased significantly from 2010/11 to 2014/15 in Alberta, with the most dramatic increases occurring in young patients and males. These findings have important implications for targeting urgent preventative public health interventions to stem the rise of this epidemic.

Introduction: Emergency department (ED) stay and its associated conditions (immobility, inadequate hydration and nutrition, lack of stimulation) favor the development of delirium in vulnerable elderly patients. Poorly controlled pain, and paradoxically opioid pain treatment, has also been identified as a trigger for delirium. The aim of this study was to assess the relationship between pain, opioid treatment, and delirium in elderly ED patients. Methods: A multicenter prospective cohort study was conducted in four hospitals across the province of Québec (Canada). Patients aged 65 years old, waiting for care unit admission between February and May 2016, who were non-delirious upon ED arrival, independent or semi-independent for their activities of daily living, and had an ED stay of at least 8 hours were included. Delirium assessments were made twice a day for their entire ED stay and for the first 24 hours in the hospital ward using the Confusion Assessment Method (CAM). Pain intensity was evaluated using a visual analog scale (0-100) during the initial interview, and all opioid treatments were documented. Results: A total of 338 patients were included; 51% were female, mean age was 77 years (SD: 8). Forty-one patients (12%) experienced delirium during their hospital stay occurring within a mean delay of 47 hours (SD: 19) after ED admission. Among patients with pain intensity 60, 22% experienced delirium compared to 10.7% for patients with pain <60 (p<0.05). No significant association was found between opioid consumption and delirium (p=0.22). Logistic regression controlling for age, sex, ED stay duration, and opioids intake showed that patients with pain intensity 60 are 2.6 (95%CI: 1.2-5.9) more likely to develop delirium than patients who had pain <60. Conclusion: Severe pain, not opioids, is associated with the development of delirium during ED stay. Adequate pain control during the hospital stay may contribute to the decrease of delirium episodes.

Introduction: With hospital occupancy rates frequently approaching 100%, even small variations in daily admission numbers can have a large impact. The ability to predict variance in emergency admission rates would provide administrators with a significant advantage in managing hospital daily bed requirements. There is a growing interest in patterns of hospital admissions, and many EDs utilize historical admission patterns to attempt to predict daily bed requirements. Previous studies have utilized patient demographics and past medical history to develop an admission likelihood model. We wished to examine the predictive strength of individual CEDIS presenting complaints (PC) on admission likelihood Methods: Using a database analysis of over 285,000 ED presentations (2013-2017), we calculated visit frequencies and admission rates by PC. Using a logistic regression analysis PCs were ordered from high to medium predictive strength. Results: Of 285,155 presentations, there were 38,090 hospital admissions, a rate of 13.36%. Based on the number of visit frequencies and admission rates, the PCs demonstrating high predictive strength were Direct Referral (effect=0.36, binomial CI: 0.28 to 0.44); Shortness of Breath (0.32: 0.26 to 0.41); General Weakness; Weakness/Query CVA; & Chest Pain Cardiac Features (each 0.30: 0.25 to 0.42); Altered level of consciousness (0.24: 0.16 to 0.31); and Confusion (0.18: 0.08 to 0.26). With our sample size, all remaining CEDIS PCs had low predictive value (the effect is <0.1), or were not predictive at all. Conclusion: We have demonstrated that, for our population, certain PCs are associated with an increased likelihood of admission and have quantified this effect using logistic regression analysis. Variance from the average daily admission rate may be predicted, in our population, by identifying these PCs at registration.We plan to develop a tool, based on this data and implemented at registration, to predict cumulative likely daily admission requirements as patients present over a 24hr period.

Introduction: Situational awareness (SA) is essential for maintenance of scene safety and effective resource allocation in mass casualty incidents (MCI). Unmanned aerial vehicles (UAV) can potentially enhance SA with real-time visual feedback during chaotic and evolving or inaccessible events. The purpose of this study was to test the ability of paramedics to use UAV video from a simulated MCI to identify scene hazards, initiate patient triage, and designate key operational locations. Methods: A simulated MCI, including fifteen patients of varying acuity (blast type injuries), plus four hazards, was created on a college campus. The scene was surveyed by UAV capturing video of all patients, hazards, surrounding buildings and streets. Attendees of a provincial paramedic meeting were invited to participate. Participants received a lecture on SALT Triage and the principles of MCI scene management. Next, they watched the UAV video footage. Participants were directed to sort patients according to SALT Triage step one, identify injuries, and localize the patients within the campus. Additionally, they were asked to select a start point for SALT Triage step two, identify and locate hazards, and designate locations for an Incident Command Post, Treatment Area, Transport Area and Access/Egress routes. Summary statistics were performed and a linear regression model was used to assess relationships between demographic variables and both patient triage and localization. Results: Ninety-six individuals participated. Mean age was 35 years (SD 11), 46% (44) were female, and 49% (47) were Primary Care Paramedics. Most participants (80 (84%)) correctly sorted at least 12 of 15 patients. Increased age was associated with decreased triage accuracy [-0.04(-0.07,-0.01);p=0.031]. Fifty-two (54%) were able to localize 12 or more of the 15 patients to a 27x 20m grid area. Advanced paramedic certification, and local residency were associated with improved patient localization [2.47(0.23,4.72);p=0.031], [-3.36(-5.61,-1.1);p=0.004]. The majority of participants (78 (81%)) chose an acceptable location to start SALT triage step two and 84% (80) identified at least three of four hazards. Approximately half (53 (55%)) of participants designated four or more of five key operational areas in appropriate locations. Conclusion: This study demonstrates the potential of UAV technology to remotely provide emergency responders with SA in a MCI. Additional research is required to further investigate optimal strategies to deploy UAVs in this context.

Introduction: Paroxysmal supraventricular tachycardia (PSVT) is a common group of arrhythmias that Advanced Care Paramedics (ACPs) can often manage with vagal maneuvers, adenosine, and/or cardioversion, provided that they correctly identify the rhythm. The purpose of this study is to determine the accuracy of ACP identification of PSVT. Methods: Following ethics approval, all calls for patients 18 years with a 12-lead ECG available, who were assessed by ACPs within a region of western Ontario between July 2015 - December 2015 and had a documented heart rate>150bpm, were included. Paramedic call reports were retrospectively reviewed for study data, including documentation of ACP identified PSVT. The reference standard was consensus between an EMS fellow and prehospital physician who adjudicated each ECG for the presence of PSVT in a blinded, independent fashion. In the event of a disagreement, a third, blinded prehospital physician was used for consensus. Results: Of the 442 patients included, 197 (45%) were male and the median age [Interquartile range(IQR)] was 70.0 (58.0-82.8). ACPs identified 74 (16.7%) patients as having PSVT while 38 (8.6%) were identified by physicians as having PSVT. 44.7% of patients with physician identified PSVT had a history of previous arrhythmia, compared to 30.9% of patients with no physician identified PSVT (p=0.10). They were also significantly younger 58.5 (48.5-72.0) compared to those without physician identified PSVT 69.0 (60.0-84.0) (P=0.0010). Sensitivity of ACP identified PSVT was 97.4% (95%CI:86.2%-99.9%) and specificity was 90.8% (95%CI:87.6%-93.5%). The positive predictive value (PV) of ACP identified PSVT was 50.0% (95%CI:42.3%-57.7%), the negative PV was 99.7% (95%CI:98.1%-99.9%), the positive likelihood ratio (LR) was 10.6 (95%CI:7.8-14.5) and negative LR was 0.03 (95%CI:0.0-0.2). Moderate inter-rater agreement was seen between initial ECG interpretations (kappa= 0.42, 95%CI:0.29-0.54) by the fellow and prehospital physician, while agreement was higher (good) between the two prehospital physicians (kappa=0.76, 95%CI:0.55-0.96). Conclusion: These results indicate that ACPs are adept at identifying PSVT, but are prone to false positives. Given the relatively good sensitivity and specificity seen in this investigation, future studies should investigate ACP recognition of specific rare arrhythmias (antidromic accelerated atrial fibrillation) that may require different management including avoidance of adenosine.