Is there still a role for neurosurgery in psychiatry in 2015?
Proof-of-concept work by a Korean team1 assessed a novel,
minimally invasive, non-cranium-opening technique in four patients with
refractory obsessive–compulsive disorder (OCD). With just local anaesthetic
to the scalp, magnetic resonance-guided focused ultrasound (MRgFUS) was
utilised to thermally ablate the anterior limb of the internal capsule
bilaterally. Unlike many other invasive procedures, this neuroimaged
technique affords real-time monitoring of lesion induction and the patient's
neurological and psychological status. The treated individuals showed a
gradual improvement in their OCD, with mean symptom reductions of about a
third over the 6-month follow-up period, and almost immediate and sustained
improvements in depressive and anxiety symptoms. No neuropsychiatric
sequalae were seen in this limited sample, which certainly compares
favourably with existing techniques. Psychosurgery evokes unsavoury images
of the past, and it is uncertain how much will there is for such work: in an
evidence-based profession, let the data lead.