Hostname: page-component-78c5997874-8bhkd Total loading time: 0 Render date: 2024-11-10T13:01:24.514Z Has data issue: false hasContentIssue false
  • English
  • Français

REM sleep, hippocampus, and memory processing: Insights from functional neuroimaging studies

Published online by Cambridge University Press:  21 November 2013

Victor I. Spoormaker ,
Michael Czisch  and
Florian Holsboer
Victor I. Spoormaker
Affiliation:
Max Planck Institute of Psychiatry, D-80804 Munich, Germany. spoormaker@mpipsykl.mpg.deczisch@mpipsykl.mpg.deholsboer@mpipsykl.mpg.dehttp://www.mpipsykl.mpg.de
Michael Czisch
Affiliation:
Max Planck Institute of Psychiatry, D-80804 Munich, Germany. spoormaker@mpipsykl.mpg.deczisch@mpipsykl.mpg.deholsboer@mpipsykl.mpg.dehttp://www.mpipsykl.mpg.de
Florian Holsboer
Affiliation:
Max Planck Institute of Psychiatry, D-80804 Munich, Germany. spoormaker@mpipsykl.mpg.deczisch@mpipsykl.mpg.deholsboer@mpipsykl.mpg.dehttp://www.mpipsykl.mpg.de
Get access Rights & Permissions [Opens in a new window]

Abstract

Neuroimaging studies show that episodic memory encoding is associated with increased activity in hippocampus and lateral prefrontal cortex; however, the latter structure shows decreased activity in rapid eye movement (REM) sleep. Together with few episodic memory traces in REM sleep, and REM sleep deprivation affecting hippocampus-independent emotional processes, this argues for generic information processing in REM sleep rather than linking episodic memory traces.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 36 , Issue 6 , December 2013 , pp. 629 - 630
Copyright
Copyright © Cambridge University Press 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Baylor, G. W. & Cavallero, C. (2001) Memory sources associated with REM and NREM dream reports throughout the night: A new look at the data. Sleep 24(2):165–70.Google Scholar
Braun, A. R., Balkin, T. J., Wesensten, N. J., Carson, R. E., Varga, M., Baldwin, P., Selbie, S., Belenky, G. & Herscovitch, P. (1997) Regional cerebral blood flow throughout the sleep–wake cycle: An H2 15O PET study. Brain 120:1173–97.Google Scholar
Buckner, R. L., Andrews-Hanna, J. R. & Schacter, D. L. (2008) The brain's default network: Anatomy, function, and relevance to disease. Annals of the New York Academy of Sciences 1124:1–38.CrossRefGoogle ScholarPubMed
Cai, D. J., Mednick, S. A., Harrison, E. M., Kanady, J. C. & Mednick, S. C. (2009) REM, not incubation, improves creativity by priming associative networks. Proceedings of the National Academy of Sciences USA 106(25):10130–34.CrossRefGoogle Scholar
Diekelmann, S. & Born, J. (2010) The memory function of sleep. Nature Reviews Neuroscience 11:114–26.Google Scholar
Grosmark, A. D., Mizuseki, K., Pastalkova, E., Diba, K. & Buzsáki, G. (2012) REM sleep reorganizes hippocampal excitability. Neuron 75(6):1001–1007.CrossRefGoogle ScholarPubMed
Lewis, P. A. & Durrant, S. J. (2011) Overlapping memory replay during sleep builds cognitive schemata. Trends in Cognitive Sciences 15:343–51.CrossRefGoogle ScholarPubMed
Maguire, E. A., Valentine, E. R., Wilding, J. M. & Kapur, N. (2003) Routes to remembering: The brains behind superior memory. Nature Neuroscience 6(1):90–95.Google Scholar
Maquet, P., Peters, J., Aerts, J., Delfiore, G., Degueldre, C., Luxen, A. & Franck, G. (1996) Functional neuroanatomy of human rapid-eye-movement sleep and dreaming. Nature 383(6596):163–66.Google Scholar
Montgomery, S. M., Sirota, A. & Buzsáki, G. (2008) Theta and gamma coordination of hippocampal networks during waking and rapid eye movement sleep. Journal of Neuroscience 28:6731–41.Google Scholar
Silvestri, A. J. (2005) REM sleep deprivation affects extinction of cued but not contextual fear conditioning. Physiology and Behavior 84:343–49.Google Scholar
Spaniol, J., Davidson, P. S., Kim, A. S., Han, H., Moscovitch, M. & Grady, C. L. (2009) Event-related fMRI studies of episodic encoding and retrieval: Meta-analyses using activation likelihood estimation. Neuropsychologia 47(8):1765–79.CrossRefGoogle ScholarPubMed
Spoormaker, V. I., Schröter, M. S., Gleiser, P. M., Andrade, K. C., Dresler, M., Wehrle, R., Sämann, P. G. & Czisch, M. (2010) Development of a large-scale functional brain network during human non-rapid eye movement sleep. Journal of Neuroscience 30(34):11379–87.Google Scholar
Wehrle, R., Kaufmann, C., Wetter, T. C., Holsboer, F., Auer, D. P., Pollmächer, T. & Czisch, M. (2007) Functional microstates within human REM sleep: First evidence from fMRI of a thalamocortical network specific for phasic REM periods. European Journal of Neuroscience 25:863–71.Google Scholar