B-vitamins affect brain function through multiple pathways. Given limited evidence on the relationship between dietary intake of these vitamins and psychological disorders, we examined dietary intake of vitamin B6-9-12 in relation to psychological disorders among Iranian women.

Cross-sectional study. Dietary intake was assessed using a valid and reliable FFQ. To assess psychological disorders, we used a version of the Depression Anxiety Stress Scale-21 validated in Iran.

Ten public health centres in southern Tehran, Iran.

A total of 447 female participants aged 20–50 years.

The median values of vitamin B6 (pyridoxine), B9 (folate) and B12 (cobalamin) were 1·30 mg/d, 313·89 µg/d and 3·99 µg/d, respectively. After adjustment for potential confounders, dietary vitamin B6 intake was associated with lower odds of depression (OR: 0·54; 95 % CI: 0·31, 0·95; Ptrend: 0·03). However, there was a positive association between dietary vitamin B12 intake with the odds of depression (OR: 2·05; 95 % CI: 1·17, 3·60; Ptrend: 0·01) and psychological distress (OR: 2·00; 95 % CI: 1·17, 3·41; Ptrend: 0·01). No association was found between vitamin B9 with any psychological disorders.

Women with higher dietary intakes of vitamin B6 had lower likelihood of depression. However, women with higher dietary intake of vitamin B12 had higher odds of depression and psychological distress. Future prospective studies in different populations are needed to clarify whether B-vitamin deficiency is a cause or consequence of psychological disorders.

Psychological disorder such as anxiety and depression have been related to increased mortality in both healthy individuals and medical patients. This study has been done for evaluation of prevalence of anxiety and depression and comparison with a control group (A&E's patients 1.

We checked three hundred patients of internal medicine and A&E (as a control group) department. They have chosen by a Purposive accessible sampling method. The psychopathological profile was assessed using the SCL-90 questionnaire by Iranian version. Data have been computed and analyzed by SPSS V.17 and we used Student t test for parametric variables and Mann-Whitney for the analysis of nonparametric variables and Linear regression was used to identify the impact of independent variables. The results have been considered significant when the two tailed p-value was less than 0.05.

In internal ward 69.3% and A&E department 42% of patient have had depression (OR= 3.5; 95% CI, 1.9 to 6.5). Anxiety were observed in 50.7% of internal medicine patients and 12% of A&E's patients (OR= 1.94; 95% CI, 5.1 to 23.7).

Prevalence of the depression and anxiety in internal ward patients was significantly higher in compare to A&E's patients. Therefore, it's necessary to consider these patients in order to diagnosing for the early treatment.

Negative emotions such as anxiety and depression have been related to increased mortality in both healthy individuals and medical patients The method of treatment would be changed when the patients have psychological problem. In internal ward researcher observed many patients that them shown psychiatric disorder such as depression and anxiety. Therefore, this study has been done for evaluation of prevalence of anxiety and depression and comparison with a control group.

In this cross-sectional study, we checked 150 patients of internal medicine department and 150 patients, who have admitted to the A&E department as a control group. They have chosen by a Purposive accessible sampling method. A questionnaire form, namely “SCL-R-90” was filled by a group of nursing student. This is known as a standardized questionnaire in Iran. Data have been computed and analyzed by SPSS V.13 and we used t-student, Mann-Whitney tests and logistic regression methods. The results have been considered significant when the two tailed p-value was less than 0.05.

In internal ward 69.3% and A&E department 42% of patient have had depression (OR=3.5, 95%CI=1.9—6.5). Anxiety were observed in 50.7%of internal medicine patients and 12% of A&E's patients (OR=1.94, 95%CI=5.1 —23.7).

Prevalence of the depression and anxiety in internal ward patients was significantly higher in compare to A&E's patients. Therefore, it's necessary to consider these patients in order to diagnosing for the early treatment. Recommendation are made to further investigate by greater sample size and different setting in this field is warranted.