Operationalization guidance is needed to support health technology assessment (HTA) bodies considering implementing lifecycle HTA (LC-HTA) approaches. The 2022 Health Technology Assessment International (HTAi) Global Policy Forum (GPF) established a Task Force to develop a position paper on LC-HTA. In its first paper, the Task Force established a definition and framework for LC-HTA in order to tailor it to specific decision problems. This second paper focused on the provision of practical operational guidance to implement LC-HTA. Detailed descriptions of the three LC-HTA operational steps are provided (defining the decision problem, sequencing of HTA activities, and developing optimization criteria) and accompanied by worked examples and an operationalization checklist with 20 different questions for HTA bodies to consider when developing an LC-HTA approach. The questions were designed to be applicable across different types of HTA and scenarios, and require adaptation to local jurisdictions, remits, and context.

Nutritional requirements of individuals vary across the lifecycle, according to activity, age and gender. To optimize human health, consideration of nutritional priorities at each stage is needed. This conference brought together multidisciplinary experts in maternal and child nutrition and health, cardiometabolic and plant-based nutrition and dietitians involved in the care of vulnerable populations, plus nutritional metabolism, health and ageing. The presentations highlighted the most important nutrition research in these areas, updating knowledge and suggesting how dietary advice and policy could be adapted to incorporate research findings. With the global increase in non-communicable disease (NCD) and nutrition being considered as a key modifiable risk factor for the prevention and management of NCD, this conference was much needed.

Machine learning (ML) is increasingly used to enhance intelligent products in the field of product design. However, ML has a never-ending lifecycle in which its capabilities and technical properties iteratively change as new annotated data are utilized. The never-ending lifecycle of ML (which includes data annotation, model training, and other steps) has led to challenges to the prototyping of ML-enhanced products and requires a high level of ML literacy in designers. To facilitate the prototyping of ML-enhanced products and improve the ML literacy of designers, we draw inspiration from a design method called Material Lifecycle Thinking (MLT), which regards ML as a continuously evolving design material. Based on the MLT, we proposed a cyclical prototype workflow and developed inML Kit, a toolkit enabling designers to make functional ML prototypes and improve ML literacy by involving them in the never-ending ML lifecycle. The toolkit was designed, iterated, and implemented through the participatory design process with experienced designers in this field. We evaluated inML Kit by conducting a controlled user study where our toolkit was compared with Google AIY. The evaluation results imply that our inML Kit helps designers to make functional ML prototypes while improving their ML literacy.

Grain refinement has been applied to enhance the materials strength for miniaturization and lightweight design of nuclear equipment. It is critically important to investigate the low-cycle fatigue (LCF) properties of grain refined 316LN austenitic stainless steels for structural design and safety assessment. In the present work, a series of fine-grained (FG) 316LN steels were produced by thermo-mechanical processes. The LCF properties were studied under a fully reversed strain-controlled mode at room temperature. Results show that FG 316LN steels demonstrate good balance of high strength and high ductility. However, a slight loss of ductility in FG 316LN steel induces a significant deterioration of LCF life. The rapid energy dissipation in FG 316LN steels leads to the reduction of their LCF life. Dislocations develop rapidly in the first stage of cycles, which induces the initial cyclic hardening. The dislocations rearrange to form dislocations cell structure resulting in cyclic softening in the subsequent cyclic deformation. Strain-induced martensite transformation appears in FG 316LN stainless steels at high strain amplitude (Δε/2 = 0.8%), which leads to the secondary cyclic hardening. Moreover, a modified LCF life prediction model for grain refined metals predicts the LCF life of FG 316LN steels well.

To solve the poor cyclability of faradic supercapacitors (SCs), the authors reported a unique porous carbon (PC) coating with “gap shell” structure on carbon fiber cloth (CFC)/NiS2 materials. This gap shell PC coating was fabricated by combining atomic layer deposition (ALD) Al2O3 and molecular layer deposition alucone, followed by carbonization and etching. The as-prepared CFC/NiS2/PC composites were directly used as binder-free electrodes for SCs. Benefited from its novel nanostructure, the CFC/NiS2/PC electrode shows a large specific capacitance of 1034.6 F/g at 1 A/g and considerable rate capability of 67% capacitance, retaining ratio within 1–20 A/g. The cyclability of the CFC/NiS2/PC electrode is enhanced by 50% relative to the mere CFC/NiS2 after 2000 cycles, which is attributed to the gap and electrically conductive PC coating. Hence, this work provides a promising approach to design gap shell layer for improved cyclability of faradic SCs and other practical applications in energy storage electronics.

Using novel microdata, we explore lifecycle consumption in Sub-Saharan Africa. We find that households' ability to smooth consumption over the lifecycle is large, particularly, in rural areas. Consumption in old age is sustained by shifting to self-farmed staple food, as opposed to traditional savings mechanisms or food gifts. This smoothing strategy indicates two important costs. The first cost is a loss of human capital as children seem to be diverted away from school and into producing self-farmed food. Second, a diet largely concentrated in staple food (e.g., maize in Malawi) in old age results in a loss of nutritional quality for households headed by the elderly.

There is a huge variety of modular product designs for smartphones (concept studies, prototypes, products on the market), and a similarly high variety of circular economy aspects related to these different design approaches. Modularity requires initially more material input but pays off as the consumer is embracing the possibilities of modularity. Key materials for modularity features are gold, beryllium, and neodymium, etc.

On the example of smartphones modularity as a strategy for circular design is analyzed in detail. Modularity of products is a design trend, which is supposed to facilitate reparability, recyclability, and/or upgradeability. However, modularity requires some design changes. The most evident design change is the need for connectors to provide mechanical and electrical contact between individual modules. Depending on the nature and use scenario of a connector reliability, robustness, wear resistance, and non-reactive surfaces are required. The paper explains different modularity approaches for smartphones, some of these being already available in the market, others are still in a conceptual phase. Analyzing technologies for modularity leads to a group of “modularity materials,” which are essential for such circular design approaches, but at the same time are among those materials with a large environmental footprint or limited recyclability. A life cycle assessment of a modular smartphone shows a roughly 10% higher environmental life cycle impact compared with a conventional design. This needs to be compensated by reaping the circular economy benefits of a modular design, i.e., higher likeliness of getting a broken device repaired, extending the lifetime through hardware upgrades and refurbishment.

In this work, the evaluation of the growth of cracks in specimens of square cross section requested by symmetrical cyclic torsion moments was performed. The specimens were manufactured from AISI 1015. A pre-crack was machined on one side to induce the crack growth. The crack length with the increase in the number of cycles was measured by means of penetrating liquids method. By means of the Finite Element Method, the stress – strain state of the specimens was simulated. The displacements in the crack tip were determined to apply the technique of the Crack Tip Opening Displacements to calculate the Stress Intensity Factor. The calculated Stress Intensity Factor was related to the dimensions of the specimen and the size of the crack to propose an equation for the shape function.

Today, processing technologies have generated negative environmental impact as emission of toxic gases and degradation of the earth when certain products are placement in landfills leading to environmental pollution and several health risks, which damage societies to sustain the planet for future generations. As electronics waste, grain-oriented iron foils, graphite films and Mn-Zn ferrites have been identified as interesting candidates. Uncommon physical properties from such materials are available when these are converting technologically. A strategy such as Life-Cycle Assessment is employed here to taking into account all stages of the life cycle of electronics waste, including processing technology, manufacturing processes, use phase, and end-of-life routes to quantify the recycling performance as a function of the physical parameters that will characterize operability of a functional device. Hence, structure and conduction properties in waste materials are exploring by using Raman spectroscopy and electrical characterization techniques. Researching waste materials will provide theoretical basis for open-loop recycling, where trends related to green engineering must be attained with recyclable materials for practical adaptive structures using different performance principles compared to those used in silicon devices.

In this article, we investigate a possible conflict between two core objectives of cooperatives, members’ income, and continuity, by examining the link between debt and the price paid to producers for Bordeaux wine cooperatives, according to their downstream strategies: (1) the traditional strategy, which is to sell wine in bulk to négociants; (2) joining a federation of cooperatives which blends and puts the wine in the retail market; and (3) vertical integration. We show that downstream strategies are related to different lending regimes, making the relationship between banks and cooperatives a key issue for the lifecycle of cooperatives. (JEL Classifications: D230, G320, Q130)

Concerted efforts by stakeholders could overcome the hurdles and enable a viable recycling system for automotive LIBs by the time many of them go out of service.

Lithium-ion batteries (LIBs) were commercialized in the early 1990s and gained popularity first in consumer electronics, then more recently for electric vehicle (EV) propulsion, because of their high energy and power density and long cycle life. Their rapid adoption brings with it the challenge of end-of-life waste management. There are strong arguments for LIB recycling from environmental sustainability, economic, and political perspectives. Recycling reduces material going into landfills and avoids the impacts of virgin material production. LIBs contain high-value materials like cobalt and nickel, so recycling can reduce material and disposal costs, leading to reduced EV costs. Battery recycling can also reduce material demand and dependence on foreign resources, such as cobalt from Democratic Republic of the Congo, where much production relies on armed aggression and child labor.

Several companies are finding ways to commercialize recycling of the increasingly diverse LIB waste stream. Although Pb-acid battery recycling has been successfully implemented, there are many reasons why recycling of LIBs is not yet a universally well-established practice. Some of these are technical constraints, and others involve economic barriers, logistic issues, and regulatory gaps. This paper first builds a case as to why LIBs should be recycled, next compares recycling processes, and then addresses the different factors affecting LIB recycling to direct future work towards overcoming the barriers so that recycling can become standard practice.

While there may be an important, but transitory, cyclical component in the poor performance of the past decade, we will emphasise the secular forces: the impact of demographic structure and innovation. We draw on the empirical and theoretical work reported in Aksoy, Basso, Smith and Grasl (2015), ABSG, about the impact of changes in demographic structure on macroeconomic outcomes. This suggests that changes in age profile not only have significant implications for savings, investment, real interest rates and growth but also for innovation. The size of the effects seems plausible. For instance, if in 2015 the UK had the 1970 age structure, it would have added 0.68 percentage points to the long-run annual growth rate. The model suggests that the population ageing predicted for the next decades will tend to reduce output growth and real interest rates across OECD countries.

First investigation on the relationship between reproductive development and estimated age/size in a wild population of Octopus vulgaris was performed in the Sardinian waters (central western Mediterranean Sea) in order to have a useful tool for integral fishing management in the area. Full sexual maturity was registered from April to August for females with a peak in summer whereas for males it was observed all year round. Size at maturity was 320 g for males (70 mm dorsal mantle length (ML)) and 520 g for females (120 mm ML). From 61 to 465 and from 80 to 390 daily growth increments were counted on the lateral wall of the upper beak, respectively in males and females, obtaining a positive relationship between estimated age and size of the specimens. The sexual maturation was primarily size-dependent with a secondary role played by the age especially in males. The estimated age of 390 and 465 days respectively of the largest female (4661 g) and male (5344 g) as well as that of two males at the end of their lives (‘spent’) of 310 and 420 days old, have suggested a lifecycle of about 1 year for both genders.

We suggest two supplements to Franco Modigliani's lifecycle model in order to explain why people who have retired from paid work choose either to start volunteering or increase the amount of time they devote to volunteer work. First, total consumption consists of both the material and immaterial products of work. While people can save their income in order to maintain an even level of material consumption, they unable to save a portion of the immaterial product. Second, at the statutory retirement age people retire only from paid work. We argue that older people substitute paid work for volunteering due to their inherent need to maintain immaterial consumption during retirement.