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Simulations of enhanced malaria transmission and host bias induced by modified vector blood location behaviour

Published online by Cambridge University Press:  06 April 2009

P. A. Rossignol  and
A. Mackay Rossignol
P. A. Rossignol
Affiliation:
Division of Geographic Medicine and Infectious Diseases, Tufts University School of Medicine, Boston, MA 02111
A. Mackay Rossignol
Affiliation:
Department of Civil Engineering, Environmental Health Program, Tufts University, Medford, MA 02155
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Summary

Monte Carlo simulations were developed to assess the potential impact of parasite pathology on vector salivary function as well as of host haemostasis on transmission. Assuming that a proportion of desisting vectors switch host following failure to locate blood, we demonstrate three possible consequences: (1) infected vectors contact more hosts than non-infected hosts, (2) non-infected vectors are biased to infected hosts, independently of attraction, and (3) an exponential relationship exists between parasite load and transmission. We discuss possible epidemiological implications.

Information

Type
Research Article
Information
Parasitology , Volume 97 , Issue 3 , December 1988 , pp. 363 - 372
Copyright
Copyright © Cambridge University Press 1988

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