This paper considers the complex entanglements from which stones and stone craftspeople emerged in the precolonial Maya world. Drawing from recent scholarship that emphasizes the relational and processual nature of making and knowing, it adopts a multi-practice perspective to explore how humans transformed limestone into knowable and workable materials and how, in turn, limestone transformed humans into knowledgeable and skilled individuals. Geoarchaeological, archaeometric, and experimental data from the central and northern Maya lowlands are combined to identify choices and preferences in selecting, extracting, and processing calcareous materials, and to examine what these reveal about past knowledge and skills. We then turn our attention to the ways in which quarry workers, lime producers, and toolmakers learned to work with stone. We argue that becoming attuned to limestone was a sociomaterial process that involved repeated interactions with both material elements and social actors. Our discussion highlights the active role of limestone not only in shaping learning experiences but also in facilitating connections between diverse practices, and thus contributing to a dynamic, interconnected landscape of knowledge.