This article provides a new perspective on EU exit as an exemplary form of disruptive dissensus or extreme Euroscepticism by examining how it is shaped by people’s attitudes towards the Union’s actions during the COVID-19 pandemic. We test how the dissatisfaction about how the EU handled the pandemic limited the trust in how it would manage it in the future, and influences a preference to exit the EU. We use a multi-level statistical model which combines individual-level data from a Eurobarometer survey and country-level characteristics from all 27 EU member states. The results indicate that disruptive dissensus is linked to both the retrospective and prospective attitudes towards the EU policy initiatives, even when controlling for the severity of the pandemic as well as the populists in government at the country level. We also find that the link between specific and diffuse support at the EU level holds during crises.