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1 results

  • Hypoglossal nerve stimulation in patients outside the STAR trial criteria: a systematic review

  • Pamela Lim Tze Xin, Chuan Hao Gui, Soon Heng Terry Tan
  • Journal:
    The Journal of Laryngology & Otology , First View
    Published online by Cambridge University Press:
    31 March 2025, pp. 1-11
    • Article
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  • Objectives

    This study aimed to evaluate if there is a role for hypoglossal nerve stimulation outside the original Stimulation Therapy for Apnea Reduction (STAR) trial criteria.

    Methods

    This review was conducted using PubMed, Embase and Cochrane Library databases.

    Results

    Hypoglossal nerve stimulation led to improved outcomes in individuals who fell outside the STAR trial criteria for apnoea-hypopnoea index and body mass index. However, this improvement did not extend to patients with complete concentric palatal collapse or those with a significant central apnoea component.

    Conclusion

    Hypoglossal nerve stimulation can be effective in patients outside the original STAR trial criteria for certain parameters. Further research is needed to refine patient selection criteria for optimal outcomes.