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4b - A Developmental Psychopathology Perspective on the Emergence of Antisocial and Borderline Personality Pathologies across the Lifespan: Commentary on Personality Pathology in Youth

from Part I - Etiology

Published online by Cambridge University Press:  24 February 2020

By
Theodore P. Beauchaine
Edited by
Carl W. Lejuez  and
Kim L. Gratz
Carl W. Lejuez
Affiliation:
University of Kansas
Kim L. Gratz
Affiliation:
University of Toledo, Ohio
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Summary

Traditionally, studies of personality disorder development have focused on (1) whether adult symptoms are expressed among children and adolescents, and if so (2) ages of onset at which full syndrome criteria are met. Although such studies are necessary and important, they provide limited understanding of etiopathophysiology—the complex and interactive biological and social determinants of PDs across the lifespan. This commentary presents a brief update to our conceptual model of antisocial (ASPD) and borderline (BPD) development among boys and girls. It focuses on (1) complexity of genetic, environmental, and neurohormonal influences on subcortical vulnerability to impulsivity; (2) increasing contributions of cortically mediated emotion dysregulation in adolescence and adulthood; and (3) moderation of common genetic and neural vulnerabilities to ASPD and BPD by sex. Importantly, neural correlates of ASPD and BPD are already observed among teens who are at risk for the disorders. Implications for prevention are discussed.

Keywords

borderlineantisocialpersonality disorderdevelopmentcorticalsubcorticalpsychopathologyimpulsivityemotion dysregulation
Type
Chapter
Information
The Cambridge Handbook of Personality Disorders , pp. 94 - 98
Publisher: Cambridge University Press
Print publication year: 2020

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