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5 - Assisted reproductive technology for preserving fertility in women with cancer

from SECTION 2 - Fertility Issues and Paediatric Cancers

Published online by Cambridge University Press:  05 October 2014

By
Shaun Fountain
Edited by
Sean Kehoe ,
Eric Jauniaux ,
Pierre Martin-Hirsch  and
Philip Savage
Shaun Fountain
Affiliation:
Salisbury District Hospital
Sean Kehoe
Affiliation:
John Radcliffe Hospital, Oxford
Eric Jauniaux
Affiliation:
University College Hospital, London
Pierre Martin-Hirsch
Affiliation:
Royal Preston Hospital
Philip Savage
Affiliation:
Charing Cross Hospital, London
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Summary

Assisted reproductive techniques (ART) that can help women under the age of 40 years are: in vitro fertilisation (IVF) with embryo cryopreservation; ovarian stimulation with mature oocyte cryopreservation; and ovarian tissue banking. Cryopreservation of embryos, oocytes or ovarian tissue is indicated where treatment for cancer is likely to lead to significant damage to the ovaries and reduction in subsequent fertility. Ovarian tissue cryopreservation, which shows great promise for female fertility preservation, is not an established technique and should be considered to be investigational. Embryo, sperm and oocyte storage is licensed by the Human Fertilisation and Embryology Authority (HFEA), which requires infection screening of the gamete and embryo providers. This chapter discusses the cryopreservation methods for each method of fertility preservation. Orthotopic transplantation can be performed laparoscopically or as an open procedure. Consent for all these procedures should be fully informed and the women should have access to specialist counseling.

Keywords

orthotopic transplantationinformed consentIVFovarian stimulationovarian tissue bankingwomenembryo cryopreservationfertility preservationassisted reproductive technologycancer
Type
Chapter
Information
Cancer and Reproductive Health , pp. 63 - 72
Publisher: Cambridge University Press
Print publication year: 2008

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