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Chapter 17 - Management of Monoamniotic Twins

Published online by Cambridge University Press:  11 October 2022

Leanne Bricker
Affiliation:
Corniche Hospital, Abu Dhabi
Julian N. Robinson
Affiliation:
Brigham & Women's Hospital, Boston
Baskaran Thilaganathan
Affiliation:
St George's Hospital Medical School, University of London
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Summary

In monochorionic monoamniotic twin pregnancies, two fetuses share a single placenta and a single amniotic cavity. This unique anatomic configuration, although rare, puts them at high risk for a number of complications including structural anomalies, twin-twin transfusion syndrome, selective intra-uterine growth restriction and cord accidents. Early diagnosis and patient counselling are therefore crucial. Level 1 evidence on the optimal management of monoamniotic twins is lacking, but observational studies provide some guidance for best practice. In uncomplicated monoamniotic twins, after viability, fetal mortality is less than 5% if close surveillance is initiated. This can be done in either an inpatient or outpatient setting. If all goes well, monoamniotic twins should be delivered from 33 weeks’ gestation as, at that timepoint, the risk of in utero death is larger than the risk of (non-respiratory) neonatal complications.

Type
Chapter
Information
Management of Multiple Pregnancies
A Practical Guide
, pp. 181 - 187
Publisher: Cambridge University Press
Print publication year: 2022

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References

Glinianaia, SV, Rankin, J, Khalil, A et al. Prevalence, antenatal management and perinatal outcome of monochorionic monoamniotic twin pregnancy: a collaborative multicenter study in England, 2000–2013. Ultrasound Obstet Gynecol 2019;53:184–92.Google Scholar
Knopman, JM, Krey, LC, Oh, C, Lee, J, McCaffrey, C, Noyes, N. What makes them split? Identifying risk factors that lead to monozygotic twins after in vitro fertilization. Fertil Steril 2014 Jul;102(1):82–9.CrossRefGoogle ScholarPubMed
Fenton, C, Reidy, K, Demyanenko, M, Palma-Dias, R, Cole, S, Umstad, MP. The significance of yolk sac number in monoamniotic twins. Fetal Diagn Ther 2019;46(3):193–9.CrossRefGoogle ScholarPubMed
Allen, VM, Windrim, R, Barrett, J, Ohlsson, A. Management of monoamniotic twin pregnancies: a case series and systematic review of the literature. BJOG 2001 Sep;108(9):931–6.Google Scholar
Van Mieghem, T, De Heus, R, Lewi, L et al. Prenatal management of monoamniotic twin pregnancies. Obstet Gynecol 2014 Sep;124(3):498506.Google Scholar
Hack, KE, Van Gemert, MJ, Lopriore, E et al. Placental characteristics of monoamniotic twin pregnancies in relation to perinatal outcome. Placenta 2009 Jan;30(1):62–5.CrossRefGoogle ScholarPubMed
Murgano, D, Khalil, A, Prefumo, F et al. Outcome of twin-to-twin transfusion syndrome in monochorionic monoamniotic twin pregnancies: a systematic review and meta-analysis. Ultrasound Obstet Gynecol 2019 Oct 8. https://doi.org/10.1002/uog.21889Google Scholar
Saccone, G, Khalil, A, Thilaganathan, B et al. Weight discordance and perinatal mortality in monoamniotic twin pregnancies: analysis of the MONOMONO, NorSTAMP and STORK multiple pregnancy cohorts. Ultrasound Obstet Gynecol 2020 March 27;55(3):332–8.Google Scholar
Litwinska, E, Syngelaki, A, Cimpoca, B, Frei, L, Nicolaides, KH. Outcome of twin pregnancies with two live fetuses at 11–13 weeks’ gestation. Ultrasound Obstet Gynecol 2019 Oct 15. https://doi.org/10.1002/uog.21892CrossRefGoogle Scholar
Madsen, C, Søgaard, K, Zingenberg, H et al. Outcomes of monoamniotic twin pregnancies managed primarily in outpatient care: a Danish multicenter study. Acta Obstet Gynecol Scand 2019 Apr;98(4):479–86. https://doi.org/10.1111/aogs.13509CrossRefGoogle ScholarPubMed
Heyborne, KD, Porreco, RP, Garite, TJ, Phair, K, Abril, D, Obstetrix/Pediatrix Research Study Group. Improved perinatal survival of monoamniotic twins with intensive inpatient monitoring. Am J Obstet Gynecol 2005;192:96101.CrossRefGoogle ScholarPubMed
MONOMONO Working Group. Inpatient vs outpatient management and timing of delivery of uncomplicated monochorionic monoamniotic twin pregnancy: the MONOMONO study. Ultrasound Obstet Gynecol 2019 Feb;53(2):175–83.Google Scholar
Van Mieghem, T, Shub, A. Management of monoamniotic twins: the question is not ‘where?’, but ‘how?Ultrasound Obstet Gynecol 2019 Feb;53(2):151–2.Google Scholar
Winkler, SS, Mustian, MN, Mertz, HL. The psychosocial impact of inpatient management of monoamniotic twin gestations. J Matern Fetal Neonatal Med 2016;29:1877–80.CrossRefGoogle ScholarPubMed
Anselem, O, Mephon, A, Le Ray, C, Marcellin, L, Cabrol, D, Goffinet, F. Continued pregnancy and vaginal delivery after 32 weeks of gestation for monoamniotic twins. Eur J Obstet Gynecol Reprod Biol 2015 Nov;194:194–8.Google Scholar

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