Skip to main content Accessibility help
×
Hostname: page-component-78c5997874-94fs2 Total loading time: 0 Render date: 2024-11-14T09:56:12.920Z Has data issue: false hasContentIssue false

5 - Examples of Immunophenotypic Features in Various Categories of Acute Leukaemia

Published online by Cambridge University Press:  01 February 2018

Anna Porwit
Affiliation:
Lunds Universitet, Sweden
Marie Christine Béné
Affiliation:
Université de Nantes, France
Get access

Summary

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2018

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Swerdlow, S.H., Campo, E., Harris, N.L., et al. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Lyon: IARC; 2008.Google Scholar
Arber, D.A., Orazi, A., Hasserjian, R., et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood; 127 (2016):2391–405.CrossRefGoogle Scholar
Arnoulet, C., Béné, M.C., Durrieu, F., et al. Four- and five-color flow cytometry analysis of leukocyte differentiation pathways in normal bone marrow: a reference document based on a systematic approach by the GTLLF and GEIL. Cytometry Part B, Clinical cytometry; 78 (2010):410.CrossRefGoogle ScholarPubMed
Lacombe, F., Durrieu, F., Briais, A., et al. Flow cytometry CD45 gating for immunophenotyping of acute myeloid leukemia. Leukemia; 11 (1997):1878–86.CrossRefGoogle ScholarPubMed
Paietta, E.. Expression of cell-surface antigens in acute promyelocytic leukaemia. Best Practice & Research Clinical Haematology; 16 (2003):369–85.CrossRefGoogle ScholarPubMed
Horna, P., Zhang, L., Sotomayor, E.M., et al. Diagnostic immunophenotype of acute promyelocytic leukemia before and early during therapy with all-trans retinoic acid. American Journal of Clinical Pathology; 142 (2014):546–52.CrossRefGoogle ScholarPubMed
Testa, U. and Lo-Coco, F.. Prognostic factors in acute promyelocytic leukemia: strategies to define high-risk patients. Annals of Hematology; 95 (2016):673–80.CrossRefGoogle ScholarPubMed
Lin, P., Hao, S., Medeiros, L.J., et al. Expression of CD2 in acute promyelocytic leukemia correlates with short form of PML-RARalpha transcripts and poorer prognosis. American Journal of Clinical Pathology; 121 (2004):402–7.CrossRefGoogle ScholarPubMed
Guglielmi, C., Martelli, M.P., Diverio, D., et al. Immunophenotype of adult and childhood acute promyelocytic leukaemia: correlation with morphology, type of PML gene breakpoint and clinical outcome. A cooperative Italian study on 196 cases. British Journal of Haematology; 102 (1998):1035–41.CrossRefGoogle Scholar
Porwit-MacDonald, A., Janossy, G., Ivory, K., et al. Leukemia-associated changes identified by quantitative flow cytometry. IV. CD34 overexpression in acute myelogenous leukemia M2 with t(8;21). Blood; 87 (1996):1162–9.CrossRefGoogle ScholarPubMed
Kita, K., Nakase, K., Miwa, H., et al. Phenotypical characteristics of acute myelocytic leukemia associated with the t(8;21)(q22;q22) chromosomal abnormality: frequent expression of immature B-cell antigen CD19 together with stem cell antigen CD34. Blood; 80 (1992):470–7.CrossRefGoogle Scholar
Iriyama, N., Hatta, Y., Takeuchi, J., et al. CD56 expression is an independent prognostic factor for relapse in acute myeloid leukemia with t(8;21). Leukemia Research; 37 (2013):1021–6.CrossRefGoogle ScholarPubMed
Bennett, J.M., Catovsky, D., Daniel, M.T., et al. Proposals for the classification of the acute leukaemias. French-American-British (FAB) co-operative group. British Journal of Haematology; 33 (1976):451–8.CrossRefGoogle ScholarPubMed
Schnittger, S., Bacher, U., Haferlach, C., et al. Rare CBFB-MYH11 fusion transcripts in AML with inv(16)/t(16;16) are associated with therapy-related AML M4eo, atypical cytomorphology, atypical immunophenotype, atypical additional chromosomal rearrangements and low white blood cell count: a study on 162 patients. Leukemia; 21 (2007):725–31.CrossRefGoogle Scholar
Martelli, M.P., Pettirossi, V., Thiede, C., et al. CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice. Blood; 116 (2010):3907–22.CrossRefGoogle Scholar
Nomdedeu, J., Bussaglia, E., Villamor, N., et al. Immunophenotype of acute myeloid leukemia with NPM mutations: prognostic impact of the leukemic compartment size. Leukemia Research; 35 (2011):163–8.CrossRefGoogle ScholarPubMed
Ferrari, A., Bussaglia, E., Ubeda, J., et al. Immunophenotype distinction between acute promyelocytic leukaemia and CD15- CD34- HLA-DR- acute myeloid leukaemia with nucleophosmin mutations. Hematological Oncology; 30 (2012):109–14.CrossRefGoogle ScholarPubMed
Angelini, D.F., Ottone, T., Guerrera, G., et al. A Leukemia-associated CD34/CD123/CD25/CD99+ immunophenotype identifies FLT3-mutated clones in acute myeloid leukemia. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research; 21 (2015):3977–85.CrossRefGoogle ScholarPubMed
Bene, M.C., Bernier, M., Casasnovas, R.O., et al. Acute myeloid leukaemia M0: haematological, immunophenotypic and cytogenetic characteristics and their prognostic significance: an analysis in 241 patients. British Journal of Haematology; 113 (2001):737–45.CrossRefGoogle ScholarPubMed
Maynadie, M., Gerland, L., Aho, S., et al. Clinical value of the quantitative expression of the three epitopes of CD34 in 300 cases of acute myeloid leukemia. Haematologica; 87 (2002):795803.Google ScholarPubMed
Derolf, A.R., Bjorklund, E., Mazur, J., et al. Expression patterns of CD33 and CD15 predict outcome in patients with acute myeloid leukemia. Leukemia & Lymphoma; 49 (2008):1279–91.CrossRefGoogle ScholarPubMed
Macedo, A., Orfao, A., Gonzalez, M., et al. Immunological detection of blast cell subpopulations in acute myeloblastic leukemia at diagnosis: implications for minimal residual disease studies. Leukemia; 9 (1995):993–8.Google ScholarPubMed
Matarraz, S., Almeida, J., Flores-Montero, J., et al. Introduction to the diagnosis and classification of monocytic-lineage leukemias by flow cytometry. Cytometry Part B, Clinical Cytometry; 3 (2017):218–27.Google Scholar
Gorczyca, W.. Flow cytometry immunophenotypic characteristics of monocytic population in acute monocytic leukemia (AML-M5), acute myelomonocytic leukemia (AML-M4), and chronic myelomonocytic leukemia (CMML). Methods in Cell Biology; 75 (2004):665–77.CrossRefGoogle ScholarPubMed
Deotare, U., Yee, K.W., Le, L.W., et al. Blastic plasmacytoid dendritic cell neoplasm with leukemic presentation: 10-Color flow cytometry diagnosis and HyperCVAD therapy. American Journal of Hematology; 91 (2016):283–6.CrossRefGoogle ScholarPubMed
Bene, M.C., Castoldi, G., Knapp, W., et al. Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL). Leukemia; 9 (1995):1783–6.Google Scholar
Lenormand, B., Bene, M.C., Lesesve, J.F., et al. PreB1 (CD10-) acute lymphoblastic leukemia: immunophenotypic and genomic characteristics, clinical features and outcome in 38 adults and 26 children. The Groupe dEtude Immunologique des Leucemies. Leukemia & Lymphoma; 28 (1998):329–42.CrossRefGoogle ScholarPubMed
Ludwig, W.D., Rieder, H., Bartram, C.R., et al. Immunophenotypic and genotypic features, clinical characteristics, and treatment outcome of adult pro-B acute lymphoblastic leukemia: results of the German multicenter trials GMALL 03/87 and 04/89. Blood; 92 (1998):1898–909.Google Scholar
Borkhardt, A., Wuchter, C., Viehmann, S., et al. Infant acute lymphoblastic leukemia - combined cytogenetic, immunophenotypical and molecular analysis of 77 cases. Leukemia; 16 (2002):1685–90.CrossRefGoogle ScholarPubMed
Hrusak, O. and Porwit-MacDonald, A.. Antigen expression patterns reflecting genotype of acute leukemias. Leukemia; 16 (2002):1233–58.CrossRefGoogle ScholarPubMed
Djokic, M., Bjorklund, E., Blennow, E., et al. Overexpression of CD123 correlates with the hyperdiploid genotype in acute lymphoblastic leukemia. Haematologica; 94 (2009):1016–19.CrossRefGoogle ScholarPubMed
Coustan-Smith, E., Mullighan, C.G., Onciu, M., et al. Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia. The Lancet Oncology; 10 (2009):147–56.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×