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Multivariate Biomarker Discovery from Part I - Framework for Multivariate Biomarker Discovery
Published online by Cambridge University Press: 30 May 2024
Chapter 2, while continuing with the concepts of importance to multivariate analysis of high-dimensional data, adds considerations related to the curse of dimensionality and descriptions of common misconceptions. Discussed is the fallacy of applying to high-dimensional data the same methods that were successfully used in low-dimensional settings. Explained are also misconceptions based on driving biomarker discovery studies by univariate and unsupervised approaches.
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