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Chapter 7 - Accidents and Injuries during Seizures

Published online by Cambridge University Press:  10 August 2021

By
Simona Lattanzi  and
Vincenzo Belcastro
Edited by
Marco Mula
Marco Mula
Affiliation:
St George's Hospital Medical School, University of London
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Summary

Epilepsy that develops following traumatic brain injury (TBI) significantly increases the risk for disability in patients with epilepsy. The house, street and workplace are the leading sites where accidents and injuries occur in patients with epilepsy. Some of the accidents and injuries may be the consequence of seizures themselves, as for example shoulder dislocation during a tonic-clonic seizure or tongue biting . Seizure-related injuries have been classified into burns, head trauma, dental traumas, fractures, major body injuries, penetrating traumas, road injuries, and drowning. Noteworthy, a patient could have one or more injuries at different body locations during a seizure or multiple injuries with different seizures.

Comorbid conditions and concurrent handicaps, neurological and cognitive deficits, behavioral and psychiatric disorders as well as side effects of antiepileptic medications, like drowsiness, ataxia, blurred vision, and diplopia, may be present in patients with epilepsy and act as independent putative causes of accidents and injuries.

Accidents and injuries that occur during seizures may require hospitalization, cause disability, influence the ability to drive and restrict driving license, increase lost work productivity and indirect costs, decrease self-esteem, contribute to social stigmatization and, hence, affect the overall quality of life in patients with epilepsy.

Keywords

post traumatic epilepsymotor vehicle accidentssymptomatic seizureshead traumaepileptogenesis
Type
Chapter
Information
Post-traumatic Epilepsy , pp. 97 - 103
Publisher: Cambridge University Press
Print publication year: 2021

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References

Beghi, E. Accidents and injuries in patients with epilepsy. Expert Rev Neurother 2009;9:291–8.Google Scholar
Tomson, T, Beghi, E, Sundqvist, A, Johannessen, SI. Medical risks in epilepsy: a review with focus on physical injuries, mortality, traffic accidents and their prevention. Epilepsy Res 2004;60:1–16.Google Scholar
Kwon, CS, Liu, M, Quan, H, et al. The incidence of injuries in persons with and without epilepsy–a population-based study. Epilepsia 2010;51:2247–53.Google Scholar
Neufeld, MY, Vishne, T, Chistik, V, Korczyn, AD. Life-long history of injuries related to seizures. Epilepsy Res 1999;34:123–7.Google Scholar
Buck, D, Baker, GA, Jacoby, A, Smith, DF, Chadwick, DW. Patients’ experiences of injury as a result of epilepsy. Epilepsia 1997;38:439–44.Google Scholar
Kirby, S, Sadler, RM. Injury and death as a result of seizures. Epilepsia 1995;36:25–8.CrossRefGoogle ScholarPubMed
van den Broek, M, Beghi, E, RESt-1 Group. Accidents in patients with epilepsy: types, circumstances, and complications: a European cohort study. Epilepsia 2004;45:667–72.Google Scholar
Gosens, T, Poels, PJE, Rondhuis, JJ. Posterior dislocation fractures of the shoulder in seizure disorders—two case reports and a review of literature. Seizure 2000;9:446–8.Google Scholar
Camfield, C, Camfield, P. Injuries from seizures are a serious, persistent problem in childhood onset epilepsy: a population-based study. Seizure 2015;27:80–3.CrossRefGoogle ScholarPubMed
Krumholz, A, Wiebe, S, Gronseth, GS, et al. Evidence-based guideline: Management of an unprovoked first seizure in adults: Report of the Guideline Development Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology 2015;84:1705–13.Google Scholar
Mahler, B, Carlsson, S, Andersson, T, Tomson, T. Risk for injuries and accidents in epilepsy: A prospective population-based cohort study. Neurology. 2018;90:e779–89.CrossRefGoogle ScholarPubMed
Asadi-Pooya, AA, Nikseresht, A, Yaghoubi, E, Nei, M. Physical injuries in patients with epilepsy and their associated risk factors. Seizure 2012;21:165–8.Google Scholar
Xu, Y, Shanthosh, J, Zhou, Z, et al. Prevalence of driving and traffic accidents among people with seizures: A systematic review. Neuroepidemiology 2019;53:1–12.Google Scholar
Kotsopoulos, IA, van Merode, T, Kessels, FG, de Krom, MC, Knottnerus, JA. Systematic review and meta-analysis of incidence studies of epilepsy and unprovoked seizures. Epilepsia 2002;43:1402–9.CrossRefGoogle ScholarPubMed
World Health Organization. Global status report on road safety 2013: supporting a decade of action. Available from: www.who.int/violence_injury_prevention/road_safety_status/2013/report/en/. Accessed December 2019.Google Scholar
Perucca, P, Hesdorffer, DC, Gilliam, FG. Response to first antiepileptic drug trial predicts health outcome in epilepsy. Epilepsia 2011; 52: 2209–15.Google Scholar
Lindsten, H, Stenlund, H, Forsgren, L. Leisure time and social activity after a newly diagnosed unprovoked epileptic seizure in adult age. A population-based case referent study. Acta Neurol Scand 2003;107:125–33.Google Scholar
Chen, J, Yan, B, Lu, H, et al. Driving among patients with epilepsy in West China. Epilepsy Behav 2014;33:1–6.Google Scholar
Sundelin, HEK, Chang, Z, Larsson, H, et al. Epilepsy, antiepileptic drugs, and serious transport accidents: a nationwide cohort study. Neurology 2018;90:e1111–8.Google Scholar
Hormia, A. Does epilepsy mean higher susceptibility to traffic accidents. Acta Psychiatr Scand Suppl 1961;36:210–2.Google Scholar
Keys, JG, Martin, CJ Jr, Barrow, RL, Fabing, HD. The epileptic automobile driver in Ohio. Ohio State Med J 1961;57:1127–31.Google ScholarPubMed
Waller, JA. Chronic medical conditions and traffic safety: review of the California experience. N Engl J Med 1965;273:413–20.CrossRefGoogle ScholarPubMed
Hansotia, P, Broste, SK. The effect of epilepsy or diabetes mellitus on the risk of automobile accidents. N Engl J Med 1991;324:22–6.CrossRefGoogle ScholarPubMed
Taylor, J, Chadwick, D, Johnson, T. Risk of accidents in drivers with epilepsy. J Neurol Neurosurg Psychiatry 1996;60:621–7.Google Scholar
Andermann, F, Rémillard, GM, Zifkin, BG, Trottier, AG, Drouin, P. Epilepsy and driving. Can J Neurol Sci 1988;15:371–7.Google Scholar
Neal, A, Carne, R, Odell, M, Ballek, D, D’Souza, WJ, Cook, MJ. Characteristics of motor vehicle crashes associated with seizure: car crash semiology. Neurology 2018;91: e1102–11.Google Scholar
Classen, S, Crizzle, AM, Winter, SM, Silver, W, Eisenschenk, S. Evidence-based review on epilepsy and driving. Epilepsy Behav 2012; 23: 103–12.Google Scholar
Krauss, GL, Krumholz, A, Carter, RC, Li, G, Kaplan, P. Risk factors for seizure-related motor vehicle crashes in patients with epilepsy. Neurology 1999;52:1324–9.Google Scholar
Sheth, SG, Krauss, G, Krumholz, A, Li, G. Mortality in epilepsy: driving fatalities vs other causes of death in patients with epilepsy. Neurology 2004;63:1002–7.Google Scholar
Berg, AT, Vickrey, BG, Sperling, MR, et al. Driving in adults with refractory localization-related epilepsy. Multi-Center Study of Epilepsy Surgery. Neurology 2000;54:625–30.Google Scholar
Sillanpää, M, Shinnar, S. Obtaining a driver’s license and seizure relapse in patients with childhood-onset epilepsy. Neurology 2005;64:680–6.Google Scholar
Faught, E, Duh, MS, Weiner, JR, Guerin, A, Cunnington, MC. Nonadherence to antiepileptic drugs and increased mortality: findings from the RANSOM Study. Neurology 2008;71:1572–78.Google Scholar
Fisher, RS, Drazkowski, JF. A comment on driving and neurologic impairment. Mayo Clin Proc 2017; 92: 1326–7.Google Scholar
Gastaut, H, Zifkin, BG. The risk of automobile accidents with seizures occurring while driving: relation to seizure type. Neurology 1987; 37: 1613–6.Google Scholar
Bonnett, LJ, Tudur-Smith, C, Williamson, PR, Marson, AG. Risk of recurrence after a first seizure and implications for driving: further analysis of the multicentre study of early epilepsy and single seizures. BMJ 2010;341:c6477.Google Scholar
Fisher, RS, Parsonage, M, Beaussart, M et al. Epilepsy and driving: an international perspective. Epilepsia 1994;35:675–84.Google Scholar
Bonnett, LJ, Shukralla, A, Tudur-Smith, C, Williamson, PR, Marson, AG. Seizure recurrence after antiepileptic drug withdrawal and the implications for driving: further results from the MRC Antiepileptic Drug Withdrawal Study and a systematic review. J Neurol Neurosurg Psychr 2011;82:1328–33.Google Scholar
Lossius, MI, Hessen, E, Mowinckel, P, et al.Consequences of antiepileptic drug withdrawal: a randomized, double-blind study (Akershus Study). Epilepsia 2008;49: 455–63.Google Scholar
Specchio, LM, Beghi, E. Should antiepileptic drugs be withdrawn in seizure-free patients? CNS Drugs 2004;18:201–12.Google Scholar
Gislason, T, Tomasson, K, Reynisdottir, H, Bjornsson, JK, Kristbjarnarson, H. Medical risk factors amongst drivers in single-car accidents. J Intern Med 1997;241:213–9.Google Scholar
Joshi, CN, Vossler, DG, Spanaki, M, Draszowki, JF, Towne, AR; Members of the Treatments Committee of the American Epilepsy Society. “Chance takers are accident makers”: Are patients with epilepsy really taking a chance when they drive? Epilepsy Curr 2019;19:221–6.Google Scholar
Mintzer, S. Driven to tears: epilepsy specialists and the automobile. Epilepsy Curr 2015;15:279–82.Google Scholar
Hansotia, P. Automobile driving and epilepsy: a medical perspective. Wis Med J 1991;90:112–5.Google Scholar
Thorbecke, R. Epilepsy and driving license in the Federal Republic of Germany and other European countries. Jpn J Psychiatry Neurol 1991;45:313–7.Google Scholar
Elliott, JO, Long, L. Perceived risk, resources, and perceptions concerning driving and epilepsy: a patient perspective. Epilepsy Behav 2008;13:381–6.Google Scholar
Zis, P, Siatouni, A, Kimiskidis, VK, et al. Disobedience and driving in patients with epilepsy in Greece. Epilepsy Behav 2014;41:179–82.Google Scholar
Hasegawa, S, Kumagai, K, Kaji, S. Epilepsy and driving: a survey of automobile accidents attributed to seizure. Jpn J Psychiatry Neurol 1991;45:327–31.Google Scholar
Takeda, A, Kawai, I, Fukushima, Y, Yagi, K. Driving and epilepsy: a prospective questionnaire survey in Japan. Committee on Driver’s Licenses, the Japan Epilepsy Society, Shizuoka. Jpn J Psychiatry Neurol 1991;45:319–22.Google Scholar
Friedman, DE, Tobias, RS, Akman, CI, Smith, EO, Levin, HS. Recurrent seizure-related injuries in people with epilepsy at a tertiary epilepsy center: a 2-year longitudinal study. EpilepsyBehav 2010;19:400–4.Google Scholar
Prasad, V, Kendrick, D, Sayal, K, Thomas, SL, West, J. Injury among children and young adults with epilepsy. Pediatrics 2014;133: 827–35.Google Scholar
Buck, D, Baker, GA, Jacoby, A, Smith, DF, Chadwick, DW. Patients’ experiences of injury as a result of epilepsy. Epilepsia 1997;38:439–44.Google Scholar
Lagunju, IA, Oyinlade, AO, Babatunde, OD. Seizure-related injuries in children and adolescents with epilepsy. EpilepsyBehav 2016;54:131–4.Google Scholar
Neufeld, MY, Vishne, T, Chistik, V, Korczyn, AD. Life-long history of injuries related to seizures. Epilepsy Res 1999;34:123–7.CrossRefGoogle ScholarPubMed
Cengiz, O, Atalar, AÇ, Tekin, B, Bebek, N, Baykan, B, Gürses, C. Impact of seizure-related injuries on quality of life. Neurol Sci 2019;40:577–83.Google Scholar
Persson, HB, Alberts, KA, Farahmand, BY, Tomson, T. Risk of extremity fractures in adult outpatients with epilepsy. Epilepsia 2002;43:768–72.Google Scholar
van den Broek, M, Beghi, E. Accidents in patients with epilepsy: types, circumstances, and complications: a European cohort study. Epilepsia 2004;45:667–72.Google ScholarPubMed

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