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58 - BONE DISORDERS AND CEREBROVASCULAR DISEASES

from PART V: - SYSTEMIC DISORDERS THAT ALSO INVOLVE THE CEREBROVASCULAR SYSTEM

Published online by Cambridge University Press:  06 January 2010

By
Natan M. Bornstein  and
Alexander Y. Gur
Edited by
Louis R. Caplan  and
Julien Bogousslavsky
Louis R. Caplan
Affiliation:
Beth Israel Deaconess Medical Center, Boston
Julien Bogousslavsky
Affiliation:
Valmont Clinique, Glion, Switzerland
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Summary

This chapter reviews rare stroke occurrences associated with specific bone disorders. The disorders have been divided into subgroups based on body bone pathology, specific skull diseases, and periodontal diseases. The phenomenon of fibrocartilaginous embolism (FE) is well documented in the veterinary literature. Multifocal ischemic encephalomyelopathy associated with fibrocartilaginous emboli was first described in a lamb by Jeffrey and Weels. Osteopetrosis (OP) is a rare, hereditary metabolic disorder of unknown etiology, characterized by an abnormal accumulation of bone mass, probably caused by diminished bone resorption. Cerebrovascular disorders of these patients have a mainly mechanical origin. Craniosynostosis may be associated with decreased cerebral blood flow as a result of the constriction of the brain because of the prematurely fused sutures. There is a relationship between premature arteriopathy with stroke and Camurati-Engelmann disease (CED). The association between periodontal disease and stroke has several possible pathophysiologic links.

Keywords

cell centrifugationfibrinogenhematocrit levelshemorheologic factorsplasma separationplasma hyperviscosity syndromesischemic strokehyperviscosity
Type
Chapter
Information
Uncommon Causes of Stroke , pp. 423 - 428
Publisher: Cambridge University Press
Print publication year: 2008

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