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Sleep regulation: physiological models and hypotheses

Published online by Cambridge University Press:  18 September 2015

A.A. Borbély
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Extract

The elucidation of sleep regulation is not an easy task. On one side, there is a multitude of solid yet disparate data, on the other side, the topic is tempting for engaging in wild speculation, particularly with respect to the functions of sleep. Models may exert a moderating influence by mediating between the two extremes. However, also they navigate between the risk of banality in reformulating the obvious, and the peril of fancy in losing touch with empirical reality.

Keywords

Two-process modelprocess S. process Cdepressionfrequency analysissleep EEGTwee processen modelprocess Sprocess Cdepressiefrequentie-analyseslaap-EEG
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 7 , Issue 2 , June 1995 , pp. 19 - 20
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1995

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References

Literature

1.Borbély, AA. A two process model of sleep regulation. Hum Neurobiol 1982; 1: 195–204.Google ScholarPubMed
2.Daan, S, Beersma, DGM. Circadian gating of human sleep-wake cycles. In Moore-Ede, MC, Czeisler, CA, eds. Mathematical models of the circadian sleep-wake cycle. New York: Raven Press 1984: 129–58.Google Scholar
3.Daan, S, Beersma, DGM, Borbély, AA. Timing of human sleep: Recovery process gated by a circadian pacemaker. Am J Physiol 1984; 246: R161–78.Google ScholarPubMed
4.Borbély, AA, Achermann, P. Concepts and models of sleep regulation: an overview. J Sleep Res 1992; 1: 63–79.CrossRefGoogle ScholarPubMed
5.Achermann, P, Dijk, DJ, Brunner, DP, Borbély, AA. A model of human sleep homeostasis based on EEG slow-wave activity: quantitative comparison of data and simulations. Brain Res Bull 1993; 31: 97–113.CrossRefGoogle Scholar
6.Tobler, I, Franken, P, Trachsel, L, Borbély, AA. Models of sleep regulation in mammals. J Sleep Res 1992; 1: 125–7.CrossRefGoogle ScholarPubMed
7.Borbély, AA, Neuhaus, H-U. Sleep-deprivation: Effects on sleep and EEG in the rat. J Comp Physiol 1979; 133: 71–87.CrossRefGoogle Scholar
8.Borbély, AA, Baumann, F, Brandeis, D, Strauch, I, Lehmann, D. Sleep-deprivation: Effect on sleep stages and EEG power density in man. Electroencephalogr clin Neurophysiol 1981; 51: 483–93.CrossRefGoogle ScholarPubMed
9.Lancel, M, van Riezen, H, Glatt, A. The time course of sigma activity during NREMS in cortical and thalamic EEG of the cat during baseline and after 12 hours of wakefulness. Brain Res 1992; 596: 285–95.CrossRefGoogle ScholarPubMed
10.Steriade, M, McCormick, DA, Sejnowski, TJ. Thalamocortical oscillations in the sleeping and aroused brain. Science 1993; 262: 679–85.CrossRefGoogle ScholarPubMed
11.Steriade, M, Contreras, D, Amzica, F. Synchronized sleep oscillations and their paroxysmal developments. Trends Neuro sci 1994; 17: 199–208.CrossRefGoogle ScholarPubMed
12.Aeschbach, D, Borbély, AA. All-night dynamics of the human sleep EEG. J Sleep Res 1993; 2: 70–81.CrossRefGoogle ScholarPubMed
13.Dijk, DJ, Hayes, B, Czeisler, CA. Dynamics of electroencephalo-graphic sleep spindles and slow wave activity in men: effect of sleep deprivation. Brain Res 1993; 626: 190–9.CrossRefGoogle Scholar
14.Franken, P, Dijk, DJ, Tobler, I, Borbély, AA. High frequency components of the rat electroencephalogram are modulated by the vigilance states. Neurosci Lett 1994; 167: 89–92.CrossRefGoogle ScholarPubMed
15.Dijk, DJ, Beersma, DGM, Daan, S. Bright morning light advances the human circadian system without affecting NREM sleep homeostasis. Am J Physiol 1989; 256: R106–11.Google Scholar
16.Franken, P, Tobler, I, Borbély, AA. Sleep and waking have a major effect on the 24-h rhythm in the rat. J biol Rhythms 1992; 7: 341–52.CrossRefGoogle Scholar
17.Dijk, DJ, Czeisler, CA. Paradoxical timing of the circadian rhythm of sleep propensity serves the consolidation of sleep and wakefulness in humans. Neurosci Lett 1994; 166: 63–8.CrossRefGoogle ScholarPubMed
18.Dijk, DJ, Czeisler, CA. Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves and sleep spindle activity in humans. J Neurosci 1995; 15: 3526–38.CrossRefGoogle ScholarPubMed
19.Folkard, S, Åkerstedt, T. A three-process model of the regulation of alertness-sleepiness. In: Broughton, RJ, Ogilvie, RD, eds. Sleep, Arousal, and Performance. Boston, Basel, Berlin: Birkhäuser, 1992: 11–26.Google Scholar
20.Achermann, P, Borbély, AA. Simulation of daytime vigilance by additive interaction of a homeostatic and a circadian process. Biol Cybernetics 1994; 71: 115–21.CrossRefGoogle Scholar
21.Borbély, AA, Wirz-Justice, A. Sleep, sleep deprivation and depression. A hypothesis derived from a model of sleep regulation. Hum Neurobiol 1982; 1: 205–10.Google Scholar
22.Wehr, TA, Wirz-Justice, A, Goodwin, FK. Phase advance of the circadian sleep-wake cycle as an antidepressant. Science 1979; 206: 710–3.CrossRefGoogle ScholarPubMed
23.Wehr, TA, Wirz-Justice, A. Internal coincidence model for sleep deprivation and depression. In Koella, WP, ed. Sleep 1980. Basel: Karger, 1981: 26–33.Google Scholar
24.Gillin, JC, Borbély, AA. Sleep: a neurobiological window on affective disorders. Trends Neurosci 1985; 8: 537–42.CrossRefGoogle Scholar
25.Benca, RM. Mood Disorders. In Kryger, MH, Roth, T, Dement, WC, eds. Principles and Practice of Sleep Medicine. Second Edition. Philadelphia: W.B. Saunders Company, 1994: 899.Google Scholar
26.Van den Hoofdakker, RH. Chronobiological theories of nonseasonal affective disorders and their implications for treatment. J biol Rhythms 1994; 9: 157–83.CrossRefGoogle ScholarPubMed
27.Beersma, DGM, Van den Hoofdakker, RH. Can Non-REM sleep be depressogenic? J affect Disord 1992; 24: 101–8.CrossRefGoogle Scholar